Alkyl fluorides
Proteochem Inc HFBA Ampules (Proteomics Grade), 375-22-4, MFCD00004171, 10x1 mL
MF: C4 H F7 O2, MW: 214.04, Alternative Names: HFBA; Heptafluorobutanoic acid; Perfluorobutanoic acid; Perfluorobutyric acid; 2,2,3,3,4,4,4-Heptafluorobutanoic acid. Heptafluorobutyric Acid (HFBA) is an ion pairing agent for reverse-phase HPLC separation of peptides or proteins.
Sigma Aldrich Fine Chemicals Biosciences Heptafluorobutyric acid 99
HEPTAFLUOROBUTYRIC9 Heptafluorobutyric acid 99
AdipoGen PFOA ammonium salt
Chemical. CAS 3825-26-1. Formula C8HF15O2 . NH3. Molecular Weight 431.1. Perfluorooctanoate PFOA is the dissociated carboxylate anion of perfluorooctanoic acid and its salts. PFOA is a stable, soluble surfactant primarily used in the form of the ammonium salt APFO as a processing aid in the production of various fluoropolymers. It is a very active fluorosurfactant with high stability.
Medchemexpress LLC 2-Pyridinecarbonitrile, 5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]- | 675103-36-3 | 99.6% | 400.35 | 25 MG
2-Pyridinecarbonitrile, 5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]- | 675103-36-3 | 99.6% | 400.35 | 25 MG
TARGETMOL CHEMICALS INC BAY-678 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BAY-678 is a human neutrophil elastase (HNE; IC50 20 nM) inhibitor with oral bioactivity potency and selectivity.BAY-678 is a chemical probe recommended by the Structural Genomics Consortium (SGC). purity: 98%
Medchemexpress LLC BAY-678 | 675103-36-3 | 99.6% | 400.35 | 1 ML
BAY-678 is an orally bioavailable, highly potent, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC₅₀ of 20 nM. It has been nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). It demonstrates significant efficacy in preclinical models of ALI and lung emphysema, showing anti-inflammatory and anti-remodeling actions. Additionally, it has shown beneficial pulmonary hemodynamic and vascular effects in models of PAH in rats and mice.
- Orally bioavailable and cell-permeable inhibitor of human neutrophil elastase
- Exhibits more than 2,000-fold selectivity in a panel of 21 serine proteases
- Shows significant efficacy in preclinical models of ALI and lung emphysema
- Demonstrates anti-inflammatory and anti-remodeling modes of action
- Beneficial pulmonary hemodynamic and vascular effects in models of PAH
Medchemexpress LLC Cholesterol n-Octano 1g
Cholesterol n-Octanoate is an organic compound belonging to the class of esters It is formed from the reaction between cholesterol and caprylic acid Cholesterol n-octanoate has various applications in the pharmaceutical industry notably as a bioactive compound with potential research potential to improve a range of medical conditions such as high cholesterol and inflammation-related diseases Additionally it has potential applications as a food additive to improve texture and stability
Medchemexpress LLC N-Boc-8-amino-octanoic acid | 30100-16-4 | MFCD00270350 | >=97.0% | 259.34 g/mol | C13H25NO4 | 10 G
N-Boc-8-amino-octanoic acid is a Boc-protected amino acid used as a linker building block in PROTAC and peptide synthesis. It contains a terminal carboxylic acid and a tert-butyloxycarbonyl (Boc)-protected amine, suitable for amide coupling and mild acidic deprotection.
- Molecular formula: C13H25NO4
- Molecular weight: 259.34 g/mol
- Cas number: 30100-16-4
- Purity: ≥97.0%
- Appearance: white to off-white solid
- Storage: store at room temperature; in solvent store at -80°C (2 years) or -20°C (1 year)
- Typical applications: protac linker and peptide or small-molecule synthesis
Medchemexpress LLC N-Boc-8-amino-octanoic acid | 30100-16-4 | MFCD00270350 | >97.0% | 259.34 g/mol | C13H25NO4 | 5 G
N-Boc-8-amino-octanoic acid is a Boc-protected amino acid used as a linker and building block in small-molecule synthesis, including proteolysis-targeting chimera (PROTAC) construction. It contains a Boc-protected terminal amine and a terminal carboxylic acid that can be activated for amide formation.
- Boc-protected terminal amine for temporary protection
- Terminal carboxylic acid suitable for activation and amide coupling
- High purity (>97.0%) suitable for synthetic applications
- Available in small pack sizes, including 5 G
- Stable as a solid at room temperature for extended storage
Medchemexpress LLC BAY-678 | 675103-36-3 | 99.6% | 400.35 | 100 MG
BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. It is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
- Orally bioavailable.
- Highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE).
- IC50 of 20 nM for HNE.
- Nominated as a chemical probe via the Structural Genomics Consortium (SGC).
- Ki value for MNE is 700 nM.
- 4th generation inhibitor of HNE.
- More than 2,000-fold selectivity in a panel of 21 serine proteases.
- Reveals significant efficacy in preclinical models of ALI and lung emphysema, demonstrating anti-inflammatory and anti-remodeling mode of action.
- Shown significant beneficial pulmonary hemodynamic and vascular effects in models of PAH in rats and mice.