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Filtered Search Results
![Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]meth | 1093108-50-9 | 99.4% | 501.50 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436764-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]meth | 1093108-50-9 | 99.4% | 501.50 | 1 MG
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BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). It has IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. This compound shows potential for the treatment of poorly controlled asthma.
- Highly specific and potent antagonist of DP2/CRTH2
- Potential for treating poorly controlled asthma
- Exhibits low nM potency against human or mouse CRTH2 in transfected cells
- Significantly inhibits AHR in mice
- Effectively blocks edema formation and reduces inflammatory infiltrate and skin pathology in drug vehicle-treated animals
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![eMolecules 312693-02-0 | 2-Ethylbutylzinc bromide, 0.50 M in THF | Synthonix | MFCD01311415 | 230.450 | C6H13BrZn | 0.000 | [Br-].CCC(CC)C[Zn+] | 50ml | 532652805](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696184.jpg-250.jpg)
eMolecules 312693-02-0 | 2-Ethylbutylzinc bromide, 0.50 M in THF | Synthonix | MFCD01311415 | 230.450 | C6H13BrZn | 0.000 | [Br-].CCC(CC)C[Zn+] | 50ml | 532652805
2-Ethylbutylzinc bromide, 0.50 M in THF | Synthonix | 312693-02-0 | MFCD01311415 | 230.450 | C6H13BrZn | 0.000 | [Br-].CCC(CC)C[Zn+] | 50ml | 532652805
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(CCCC)c1ccnc(SC)n1 | 5g | 525920340](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696741.jpg-250.jpg)
eMolecules 123061-49-4 | 2-(Methylthio)-4-(tributylstannyl)pyrimidine | Synthonix - Stock | MFCD01319026 | 415.230 | C17H32N2SSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccnc(SC)n1 | 5g | 525920340
2-(Methylthio)-4-(tributylstannyl)pyrimidine | Synthonix - Stock | 123061-49-4 | MFCD01319026 | 415.230 | C17H32N2SSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccnc(SC)n1 | 5g | 525920340
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(CCCC)\C=C\C | 5g | 525924262](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696531.jpg-250.jpg)
eMolecules 105494-65-3 | Tri-n-butyl(1-propenyl)tin E and Z | Synthonix - Stock | MFCD03425868 | 331.131 | C15H32Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)\C=C\C | 5g | 525924262
Tri-n-butyl(1-propenyl)tin E and Z | Synthonix - Stock | 105494-65-3 | MFCD03425868 | 331.131 | C15H32Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)\C=C\C | 5g | 525924262
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Medchemexpress LLC NNC 05-2090 hydrochloride | 184845-18-9 | MFCD00952020 | 99.1% | 451.00 g/mol | C27H31ClN2O2 | 100 MG
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NNC 05-2090 hydrochloride is a research compound that inhibits GABA uptake and selectively inhibits the mGAT2 (BGT-1) transporter. It exhibits anticonvulsant activity and is used in preclinical studies of epilepsy and other neurological disorders.
- GABA uptake inhibitor and selective mGAT2 (BGT-1) inhibitor (Ki ≈ 1.4 μM).
- Demonstrated anticonvulsant activity; used in preclinical epilepsy research.
- Supplied as the hydrochloride salt with molecular formula C27H31ClN2O2.
- High purity (99.1% by HPLC) suitable for biochemical and pharmacological studies.
- Available in multiple pack sizes and as a 10 mM solution in DMSO for in vitro use.
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Medchemexpress LLC Siglec-10 Human Bi 50ug | 50ug
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Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding preferentially selecting -2 3- or -2 6-linked sialic acid Its sialic acid recognition site may be masked by cis interactions Siglec-10 Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived Siglec-10 protein expressed by HEK293 with C-Avi C-His labeled tag
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Apexbio Technology LLC BI 6015 93987-29-2 5mg
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BI 6015 is a small-molecule antagonist targeting hepatocyte nuclear factor 4 alpha (HNF4 ) a nuclear receptor implicated in transcriptional regulation within liver intestinal and pancreatic -cells It is designed to inhibit HNF4 -mediated transcriptional activation thereby modulating gene expression related to glucose and lipid metabolism BI 6015 exerts its biological activity primarily through direct antagonism of HNF4 leading to reduced transcriptional activation and lowering endogenous HNF4 protein levels In cell-based studies BI 6015 demonstrates inhibition of insulin promoter activity and suppression of endogenous insulin expression in T6PNE cells as well as decreased HNF4 protein in MIN6 and HepG2 cells Based on these pharmacological properties BI 6015 holds research potential in the study of diabetes and hepatic metabolic regulation
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Apexbio Technology LLC BI 2536(Synonyms: BI-2536, BI2536, Plk1 inhibitor BI 2536), 10mg, CAS: 755038-02-9.
