Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Newcomer Supply Decalcifying Solution, Formic Acid 5%, Aqueous, 1 gallon
Newcomer Supply Decalcifying Solution, Formic Acid, 5% Aqueous, provides a moderate rate of decalcification while maintaining excellent cellular morphology. This solution is a general purpose decalcifier and is suitable for all bone specimen types from sternal or iliac crest bone marrow biopsies (light bone) to femoral head and long bone sections (compact bone). Shelf Life is 1 year from date of manufacture. Store at 15-30°C.
Medchemexpress LLC PKCiota-IN-2 formic | 99.04% | 402.36 | 50 MG
PKCiota-IN-2 formic is a potent inhibitor of PKCiota (PKC-ι), with an IC50 of 2.8 nM. It also demonstrates inhibitory activity against PKC-α and PKC-ε, exhibiting IC50s of 71 nM and 350 nM, respectively. This product is intended for research use only and is not for sale to patients.
- Potent inhibition of PKCiota.
- Exhibits inhibitory effects on PKC-alpha and PKC-epsilon.
- Available in various quantities, including solid and solution forms.
Medchemexpress LLC PKCiota-IN-2 formic | 99.0% | 402.36 | 100 MG
PKCiota-IN-2 formic is a potent inhibitor of PKCiota (PKC-ι) with an IC50 of 2.8 nM. It also demonstrates inhibitory activity against PKC-α and PKC-ε.
- Potent PKCiota (PKC-ι) inhibitor.
- Inhibits PKC-α and PKC-ε.
- Available in solid and solution forms.
- Purity: 99.04%.
- For research use only.
Medchemexpress LLC PKCiota-IN-2 formic | 99.0% | 402.36 | 1 ML
PKCiota-IN-2 formic is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. It also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively.
- Potent PKCiota inhibitor with an IC50 of 2.8 nM.
- Also inhibits PKC-α with an IC50 of 71 nM.
- Inhibits PKC-ε with an IC50 of 350 nM.
Medchemexpress LLC LCC-12 (formic) | 3029253-76-4 | 99.9% | 460.57 | 5 MG
LCC-12 formic is a dimer of metformin that targets mitochondrial copper(II), leading to a decrease in the NAD(H) pool and modulation of inflammatory responses. It reduces inflammation in mouse models of bacterial and viral infections and serves as a tool for investigating metabolic diseases through its effects on cell plasticity and epigenetic programming.
- Targets mitochondrial copper(II).
- Decreases the NAD(H) pool.
- Modulates inflammatory responses.
- Reduces inflammation in mouse models of bacterial and viral infections.
- Serves as a tool for investigating metabolic diseases.
- Affects cell plasticity.
- Affects epigenetic programming.
eMolecules Oakwood Chemicals Formic Acid ACS Grade 20kg 480143866 093996 0 000 64-18-6 MFCD00003297 46 025 CH2O2
Oakwood Chemicals Formic Acid ACS Grade 20kg 480143866 093996 0 000 64-18-6 MFCD00003297 46 025 CH2O2
Medchemexpress LLC PKCiota-IN-2 formic | 2230055-52-2 | 99.0% | 402.36 | 25 MG
PKCiota-IN-2 formic is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. It also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively. This product is for research use only.
- Appearance: Solid
- Color: Light yellow to yellow
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture and light. In solvent, store at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture and light).
- Solubility (in vitro): DMSO: 100 mg/mL (248.53 mM; requires ultrasonic).