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Filtered Search Results
AdipoGen 1-Pyrenecarboxaldehyde
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Chemical. CAS 3029-19-4. Formula C17H10O. MW 230.26. Synthetic. Building block for synthesis.
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AdipoGen N-Phenyl-benzimidoyl chloride
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Chemical. CAS 4903-36-0. Formula C13H10ClN. MW 215.68. Synthetic. Building block for synthesis.
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AdipoGen Methylbenzothiazol-2yl-aniline
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Chemical. CAS 92-36-4. Formula C14H12N2S. MW 240.33. Synthetic. Building block for synthesis.
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AdipoGen 1E-Iodo-hex-1-ene
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Chemical. CAS 16644-98-7. Formula C6H11I. MW 210.1. Synthetic. Building block for synthesis.
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AdipoGen E-8-Methyl-6-nonenoic acid
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Chemical. CAS 59320-77-3. Formula C10H18O2. MW 170.25. Synthetic Intermediate of the capsaicin biosynthesis. Fatty acid derivative from leucine/valine pathway. Plays a crucial role in determining the efficacy of capsaicin levels. The quantity of E-8-Methyl-6-nonenoic acid determines the pungency in placental tissues of Capsicum.
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![eMolecules 352525-72-5 | 4-Fluoro-3-methylphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01319871 | 301.410 | C7H6FIZn | 0.000 | [I-].Cc1cc([Zn+])ccc1F | 50ml | 532652843](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696148.jpg-250.jpg)
eMolecules 352525-72-5 | 4-Fluoro-3-methylphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01319871 | 301.410 | C7H6FIZn | 0.000 | [I-].Cc1cc([Zn+])ccc1F | 50ml | 532652843
4-Fluoro-3-methylphenylzinc iodide, 0.50 M in THF | Synthonix | 352525-72-5 | MFCD01319871 | 301.410 | C7H6FIZn | 0.000 | [I-].Cc1cc([Zn+])ccc1F | 50ml | 532652843
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![eMolecules 17318-03-5 | 3-Fluorophenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | MFCD00672007 | 199.305 | C6H4BrFMg | 0.000 | [Br-].Fc1cccc([Mg+])c1 | 500ml | 437237222](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697622.jpg-250.jpg)
eMolecules 17318-03-5 | 3-Fluorophenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | MFCD00672007 | 199.305 | C6H4BrFMg | 0.000 | [Br-].Fc1cccc([Mg+])c1 | 500ml | 437237222
3-Fluorophenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | 17318-03-5 | MFCD00672007 | 199.305 | C6H4BrFMg | 0.000 | [Br-].Fc1cccc([Mg+])c1 | 500ml | 437237222
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Medchemexpress LLC SBI-581 | 98.2% | 383.44 | 25 MG
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SBI-581 is an orally active and potent selective serine-threonine kinase TAO3 inhibitor with an IC50 of 42 nM. It promotes TKS5α accumulation at RAB11-positive vesicles and inhibits invadopodia formation. The compound demonstrates reasonable pharmacokinetics in mice and shows antitumor activity. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Orally active and potent selective serine-threonine kinase TAO3 inhibitor
- Promotes TKS5α accumulation at RAB11-positive vesicles
- Inhibits invadopodia formation
- Demonstrates reasonable pharmacokinetics in mice
- Shows antitumor activity
- Click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition
- Moderate selectivity against a broad panel of kinases
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![eMolecules 1034-49-7 | (Bromomethyl)triphenylphosphonium bromide | Combi-Blocks | MFCD00011864 | 436.127 | C19H17Br2P | 97.000 | [Br-].BrC[P+](c1ccccc1)(c1ccccc1)c1ccccc1 | 100g | 335351038](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697935.jpg-250.jpg)
