Alkyl fluorides
Cayman Chemical 2H 2H 3H 3H-Perfluorodecanoic
A polyfluoroalkyl substance; has been found as a contaminant in freshwater reserves and marine seafood
Matrix Scientific PENTAFLUOROPROPIONIC ANHYDRIDE MF C6F10O3 MW 310.05 CAS 356-42-3 MDL MFCD00000429 QTY 5 UOM G
PENTAFLUOROPROPIONIC ANHYDRIDE MF C6F10O3 MW 310.05 CAS 356-42-3 MDL MFCD00000429 QTY 5 UOM G
Sigma Aldrich Fine Chemicals Biosciences Heptafluorobutyric anhydride >=98% | 336-59-4 | MFCD00000432 | 10AMP
Heptafluorobutyric anhydride >=98% | Purity: >=98% | Mol Wt: 410.06 | 336-59-4 | MFCD00000432 | 10AMP
Medchemexpress LLC 2-Pyridinecarbonitrile, 5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]- | 675103-36-3 | 99.6% | 400.35 | 25 MG
2-Pyridinecarbonitrile, 5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]- | 675103-36-3 | 99.6% | 400.35 | 25 MG
TARGETMOL CHEMICALS INC BAY-678 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BAY-678 is a human neutrophil elastase (HNE; IC50 20 nM) inhibitor with oral bioactivity potency and selectivity.BAY-678 is a chemical probe recommended by the Structural Genomics Consortium (SGC). purity: 98%
Medchemexpress LLC BAY-678 | 675103-36-3 | 99.6% | 400.35 | 1 ML
BAY-678 is an orally bioavailable, highly potent, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC₅₀ of 20 nM. It has been nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). It demonstrates significant efficacy in preclinical models of ALI and lung emphysema, showing anti-inflammatory and anti-remodeling actions. Additionally, it has shown beneficial pulmonary hemodynamic and vascular effects in models of PAH in rats and mice.
- Orally bioavailable and cell-permeable inhibitor of human neutrophil elastase
- Exhibits more than 2,000-fold selectivity in a panel of 21 serine proteases
- Shows significant efficacy in preclinical models of ALI and lung emphysema
- Demonstrates anti-inflammatory and anti-remodeling modes of action
- Beneficial pulmonary hemodynamic and vascular effects in models of PAH
Medchemexpress LLC Cholesterol n-Octano 1g
Cholesterol n-Octanoate is an organic compound belonging to the class of esters It is formed from the reaction between cholesterol and caprylic acid Cholesterol n-octanoate has various applications in the pharmaceutical industry notably as a bioactive compound with potential research potential to improve a range of medical conditions such as high cholesterol and inflammation-related diseases Additionally it has potential applications as a food additive to improve texture and stability
Medchemexpress LLC N-Boc-8-amino-octanoic acid | 30100-16-4 | MFCD00270350 | >=97.0% | 259.34 g/mol | C13H25NO4 | 10 G
N-Boc-8-amino-octanoic acid is a Boc-protected amino acid used as a linker building block in PROTAC and peptide synthesis. It contains a terminal carboxylic acid and a tert-butyloxycarbonyl (Boc)-protected amine, suitable for amide coupling and mild acidic deprotection.
- Molecular formula: C13H25NO4
- Molecular weight: 259.34 g/mol
- Cas number: 30100-16-4
- Purity: ≥97.0%
- Appearance: white to off-white solid
- Storage: store at room temperature; in solvent store at -80°C (2 years) or -20°C (1 year)
- Typical applications: protac linker and peptide or small-molecule synthesis
Medchemexpress LLC N-Boc-8-amino-octanoic acid | 30100-16-4 | MFCD00270350 | >97.0% | 259.34 g/mol | C13H25NO4 | 5 G
N-Boc-8-amino-octanoic acid is a Boc-protected amino acid used as a linker and building block in small-molecule synthesis, including proteolysis-targeting chimera (PROTAC) construction. It contains a Boc-protected terminal amine and a terminal carboxylic acid that can be activated for amide formation.
- Boc-protected terminal amine for temporary protection
- Terminal carboxylic acid suitable for activation and amide coupling
- High purity (>97.0%) suitable for synthetic applications
- Available in small pack sizes, including 5 G
- Stable as a solid at room temperature for extended storage
Medchemexpress LLC BAY-678 | 675103-36-3 | 99.6% | 400.35 | 100 MG
BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. It is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
- Orally bioavailable.
- Highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE).
- IC50 of 20 nM for HNE.
- Nominated as a chemical probe via the Structural Genomics Consortium (SGC).
- Ki value for MNE is 700 nM.
- 4th generation inhibitor of HNE.
- More than 2,000-fold selectivity in a panel of 21 serine proteases.
- Reveals significant efficacy in preclinical models of ALI and lung emphysema, demonstrating anti-inflammatory and anti-remodeling mode of action.
- Shown significant beneficial pulmonary hemodynamic and vascular effects in models of PAH in rats and mice.
Matrix Scientific 1H,1H,2H,2H-PERFLUOROOCTAN-1-OL MF C8H5F13O MW 364.11 CAS 647-42-7 MDL MFCD00042143 QTY 25 UOM G
1H,1H,2H,2H-PERFLUOROOCTAN-1-OL MF C8H5F13O MW 364.11 CAS 647-42-7 MDL MFCD00042143 QTY 25 UOM G
Medchemexpress LLC Perfluorohexanoic acid | 307-24-4 | 99.9% | 314.05 | 50 G
Perfluorohexanoic acid (Undecafluorocaproic acid) is a biological molecule intended for research use only. It is not for sale to patients. This substance appears solid below 12 °C and liquid above 14 °C, with a colorless to off-white appearance.
- Biological molecule
- Biochemical assay reagent control
- For research use only
- Colorless to off-white appearance
- Solid below 12 °C, liquid above 14 °C
Medchemexpress LLC X-376 (Ensartinib) | 1365267-27-1 | 98.1% | 547.41 | 100 MG
X-376 is a potent and highly specific ALK tyrosine kinase inhibitor (TKI) (IC50=0.61 nM). It is a less potent inhibitor of MET (IC50=0.69 nM) and displays potent anti-tumor activity.
- Potent and highly specific ALK tyrosine kinase inhibitor
- Less potent inhibitor of MET
- Displays potent anti-tumor activity