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Chromosulfuric acid is a corrosive oxidation reagent composed of a mixture of concentrated sulfuric acid and dichromate. The acid can be used to clean laboratory glassware of otherwise insoluble organic residues and has a variety of industrial applications.
A bile acid; formed by 7α-hydroxylation of 27-hydroxycholesterol; precursor in the biosynthesis of chenodeoxycholic acid; levels are increased in patients with neonatal liver disease harboring mutations in CYP7A1, as well as in patients with intrahepatic and extrahepatic cholestasis
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One of several monounsaturated 20-carbon fatty acids; combined C20:1 isomers constitute approximately 70% of the total fatty acid pool in jojoba seed oil
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A cyclohexenecarboxylic acid; an intermediate in the biosynthesis of aromatic amino acids in plants and microorganisms; a precursor in the synthesis of oseltamivir; decreases lipid droplet accumulation in HepG2 cells and 3T3-L1 adipocytes at 80 µM; increases the levels of phosphorylated AMPK and decreases the levels of MID1IP1 in HepG2 and 3T3-L1 adipocytes at 40 µM; decreases inflammation and demyelination in a mouse model of EAE at 50-200 mg/kg and reduces symptom progression at 100 mg/kg
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A metabolite of L-lysine; inhibits GABA binding in bovine brain homogenate in the presence, but not absence, of hexobarbital or pentobarbital (IC50s = 0.2 and 2 nM, respectively); serum levels are elevated in patients with Zellweger syndrome
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A long-chain ω-3 PUFA; comprises approximately 40% of total brain PUFAs and is abundant in grey matter and retinal membranes; typically represents 0.52-7.5% of human total plasma fatty acids; has roles in several physiological and pathological processes
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A monounsaturated fatty acid; potentiates ACh receptor channel currents without depression and enhances PCKε phosphorylation of a substrate peptide in Xenopus oocytes; constitutes 6% of the fatty acid pool in seed oil isolated from B. collina
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13(Z)-Docosenoic acid is a 22-carbon monounsaturated fatty acid. It is found predominantly in canola oil.{8144} 13(Z)-Docosenoic acid is metabolized to oleic acid in vivo. Diets rich in 13(Z)-docosenoic acid were shown to cause heart lipidosis in experimental animals.{7786,8145} The C-1 amide of docosenoic acid has been identified as one of the anandamide-related neurotransmitters associated with sleep.{1317}
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A quinolone antibiotic; active against Gram-positive and Gram-negative bacteria including S. aureus and E. coli (MICs = 10 and 1 UG/ml, respectively); inhibits growth of nalidixic acid-sensitive strains of E. coli in an in vitro model of bacterial cystitis at 10 and 50 mg/L; active against chloroquine-sensitive and -resistant strains of P. falciparum in vitro (IC50s = 41.4 and 14.4 UG/ml, respectively) and against hepatic stages of P. yoelii yoelii (IC50 = 21.6 UG/ml)
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An L-ascorbic acid and stearic acid derivative with antioxidant and anticancer activities; scavenges DPPH in a cell-free assay (IC50 = 3.31 UG/ml); LNPs encapsulating L-ascorbic acid 6-stearate induce apoptosis in HL-60 cells at 190 µM
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A fungal metabolite with fungicidal activity; active against the plant pathogenic fungus F. graminearum; has been used as a substrate in the determination of PON1 activity; has been used in the chemiluminescent detection of HRP release from liposomes; an intermediate in the synthesis of the near-infrared lipid droplet probe LD-2
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