Acyl bromides
TARGETMOL CHEMICALS INC Clidinium bromide 500MG
Also available in 1 mL, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can inhibit muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also to help relieve cramps or stomach spasms or abdominal due to colicky abdominal diverticulitis, pain, and irritable bowel syndrome. Purity 99.36%
Apexbio Technology LLC Tiotropium Bromide hydrate 139404-48-1 50mg
Tiotropium Bromide hydrate is a small-molecule antagonist targeting muscarinic acetylcholine receptors (mAChRs) It is designed to competitively inhibit mAChRs thereby modulating airway smooth muscle contraction and mediating bronchodilation Tiotropium Bromide hydrate exerts its biological activity primarily through competitive antagonism at mAChRs resulting in relaxation of airway smooth muscle Based on these pharmacological properties Tiotropium Bromide hydrate holds research potential in respiratory pharmacology particularly for investigating mechanistic pathways in chronic obstructive pulmonary disease (COPD) receptor-ligand interactions and pulmonary pharmacodynamics associated with airway obstruction
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 5mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
eMolecules Chem-Impex Copper(II) bromide 5kg 342449732 24557 0 000 7789-45-9 MFCD00010970 223 354 Br2Cu
Chem-Impex Copper(II) bromide 5kg 342449732 24557 0 000 7789-45-9 MFCD00010970 223 354 Br2Cu
Medchemexpress LLC IEM 1925 dihydrobromide | 258282-23-4 | 98.0% | 422.24 | C17H30Br2N2 | 5 MG
IEM-1925 dihydrobromide is the dihydrobromide salt of IEM-1925, a use- and voltage-dependent open-channel antagonist of AMPA (glutamate) receptors. It is supplied as a high-purity solid for research use in pharmacology, electrophysiology, and seizure-model studies.
- Chemical formula: C17H30Br2N2.
- Cas number: 258282-23-4.
- Molecular weight: 422.24.
- Purity: 98.0%.
- Appearance: solid.
- Typical applications: AMPA receptor pharmacology and seizure-model research.
- Available pack sizes: 5 mg, 10 mg.