Malic Acid
Cayman Chemical DL-MalIc AcId 250g
The racemate of L-malic acid; reduces IFN-γ and TNF-α-induced CCL2 and ICAM expression in HaCaT human keratinocytes at 1 mM; inhibits epidermis and dermis thickening, as well as mast cell and eosinophil dermal infiltration in a mouse model of DNBC-induced atopic dermatitis at 10 mM
Chem-Impex International, Inc. L-Malic acid | 97-67-6 | MFCD00064213 | 1KG
L-Malic acid, 97-67-6, MFCD00064213, 1KG
Accela Chembio Inc D-(+)-malic Acid | 25g | 636-61-3 | MFCD00004245 | 97+% | D: 1.6 | Shelf Life: 1260 Days | Light Sensitive
D-(+)-malic Acid | 25g | 636-61-3 | MFCD00004245 | 97+% | D: 1.6 | Shelf Life: 1260 Days | Light Sensitive
Chem-Impex International, Inc. D-(+)-Malic acid | 636-61-3 | MFCD00004245 | 5G
D-(+)-Malic acid, 636-61-3, MFCD00004245, 5G
Medchemexpress LLC Malic dehydrogenase, microorganism | 9001-64-3 | ≥10 U/mg solid | about 35,000 | 1 KU
Malate dehydrogenase (EC 1.1.1.37) (MDH) is an enzyme that catalyzes the mutual conversion of oxaloacetate and malate. It is associated with the oxidation/reduction of dinucleotide coenzymes.
- Optimum pH 7.5-8.0
- Optimum temperature 60°C
- pH stability 3.0-9.0 (37°C, 30 minutes)
- Thermal stability below 65°C (pH 7.5, 30 minutes)
Medchemexpress LLC (S)-malic acid-13C4 | 150992-96-4 | MFCD19704799 | 98.0% | 138.06 | 13C4H6O5 | 1mg
(S)-Malic acid-13C4 is the 13C labeled S-Malic acid (HY-Y1069)[1]
Alkali Scientific L Malic Acid, 3 Kg
L Malic Acid is an organic dicarboxylic acid naturally found in many fruits and widely used in biochemical and analytical laboratory research. It plays an important role in cellular metabolism as an intermediate of the tricarboxylic acid (TCA) cycle, a central pathway in energy production within living cells. In laboratory environments, L Malic Acid is used in biochemical assays, metabolic pathway studies, and analytical applications requiring organic acid standards. Researchers utilize it to investigate metabolic reactions, enzyme activity, and cellular respiration processes. Its stability and well characterized chemical properties make it suitable for biochemical research, analytical testing, and laboratory experiments involving organic acid metabolism.
TARGETMOL CHEMICALS INC IBIGLUSTAT L-MALIC ACID 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective brain-penetrant and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic acid) can be used in studies about PD Parkinson’s disease SRT in Fabry’s and Gaucher’s. purity: 99%
Medchemexpress LLC L-malic acid-13C4 | 150992-96-4 | MFCD19704799 | 98.0% | 138.06 g/mol | 13C4H6O5 | 5mg
(S)-Malic acid-13C4 is the 13C labeled S-Malic acid (HY-Y1069)[1]
Medchemexpress LLC Ibiglustat (L-Malic acid) | 1629063-78-0 | 523.57 | 10 MM 1 ML
Ibiglustat (Venglustat) L-Malic acid is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. It is utilized in the research of various conditions such as Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease. Studies suggest it can prevent additional GL-3 accumulation and ameliorate sphingolipid levels in conditions like Fabry disease.
- Orally active, brain-penetrant GCS inhibitor
- Used in research for Gaucher disease type 3
- Used in research for Parkinson's disease with GBA mutations
- Used in research for Fabry disease
- Used in research for GM2 gangliosidosis
- Used in research for autosomal dominant polycystic kidney disease
- Prevents GL-3 accumulation
- Ameliorates sphingolipid levels
Medchemexpress LLC D-(+)-Malic acid | 636-61-3 | 99.8% | 134.09 | 1 ML
D-(+)-Malic acid (D-Malic acid) is an active enantiomer of Malic acid that functions as a competitive inhibitor of L(-)malic acid transport. It is an endogenous metabolite.
- Active enantiomer of malic acid
- Competitive inhibitor of L(-)malic acid transport
- Can be produced from maleic acid by certain bacteria
Medchemexpress LLC Malic enzyme inhibitor ME1 | 522649-59-8 | 99.7% | 351.40 | 10 MG
Malic enzyme inhibitor ME1 is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM. It significantly reduces total cell numbers and cell viability/metabolic activity in MTS cells and dose-dependently reduces the number of colonies formed by HCT116 and HT29 cells. This product is for research use only.
- Potent inhibitor of malic enzyme (ME1) with an IC50 of 0.15 μM
- Reduces total cell numbers and cell viability in MTS cells
- Dose-dependently reduces colony formation in HCT116 and HT29 cells
- Appears as a white to off-white solid
Cayman Chemical DL-MalIc AcId 100g
The racemate of L-malic acid; reduces IFN-γ and TNF-α-induced CCL2 and ICAM expression in HaCaT human keratinocytes at 1 mM; inhibits epidermis and dermis thickening, as well as mast cell and eosinophil dermal infiltration in a mouse model of DNBC-induced atopic dermatitis at 10 mM