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Filtered Search Results
Apexbio Technology LLC Adapalene 106685-40-9 100mg
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Adapalene (106685-40-9) is a small-molecule agonist targeting retinoic acid receptor subtypes RAR and RAR with lower affinity for RAR and minimal activity toward RXR It is designed to selectively modulate retinoic acid receptor-mediated gene transcription thereby regulating cellular growth differentiation and apoptosis Adapalene exerts its biological activity primarily through selective activation of RAR and RAR subtypes In experimental models adapalene exhibits agonistic activity with Ki values of 2 3 nM for RAR 9 3 nM for RAR and 22 nM for RAR Based on these pharmacological properties adapalene holds research potential in investigating retinoid signaling pathways cellular proliferation apoptosis and antitumor mechanisms particularly in colorectal cancer models
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Medchemexpress LLC 2-amino-3-(naphthalen-1-yl)propanoic acid | 28095-56-9 | MFCD00067507 | 98.5% | 215.25 g/mol | C13H13NO2 | 100 G
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2-amino-3-(naphthalen-1-yl)propanoic acid is an alanine derivative bearing a naphthyl substituent on the beta carbon. It is supplied for research use and is used as an amino acid derivative and building block in biochemical and pharmacological studies. Handle with standard laboratory precautions and consult safety data before use.
- CAS number 28095-56-9.
- Molecular formula C13H13NO2.
- Molecular weight 215.25 g/mol.
- Purity 98.5%.
- Suitable as a building block in peptide and small-molecule synthesis.
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Medchemexpress LLC 2-amino-3-(naphthalen-1-yl)propanoic acid | 28095-56-9 | MFCD00067507 | 98.5% | 215.25 | C13H13NO2 | 5 G
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2-Amino-3-(naphthalen-1-yl)propanoic acid is an alanine-derived amino acid analogue supplied as a research reagent. It is used as a substituted amino acid probe in biochemical and pharmacological studies. The compound has documented molecular formula C13H13NO2 and molecular weight 215.25, is provided as a powder with specified purity, and includes datasheet and safety documentation for handling.
- Alanine-derived amino acid analogue for research applications.
- Molecular formula C13H13NO2, molecular weight 215.25.
- Purity 98.47%.
- Available in multiple package sizes including 5 g, 10 g, 25 g, 100 g.
- Powder storage: -20°C (up to 3 years) and 4°C (up to 2 years).
- In solvent storage: -80°C (up to 6 months) and -20°C (up to 1 month).
- Data sheet and SDS available for handling and safety information.
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![eMolecules Synthonix 1-Ethyl-3-methylimidazolium Acetate 100g 831794392 E38121 143314-17-4 [null] 170.212 C8H14N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694304.jpg-250.jpg)
eMolecules Synthonix 1-Ethyl-3-methylimidazolium Acetate 100g 831794392 E38121 143314-17-4 [null] 170.212 C8H14N2O2
Synthonix 1-Ethyl-3-methylimidazolium Acetate 100g 831794392 E38121 143314-17-4 [null] 170.212 C8H14N2O2
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Medchemexpress LLC Aceclidine hydrochloride | 6109-70-2 | 98.0% | 205.68 | 1 ML
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Aceclidine hydrochloride is a modulator of the M3 muscarinic acetylcholine receptor and acts as an M1 receptor agonist with an EC50 of 40 μM. It functions as a cycloplegic agent, a surfactant, a tonicity adjustor, and can optionally serve as a viscosity enhancer and an antioxidant. This compound holds potential for research into various disorders, including refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia.
- Modulator of M3 muscarinic acetylcholine receptor.
- M1 receptor agonist (EC50: 40 μM).
- Functions as a cycloplegic agent.
- Acts as a surfactant.
- Serves as a tonicity adjustor.
- Can optionally be a viscosity enhancer and an antioxidant.
- Potential for research in disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia.
