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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Menadione United States Pharmacopeia (USP) Reference Standard | 58-27-5 | MFCD00001681 | 200MG
Menadione United States Pharmacopeia (USP) Reference Standard | Mol Wt: 172.18 | 58-27-5 | MFCD00001681 | 200MG
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Apexbio Technology LLC Naphthol AS-MX phosphate 1596-56-1 50mg
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Naphthol AS-MX phosphate (CAS 1596-56-1) is a small molecule inhibitor that disrupts the interaction between cAMP response element-binding protein (CREB) and CREB-binding protein (CBP) key components of a transcription factor complex In lung cancer cells it demonstrates antiproliferative effects as evidenced by an IC50 of 3 701 mol/L and inhibits both colony formation and anchorage-independent growth Naphthol AS-MX phosphate is utilized in studies investigating KRAS-mutant lung cancers particularly in the context of chemoresistance and poor prognosis
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Medchemexpress LLC Givinostat hydrochloride monohydrate | 732302-99-7 | 99.6% | 475.97 | 25 MG
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Givinostat hydrochloride monohydrate is a potent HDAC inhibitor, demonstrating IC50 values of 198 nM for HDAC1 and 157 nM for HDAC3. This compound is notable for its ability to penetrate the blood-brain barrier, making it suitable for a range of research applications.
- Potent HDAC inhibitor for HDAC1 and HDAC3
- Penetrates the blood-brain barrier
- Suppresses LPS-induced IL-1β and IL-6 production
- Inhibits JS-1 cell proliferation
- Reduces serum TNFα and IL-1β levels in vivo
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eMolecules 54806-25-6 | Ambeed | Naphthalen-1-ylbis(triphenylphosphoranyl)nickel(IV) chloride | 100mg | 633417948 | A111417 | 745.89 | C46H37ClNiP2
Ambeed | Naphthalen-1-ylbis(triphenylphosphoranyl)nickel(IV) chloride | 100mg | 633417948 | A111417 | 54806-25-6 | 745.890 | C46H37ClNiP2
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U.S. Pharmacopeia Menadione | 58-27-5 | MFCD00001681 | 200 mg
Menadione | Mol Wt: 172.18 | 58-27-5 | MFCD00001681 | 200 mg
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eMolecules 883-62-5 | 3-METHOXY-2-NAPHTHOIC ACID | AstaTech | MFCD00094168 | 202.209 | C12H10O3 | 95.000 | COc1cc2ccccc2cc1C(O)=O | 1g | 402180737
3-METHOXY-2-NAPHTHOIC ACID | AstaTech | 883-62-5 | MFCD00094168 | 202.209 | C12H10O3 | 95.000 | COc1cc2ccccc2cc1C(O)=O | 1g | 402180737
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Medchemexpress LLC Varenicline hydrochloride | 230615-23-3 | 99.9% | 247.72 g/mol | C13H14ClN3 | 100 MG
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Varenicline hydrochloride is the hydrochloride salt of varenicline, an orally active partial agonist of α4β2 nicotinic acetylcholine receptors used in neuroscience and pharmacology research. It is provided for research and analytical applications in solid form and as prepared solutions for in vitro studies and assay development.
- Partial agonist at α4β2 nicotinic acetylcholine receptors, useful for receptor pharmacology studies.
- Supplied as a powder and in solution formats for flexible assay preparation.
- High purity suitable for analytical and biological assays.
- Characterized with confirmed CAS number and molecular weight for chemical identification.
- Suitable for use in studies of nicotine dependence and neuromodulation pathways.
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Medchemexpress LLC Migalastat (hydrochloride) | 75172-81-5 | 99.7% | 199.63 | 25 MG
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Migalastat hydrochloride (GR181413A) is an orally active α-galactosidase A molecular chaperone. It binds to the active site of unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. Upon dissociation in the acidic environment, Migalastat enables these mutant enzymes to regain biological activity. It exhibits an IC50 and Ki value of 0.04 μM for human α-Gal A.
- Orally active α-galactosidase A molecular chaperone
- IC50 and Ki of 0.04 μM for human α-Gal A
- Facilitates transport and restores activity of mutant α-galactosidase A enzymes
- Reduces Gb3 accumulation and lysosome volume in vitro
- Increases α-Gal A activity in heart, kidney, spleen, and liver in transgenic mice
- Reduces lyso-Gb3 levels in kidney, heart, and skin in transgenic mice
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Medchemexpress LLC BI-0474 | 2750570-55-7 | 99.8% | 587.74 | 100 MG
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BI-0474 is a potent KRASG12C inhibitor with an IC50 value of 7.0 nM for the GDP-KRAS::SOS1 protein-protein interaction. It demonstrates significant anti-proliferative activity against NCI-H358 cells carrying the G12C mutation and shows favorable anti-tumor activity in non-small cell lung cancer xenograft models.
- Potent KRASG12C inhibitor
- Inhibits GDP-KRAS::SOS1 protein-protein interaction with an IC50 of 7.0 nM
- Exhibits anti-proliferative activity against NCI-H358 cells with G12C mutation
- Shows anti-tumor activity in non-small cell lung cancer xenograft models
- Induces programmed cell death in xenograft models
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Aobchem AOBCHEM
5000864867 6-BROMO-1-CHLORO-2-NAPHTHOL 1G
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Aobchem AOBCHEM
5000864868 6-BROMO-1-CHLORO-2-NAPHTHOL 25
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eMolecules 135-07-9 | Medchem Express | Methyclothiazide | 10mg | 527573895 | HY-B0562 | MFCD00242610 | 360.22 | C9H11Cl2N3O4S2
ChemScene | 2-(Propylamino)ethanol | 10g | 569146232 | CS-0105782 | 16369-21-4 | MFCD00002844 | 103.165 | C5H13NO
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000703253 BI-69A11 10MG
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Medchemexpress LLC (R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide | 1005450-55-4 | 99.05% | C22H20F3NO | 5 G
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This compound is a drug intermediate used for the synthesis of various active compounds. It is intended for research use only and not sold to patients.
- Appearance: Solid, white to off-white
- Purity: 99.05%
- Storage conditions: 4°C, sealed storage, away from moisture
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Ambeed AMBEED
5000868094 1-AMINO-2-NAPHTHOIC ACID 1GR
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