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Filtered Search Results
Medchemexpress LLC 1-hydroxy-2-naphthoic acid | 86-48-6 | MFCD00003960 | 99.6% | 188.18 g/mol | C11H8O3 | 100 G
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1-Hydroxy-2-naphthoic acid is an aromatic carboxylic acid supplied as a solid for use as a reagent, analytical standard, or reference material in chemical research and analysis. It is commonly used in chromatographic and spectroscopic method development and as a degradation intermediate reference for polycyclic aromatic hydrocarbons.
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Medchemexpress LLC Paroxetine (hydrochloride) | 78246-49-8 | 99.98% | 365.83 | 500 MG
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Paroxetine hydrochloride is a potent selective serotonin-reuptake inhibitor (SSRI), also known as a GRK2 inhibitor with an IC50 of 14 μM. It is commonly used for the research of depressive disorder.
- Potent selective serotonin-reuptake inhibitor
- GRK2 inhibitor with IC50 of 14 μM
- Used for research of depressive disorder
- Available in solid and solution forms
- High purity of 99.98%
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![eMolecules 282727-19-9 | 2-Ethylphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01311456 | 297.440 | C8H9IZn | 0.000 | [I-].CCc1ccccc1[Zn+] | 100ml | 532652810](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696179.jpg-250.jpg)
eMolecules 282727-19-9 | 2-Ethylphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01311456 | 297.440 | C8H9IZn | 0.000 | [I-].CCc1ccccc1[Zn+] | 100ml | 532652810
2-Ethylphenylzinc iodide, 0.50 M in THF | Synthonix | 282727-19-9 | MFCD01311456 | 297.440 | C8H9IZn | 0.000 | [I-].CCc1ccccc1[Zn+] | 100ml | 532652810
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![Medchemexpress LLC Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-, sodium salt, (E)- | 115103-85-0 | 99.8% | 537.07 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000404868-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-, sodium salt, (E)- | 115103-85-0 | 99.8% | 537.07 | 1 ML
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MK-571 sodium is an orally active, potent, and selective competitive leukotriene D4 (LTD4) receptor antagonist. It has Ki values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. It also acts as an inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1), and inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release.
- Orally active
- Potent and selective competitive leukotriene D4 (LTD4) receptor antagonist
- Inhibits multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1)
- Inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release
- Available for research use only
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eMolecules Ambeed / Tetrakis(decyl)ammonium bromide / 1g / 570568805 / A248667 / / 14937-42-9 / MFCD00043166 / 659.023 / C40H84BrN
Ambeed / Tetrakis(decyl)ammonium bromide / 1g / 570568805 / A248667 / / 14937-42-9 / MFCD00043166 / 659.023 / C40H84BrN
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Medchemexpress LLC Imipramine hydrochloride | 113-52-0 | MFCD00012669 | 99.85% | 1 ML
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Imipramine hydrochloride is an orally active tertiary amine tricyclic antidepressant. It acts as a Fascin1 inhibitor with antitumor activities and also inhibits the serotonin transporter with an IC50 value of 32 nM. This compound stimulates autophagy in U-87MG glioma cells and induces apoptosis in HL-60 cells. Additionally, it exhibits neuroprotective and immunomodulatory effects.
- Orally active tertiary amine tricyclic antidepressant.
- Fascin1 inhibitor with antitumor activities.
- Inhibits serotonin transporter (IC50 value of 32 nM).
- Stimulates U-87MG glioma cells autophagy.
- Induces HL-60 cell apoptosis.
- Shows neuroprotective effects.
- Exhibits immunomodulatory effects.