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![eMolecules [4-Chloro-2-(trifluoromethyl)phenyl]zinc bromide, 0.5 M in THF | Synthonix |324.830 | C7H3BrClF3Zn | 0.000 | [Br-].FC(F)(F)c1cc(Cl)ccc1[Zn+] | 100ml | 812584968](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694425.jpg-250.jpg)
eMolecules [4-Chloro-2-(trifluoromethyl)phenyl]zinc bromide, 0.5 M in THF | Synthonix |324.830 | C7H3BrClF3Zn | 0.000 | [Br-].FC(F)(F)c1cc(Cl)ccc1[Zn+] | 100ml | 812584968
[4-Chloro-2-(trifluoromethyl)phenyl]zinc bromide, 0.5 M in THF | Synthonix |324.830 | C7H3BrClF3Zn | 0.000 | [Br-].FC(F)(F)c1cc(Cl)ccc1[Zn+] | 100ml | 812584968
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![eMolecules 352530-30-4 | 4-Iodobenzylzinc bromide, 0.50 M in THF | Synthonix | MFCD02260148 | 362.310 | C7H6BrIZn | 0.000 | [Br-].[Zn+]Cc1ccc(I)cc1 | 100ml | 532652876](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696116.jpg-250.jpg)
eMolecules 352530-30-4 | 4-Iodobenzylzinc bromide, 0.50 M in THF | Synthonix | MFCD02260148 | 362.310 | C7H6BrIZn | 0.000 | [Br-].[Zn+]Cc1ccc(I)cc1 | 100ml | 532652876
4-Iodobenzylzinc bromide, 0.50 M in THF | Synthonix | 352530-30-4 | MFCD02260148 | 362.310 | C7H6BrIZn | 0.000 | [Br-].[Zn+]Cc1ccc(I)cc1 | 100ml | 532652876
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Medchemexpress LLC BI-9627 (hydrochloride) | 1422252-46-7 | 98.0% | 392.80 | 1 ML
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BI-9627 hydrochloride is a potent and selective sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor, demonstrating over 30-fold selectivity against NHE2. It has been shown to decrease autophagy in HTR-8/SVneo cells, significantly reduce the pHi of human sperm, and prolong Ca2+ recovery time in KO hiPSC-CMs. This compound exhibits low drug-drug interaction potential, excellent pharmacokinetics in rat and dog models, and potent activity in isolated heart models of ischemia-reperfusion injury.
- Potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor
- Over 30-fold selectivity against NHE2
- Decreases autophagy in HTR-8/SVneo cells
- Significantly reduces pHi of human sperm
- Prolongs Ca2+ recovery time in KO hiPSC-CMs
- Low drug-drug interaction potential
- Excellent pharmacokinetics in rat and dog models
- Potent activity in isolated heart models of ischemia-reperfusion injury
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AdipoGen Trimethyl-4-sulfobutyl-indoliu
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Chemical. CAS 54136-26-4. Formula C15H21NO3S. MW 295.4. Synthetic. Building block for synthesis. Reagent used for electrophilic phenylation, e.g. of malonates and dithiocarboxylates.
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AdipoGen 6-Cl-2-OCH3-9-phenoxyacridine
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Chemical. CAS 7478-26-4. Formula C20H14ClNO2. MW 335.78. Synthetic. Acridine. Halogenated heterocycle used as building block.
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AdipoGen 5-Aminonicotinic acid
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Chemical. CAS 24242-19-1. Formula C6H6N2O2. MW 138.12. Synthetic. Building block for synthesis. Used in the synthesis of coordination polymers, bioluminescent reagents and biological active agents.
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TARGETMOL CHEMICALS INC BI-749327 1MG
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Also available in 1 mL, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6). Purity 99.68%
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AdipoGen 3-Phenyl-2-propynenitrile
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Chemical. CAS 935-02-4. Formula C9H5N. MW 127.14. Synthetic Cyanides/Nitriles. Organic building block for synthesis.
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AdipoGen 6-Cl-2-OCH3-9-phenoxyacridine
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Chemical. CAS 7478-26-4. Formula C20H14ClNO2. MW 335.78. Synthetic. Acridine. Halogenated heterocycle used as building block.
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Medchemexpress LLC Naphthol AS-E | 92-78-4 | MFCD00021639 | 98.0% | 297.74 | C17H12ClNO2 | 1 ML
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Naphthol AS-E is a small-molecule inhibitor of the KIX-KID interaction that directly binds the KIX domain of CREB-binding protein (CBP). It is supplied as a solid or as a ready-to-use 10 mM solution in DMSO and is used in biochemical and cell-based assays to probe KIX-KID-mediated interactions.
- Potent, cell-permeable inhibitor of the KIX-KID interaction.
- Directly binds the KIX domain of CBP (reported Kd ≈ 8.6 μM).
- Available as solid or 10 mM solution in DMSO for ready use.
- High purity suitable for research applications.
- Stable under recommended storage conditions for powder and in solvent.
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