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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000760027 4 4 -NAPHTHALENE-1 1G
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Aobchem AOBCHEM
5000916459 1-METHYL-2- 2-PROPEN-1-YLTHIO
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Medchemexpress LLC DYRKs-IN-1 hydrochloride | 1387090-01-8 | 1 ML
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DYRKs-IN-1 is a potent inhibitor of Dual-specificity tyrosine-phosphorylation-regulated kinases (DYRKs). This compound demonstrates antitumor activity, with IC50 values of 5 nM for DYRK1A and 8 nM for DYRK1B. The hydrochloride salt form offers enhanced water solubility and stability.
- Potent inhibitor of DYRK1A (IC50: 5 nM) and DYRK1B (IC50: 8 nM)
- Demonstrates antitumor activity
- Enhanced water solubility
- Increased stability
- Increases cellular potency against human colon tumor cell line SW 620 (EC50: 27 nM)
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Medchemexpress LLC Tizanidine (hydrochloride) | 64461-82-1 | 99.93 % | 1 ML
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Tizanidine hydrochloride is a skeletal muscle relaxant that acts as an orally effective central α2-adrenoceptor agonist. It primarily relaxes muscles by inhibiting the release of excitatory amino acids from spinal cord interneurons. Additionally, it exhibits anti-injury activity, can inhibit gastrointestinal (GI) transport, and has been shown to inhibit proliferation, migration, and invasion of lung cancer cells, inducing cell apoptosis. This compound is used to treat spasticity from conditions such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI).
- Skeletal muscle relaxant
- Central α2-adrenoceptor agonist
- Inhibits excitatory amino acid release
- Exhibits anti-injury activity
- Inhibits gastrointestinal (GI) transport
- Inhibits lung cancer cell proliferation, migration, and invasion
- Induces cell apoptosis
- Treats spasticity from multiple sclerosis, stroke, and spinal cord injury
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Medchemexpress LLC Moxonidine hydrochloride | 75536-04-8 | 99.8% | 1 ML
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Moxonidine hydrochloride | 75536-04-8 | 99.8% | 1 ML
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Medchemexpress LLC Naphthol AS-BI | 1237-75-8 | 99.9% | 100 MG
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Naphthol AS-BI is a substrate of β-glucuronidase and produces a bright red effect after staining biological tissues.
- For research use only.
- Not for sale to patients.
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Medchemexpress LLC Epirubicin hydrochloride | 56390-09-1 | 99.2% | 579.98 | 25 MG
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Epirubicin hydrochloride (4'-Epidoxorubicin hydrochloride) is a semisynthetic L-arabino derivative of doxorubicin. It acts as an antineoplastic agent by inhibiting Topoisomerase, and also inhibits DNA and RNA synthesis. Furthermore, it functions as a Forkhead box protein p3 (Foxp3) inhibitor, leading to the inhibition of regulatory T cell activity. This product is an analytical standard intended for research and analytical applications.
- Semisynthetic L-arabino derivative of doxorubicin
- Inhibits Topoisomerase
- Inhibits DNA and RNA synthesis
- Functions as a Forkhead box protein p3 (Foxp3) inhibitor
- Inhibits regulatory T cell activity
- Analytical standard for research and analytical applications
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Medchemexpress LLC BI-1808 10mg | 10mg
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BI-1808 is a human IgG1 monoclonal antibody that targets TNFR2by blocking interaction of TNFR2 with ligand TNF- confers Fc R-dependent depletion of Treg and mediates expansion of intratumoral CD8 T cells[1]
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Aobchem AOBCHEM
5000918651 4-ETHOXY- -DIMETHYL-1-NAPHTH
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Medchemexpress LLC Amiodarone hydrochloride | 19702-44-2 | MFCD00079083 | C25H30ClI2NO3 | 100 MG
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Amiodarone hydrochloride is a class III antiarrhythmic agent used in the treatment of various ventricular and supraventricular arrhythmias. It works by prolonging the action potential and refractory period in myocardial tissue.
- Acts as an antagonist at α1, β1, and β2 adrenoceptors
- Functions as a non-competitive antagonist at muscarinic receptors
- Blocks cardiac K+ channels and L-type Ca2+ channels
- Displays anti-anginal, anti-fibrillatory, and vasodilator effects
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Medchemexpress LLC Benzocaine hydrochloride | 23239-88-5 | MFCD00012999 | 201.65 | C9H12ClNO2 | 500mg
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Benzocaine (hydrochloride) is an orally active local agent that can suppress or relieve pain that acts on voltage-gated Na channels at a common receptor with an IC50 value of 0 8 mM at 30 mV Additionally Benzocaine (hydrochloride) non-competitively inhibits Ca-ATPase binding with Ca2 with an IC50 of 47 1 mM Benzocaine (hydrochloride) can be used in research within the field of neuromuscular regulation[1][2][3]
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Cambridge Isotope Laboratories VITAMIN K2 (MENAQUINONE MK-7) (4',5,6,7,8,8'-13C6, 99%) CHEM, 1 MG
VITAMIN K2 (MENAQUINONE MK-7) (4',5,6,7,8,8'-13C6, 99%) CHEM, 1 MG
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Medchemexpress LLC Revaprazan (hydrochloride) | 178307-42-1 | 25 MG
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Revaprazan hydrochloride is a reversible proton pump inhibitor that can inhibit gastric acid secretion and protect gastric mucosa. It can also inhibit IkappaB-alpha degradation and Akt inactivation, which attenuates H. pylori-induced COX-2 expression. This product can be used for research in infection and inflammation, including H. pylori-infected gastric inflammation and gastric ulcer.
- Reduces H. pylori-stimulated COX-2 expression and activity in AGS cells (5-20 μM, 24 h).
- Inhibits transcription activity of NF-κB in H. pylori-stimulated AGS cells (5-20 μM, 24 h).
- Improves the retarded cell growth in H. pylori-stimulated AGS cells (5-20 μM, 24 h).
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000784070 6-BROMO-2-NAPHTHOL 500G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000784073 THIOPHENE-3 4-DICARB 500G
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