eMolecules 1034-49-7 | (Bromomethyl)triphenylphosphonium bromide | Combi-Blocks | MFCD00011864 | 436.127 | C19H17Br2P | 97.000 | [Br-].BrC[P+](c1ccccc1)(c1ccccc1)c1ccccc1 | 100g | 335351038
(Bromomethyl)triphenylphosphonium bromide | Combi-Blocks | 1034-49-7 | MFCD00011864 | 436.127 | C19H17Br2P | 97.000 | [Br-].BrC[P+](c1ccccc1)(c1ccccc1)c1ccccc1 | 100g | 335351038
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![eMolecules 2259-30-5 | tert-Butylmagnesium bromide, 1.0 M in THF | Synthonix161.325 | C4H9BrMg | 0.000 | [Br-].CC(C)(C)[Mg+] | 50ml | 702445843](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695054.jpg-250.jpg)
eMolecules 2259-30-5 | tert-Butylmagnesium bromide, 1.0 M in THF | Synthonix161.325 | C4H9BrMg | 0.000 | [Br-].CC(C)(C)[Mg+] | 50ml | 702445843
tert-Butylmagnesium bromide, 1.0 M in THF | Synthonix | 2259-30-5161.325 | C4H9BrMg | 0.000 | [Br-].CC(C)(C)[Mg+] | 50ml | 702445843
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![eMolecules 1155294-76-0 | (9,9-Dimethylfluoren-2-yl)magnesium bromide, 0.5 M in THF | Synthonix297.478 | C15H13BrMg | 0.000 | [Br-].CC1(C)c2ccccc2-c2ccc([Mg+])cc12 | 50ml | 812584969](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694424.jpg-250.jpg)
eMolecules 1155294-76-0 | (9,9-Dimethylfluoren-2-yl)magnesium bromide, 0.5 M in THF | Synthonix297.478 | C15H13BrMg | 0.000 | [Br-].CC1(C)c2ccccc2-c2ccc([Mg+])cc12 | 50ml | 812584969
(9,9-Dimethylfluoren-2-yl)magnesium bromide, 0.5 M in THF | Synthonix | 1155294-76-0297.478 | C15H13BrMg | 0.000 | [Br-].CC1(C)c2ccccc2-c2ccc([Mg+])cc12 | 50ml | 812584969
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![eMolecules 92273-73-9 | Butylzinc bromide, 0.50 M in THF | Synthonix | MFCD00671997 | 202.400 | C4H9BrZn | 0.000 | [Br-].CCCC[Zn+] | 100ml | 627353799](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695217.jpg-250.jpg)
eMolecules 92273-73-9 | Butylzinc bromide, 0.50 M in THF | Synthonix | MFCD00671997 | 202.400 | C4H9BrZn | 0.000 | [Br-].CCCC[Zn+] | 100ml | 627353799
Butylzinc bromide, 0.50 M in THF | Synthonix | 92273-73-9 | MFCD00671997 | 202.400 | C4H9BrZn | 0.000 | [Br-].CCCC[Zn+] | 100ml | 627353799
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Aobchem 2-Bromo-1-naphthalenol | ≥97% | CAS 771-15-3 | C10H7BrO | 5g
2-Bromo-1-naphthalenol | ≥97% | CAS 771-15-3 | C10H7BrO | 5g
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Medchemexpress LLC Buparlisib Hydrochloride | 1312445-63-8 | C18H22ClF3N6O2 | 100 MG
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Buparlisib Hydrochloride (BKM120 Hydrochloride) is a CNS-penetrant pan-class I PI3K inhibitor. It demonstrates IC50 values of 52 nM for p110α, 166 nM for p110β, 116 nM for p110δ, and 262 nM for p110γ.
- Exhibits activity between 50-300 nM for class I PI3K's, including common p110α mutants.
- Shows lower potency against class III and class IV PI3K's such as VPS34, mTOR, DNAPK, and PI4K.
- Induces multiple myeloma (MM) cell apoptosis in a dose- and time-dependent manner.
- Causes dose-dependent growth inhibition in various MM cell lines.
- In A2780 xenograft tumors, oral dosing leads to dose-dependent modulation of pAKTSer473.
- Inhibition of pAKT (normalized to total AKT) correlates well with both plasma and tumor drug exposure.
- Significantly reduces tumor burdens and prolongs the survival of tumor-bearing mice.
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![eMolecules 50777-51-0 | 3-Ethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock209.369 | C8H9BrMg | 0.000 | [Br-].CCc1cccc([Mg+])c1 | 100ml | 437237186](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697647.jpg-250.jpg)
eMolecules 50777-51-0 | 3-Ethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock209.369 | C8H9BrMg | 0.000 | [Br-].CCc1cccc([Mg+])c1 | 100ml | 437237186
3-Ethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 50777-51-0209.369 | C8H9BrMg | 0.000 | [Br-].CCc1cccc([Mg+])c1 | 100ml | 437237186
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