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Filtered Search Results
Apexbio Technology LLC AZD 5153(Synonyms: AZD5153, AZD-5153, AZD 5153 dihydrochloride, BRD4 inhibitor AZD5153, AZD5153 BRD4 inhibitor), 25mg, CAS: 1869912-39-9.
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AZD5153 (CAS 1869912-39-9) is a potent selective orally bioavailable inhibitor of the bromodomain and extraterminal (BET) family protein BRD4 Through simultaneous binding of both bromodomains in BRD4 AZD5153 effectively disrupts BRD4-mediated transcriptional regulation In cellular assays AZD5153 demonstrates high activity notably displacing BRD4 with an IC50 of approximately 1 7 nM in U2OS cells It significantly inhibits growth of AML multiple myeloma and diffuse large B-cell lymphoma cell lines reducing mTOR pathway signaling In vivo AZD5153 shows dose-dependent antitumor efficacy in xenograft models of hematologic malignancies indicating its value as a tool compound in cancer research
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eMolecules 1141-38-4 | naphthalene-2,6-dicarboxylic acid | Pharmablock | MFCD00004105 | 216.192 | C12H8O4 | 97.000 | OC(=O)c1ccc2cc(ccc2c1)C(O)=O | 500mg | 551084514
naphthalene-2,6-dicarboxylic acid | Pharmablock | 1141-38-4 | MFCD00004105 | 216.192 | C12H8O4 | 97.000 | OC(=O)c1ccc2cc(ccc2c1)C(O)=O | 500mg | 551084514
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Selleck Chemical LLC GSK 5959
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GSK5959 is a potent and selective BRPF1 bromodomain inhibitor with an IC50 of 80 nM and exhibits 100-fold selectivity for BRPF1 over a panel of 35 other bromodomains including BRPF2/3 and BET family bromodomains
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Chemscene ChemScene | 6-Hydroxy-1-naphthoic acid | 10G | CS-W016818 | 0.98 | 2437-17-4| MFCD00209983 | 188.18
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ChemScene | 6-Hydroxy-1-naphthoic acid | 10G | CS-W016818 | 0.98 | 2437-17-4| MFCD00209983 | 188.18
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Chemscene ChemScene | Methyl 3-bromo-1-naphthoate | 250MG | CS-0074270 | 0.98 | 16650-63-8| MFCD06658478 | 265.11
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ChemScene | Methyl 3-bromo-1-naphthoate | 250MG | CS-0074270 | 0.98 | 16650-63-8| MFCD06658478 | 265.11
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Selleck Chemical LLC 1-Hydroxy-2-naphthoic acid
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1-Hydroxy-2-naphthoic acid is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms
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Chemscene ChemScene | 3-Bromo-1-naphthoic acid | 250MG | CS-0139704 | 0.98 | 16726-66-2| MFCD06658377 | 251.079
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ChemScene | 3-Bromo-1-naphthoic acid | 250MG | CS-0139704 | 0.98 | 16726-66-2| MFCD06658377 | 251.079
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Cayman Chemical 4-hydroxy Chalcon 10g
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A chalcone metabolite; estrogenic and cytotoxic in MCF-7 cells at concentrations higher than 100 nM; inhibits TNF-α-induced NF-κB signaling and the trypsin-, chymotrypsin-, and caspase-like proteolytic activities of the 26S proteasome in K562 cells in a dose-dependent manner; reduces growth of K562, U937, and Jurkat cancer cell lines in a dose-dependent manner without effecting viability of PBMCs; inhibits GSH-RD (IC50 = 47.3 μM) in vitro in a reversible and non-competitive manner
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Medchemexpress LLC Ald-Ph-NHS ester | 60444-78-2 | 98.6% | 247.20 g/mol | C12H9NO5 | 100 MG
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Ald-Ph-NHS ester is a non-cleavable linker reagent used for antibody-agent conjugation (ADC) in research applications. The compound features an N-hydroxysuccinimide (NHS) ester for efficient coupling to primary amines, producing stable, non-cleavable conjugates suitable for bioconjugation workflows.
- Non-cleavable NHS ester linker for ADC conjugation.
- High purity (98.56%).
- Soluble in DMSO; may require sonication and anhydrous solvent.
- CAS number 60444-78-2; molecular weight 247.20 g/mol.
- Store solid sealed at 4°C; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
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Medchemexpress LLC Olodaterol (hydrochloride) (standard) | 869477-96-3 | 99.4% | C₂₁H₂₇ClN₂O₅ | 25 MG
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Olodaterol hydrochloride is a chemical standard identified for laboratory use and substance manufacturing. It appears as a white solid with a molecular weight of 422.90 and a high purity of 99.4%.
- Suitable for laboratory research
- Used in the manufacture of substances
- White solid appearance
- High purity (99.4%)
- Consistent with structure by 1H NMR and MS
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Aobchem AOBCHEM
5001071426 N N-DIMETHYL-1-NAPHTHALENESULF
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Aobchem AOBCHEM
5001071464 N-CYCLOHEXYL-2-NAPHTHALENESULF
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Aobchem AOBCHEM
5001071544 N-CYCLOPROPYL-2-NAPHTHALENESUL
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Aobchem AOBCHEM
5001071553 N N-DIMETHYL-2-NAPHTHALENESULF
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eMolecules 7149-49-7 | Ambeed | Naphthalene-23-dicarbaldehyde | 100mg | 586037497 | A770576 | MFCD00016618 | 184.194 | C12H8O2
Ambeed | Naphthalene-23-dicarbaldehyde | 100mg | 586037497 | A770576 | 7149-49-7 | MFCD00016618 | 184.194 | C12H8O2
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