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![eMolecules 480438-47-9 | 4-Chloro-2-methylphenylmagnesium bromide, 0.50 M in THF | Synthonix - Stock | MFCD02260215 | 229.780 | C7H6BrClMg | 0.000 | [Br-].Cc1cc(Cl)ccc1[Mg+] | 500ml | 437237039](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697745.jpg-250.jpg)
eMolecules 480438-47-9 | 4-Chloro-2-methylphenylmagnesium bromide, 0.50 M in THF | Synthonix - Stock | MFCD02260215 | 229.780 | C7H6BrClMg | 0.000 | [Br-].Cc1cc(Cl)ccc1[Mg+] | 500ml | 437237039
4-Chloro-2-methylphenylmagnesium bromide, 0.50 M in THF | Synthonix - Stock | 480438-47-9 | MFCD02260215 | 229.780 | C7H6BrClMg | 0.000 | [Br-].Cc1cc(Cl)ccc1[Mg+] | 500ml | 437237039
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![eMolecules 402-51-7 | (4-(Trifluoromethyl)phenyl)magnesium bromide, 0.25 M in THF | Synthonix - Stock | MFCD00672011 | 249.313 | C7H4BrF3Mg | 97.000 | [Br-].FC(F)(F)c1ccc([Mg+])cc1 | 50ml | 348890464](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697892.jpg-250.jpg)
eMolecules 402-51-7 | (4-(Trifluoromethyl)phenyl)magnesium bromide, 0.25 M in THF | Synthonix - Stock | MFCD00672011 | 249.313 | C7H4BrF3Mg | 97.000 | [Br-].FC(F)(F)c1ccc([Mg+])cc1 | 50ml | 348890464
(4-(Trifluoromethyl)phenyl)magnesium bromide, 0.25 M in THF | Synthonix - Stock | 402-51-7 | MFCD00672011 | 249.313 | C7H4BrF3Mg | 97.000 | [Br-].FC(F)(F)c1ccc([Mg+])cc1 | 50ml | 348890464
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Medchemexpress LLC Antazoline hydrochloride | 2508-72-7 | 99.6% | 500 MG
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Antazoline hydrochloride | 2508-72-7 | 99.6% | 500 MG
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Medchemexpress LLC Epirubicin hydrochloride | 56390-09-1 | >99.2% | 579.98 | 100 MG
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Epirubicin hydrochloride is a semisynthetic L-arabino derivative of doxorubicin, functioning as an antineoplastic agent by inhibiting Topoisomerase and DNA/RNA synthesis. It also acts as a Forkhead box protein p3 (Foxp3) inhibitor, suppressing regulatory T cell activity. Its antitumor effects involve forming a complex with DNA, causing damage and interfering with essential synthesis processes.
- Acts as an antineoplastic agent.
- Inhibits Topoisomerase, DNA, and RNA synthesis.
- Functions as a Forkhead box protein p3 (Foxp3) inhibitor.
- Suppresses regulatory T cell activity.
- Causes DNA damage by complexing with DNA.
- Cytotoxic to various cancer cells, including Hepatoma G2 cells (IC50 1.6 μg/mL).
- Induces apoptosis and alters antioxidant enzyme activity in Hep G2 cells.
- Clinically active against a wide range of tumor types.
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AdipoGen 5-Aminolevulinic acid HCl
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Chemical. CAS 5451-09-2. Formula C5H9NO3 . HCl. MW 131.13 . 36.46. 5-Aminolevulinic acid 5-ALA is a non-proteinogenic five carbon amino acid, which is the precursor for the biosynthesis of tetrapyrrole compounds, such as heme, chlorophyll and vitamin B12 and has broad applications in the medical and agricultural fields. The conversion of 5-ALA to protoporphyrins within tissues produces a photosensitive target that produces reactive oxygen species upon exposure to light. In this way, it is used in photodynamic therapy for a range of dermatological conditions, cancers, and other diseases. Oral administration of 5-ALA leads to the preferential accumulation of the fluorescent molecule protoporphyrin IX within certain types of cancer cells. This allows fluorescence-based identification of tumor tissue for accurate resection of diseased tissue.
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Medchemexpress LLC BI-3231 | 2894848-07-6 | 99.8% | 380.37 | 500 MG
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BI-3231 is a chemical probe that functions as a potent and selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13). It exhibits IC50 values of 1 nM for human HSD17B13 and 13 nM for mouse HSD17B13. This compound holds potential for research into nonalcoholic steatohepatitis (NASH) and various other liver diseases. The BI-3231 probe was developed by Boehringer Ingelheim and is available for free through their open innovation portal, opnMe.com, alongside its negative control.
- Potent and selective HSD17B13 inhibitor.
- IC50 values: 1 nM (hHSD17B13) and 13 nM (mHSD17B13).
- Potential for research in nonalcoholic steatohepatitis (NASH) and liver diseases.
- High metabolic stability in liver microsomes.
- Moderate metabolic stability in hepatocytes.
- Rapidly cleared from plasma, with considerable hepatic exposure maintained over 48 hours in vivo.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000784183 NAPHTHALENE-1 4-DICA 25G
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Aobchem AOBCHEM
5001069868 -2-PROPEN-1-YLBENZENEACETONIT
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Aobchem AOBCHEM
5001069911 -2-PROPEN-1-YLBENZENEACETONIT
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