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BI 2536 (CAS number 755038-02-9) is an ATP-competitive inhibitor selectively targeting human polo-like kinase 1 (PLK1) exhibiting an IC50 value of approximately 0 83 nM Comparatively BI 2536 shows substantially less affinity towards other kinases In vitro studies demonstrate that BI 2536 inhibits proliferation of various human tumor cell lines (EC50 values ranging from 2 to 25 nM) and induces G2/M cell cycle arrest accompanied by apoptosis as evidenced in HeLa cervical cancer cells In vivo data from xenograft tumor models indicate that BI 2536 administered intravenously on a weekly or biweekly schedule possesses antitumor efficacy
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![eMolecules Synthonix (5-Fluoropentyl)magnesium bromide 0.50 M in THF 50ml 702445902 F73631 1465906-89-1 [null] 193.342 C5H10BrFMg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694998.jpg-250.jpg)
eMolecules Synthonix (5-Fluoropentyl)magnesium bromide 0.50 M in THF 50ml 702445902 F73631 1465906-89-1 [null] 193.342 C5H10BrFMg
Synthonix (5-Fluoropentyl)magnesium bromide 0.50 M in THF 50ml 702445902 F73631 1465906-89-1 [null] 193.342 C5H10BrFMg
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Ambeed 1 6Dihydroxynaphthalene
1,6-Dihydroxynaphthalene, 575-44-0, 97%
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Selleck Chemical LLC BI-0474-E1356-100MG
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BI-0474 is a potent inhibitor of KRASG12C with an IC50 value of 7 0 nM It inhibits GDP-KRAS SOS1 protein-protein interactions It exhibits anti-proliferative and anti-tumour activity and can be used in cancer research
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![eMolecules 2765568-21-4 | 2-Methyl-4-pyridylmagnesium bromide, 0.25 M in THF | Synthonix196.330 | C6H6BrMgN | 0.000 | [Br-].Cc1cc([Mg+])ccn1 | 100ml | 702445936](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694970.jpg-250.jpg)
eMolecules 2765568-21-4 | 2-Methyl-4-pyridylmagnesium bromide, 0.25 M in THF | Synthonix196.330 | C6H6BrMgN | 0.000 | [Br-].Cc1cc([Mg+])ccn1 | 100ml | 702445936
2-Methyl-4-pyridylmagnesium bromide, 0.25 M in THF | Synthonix | 2765568-21-4196.330 | C6H6BrMgN | 0.000 | [Br-].Cc1cc([Mg+])ccn1 | 100ml | 702445936
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![eMolecules 737797-10-3 | 1-Hexadecylzinc bromide, 0.50 M in THF | Synthonix370.720 | C16H33BrZn | 0.000 | [Br-].CCCCCCCCCCCCCCCC[Zn+] | 100ml | 532652858](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696133.jpg-250.jpg)
eMolecules 737797-10-3 | 1-Hexadecylzinc bromide, 0.50 M in THF | Synthonix370.720 | C16H33BrZn | 0.000 | [Br-].CCCCCCCCCCCCCCCC[Zn+] | 100ml | 532652858
1-Hexadecylzinc bromide, 0.50 M in THF | Synthonix | 737797-10-3370.720 | C16H33BrZn | 0.000 | [Br-].CCCCCCCCCCCCCCCC[Zn+] | 100ml | 532652858
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![eMolecules 138084-62-5 | [3-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopent-1-yl)propyl]magnesium bromide, 0.5M in THF | Synthonix304.661 | C9H22BrMgNSi2 | 95.000 | [Br-].C[Si]1(C)CC[Si](C)(C)N1CCC[Mg+] | 25ml | 794559324](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694612.jpg-250.jpg)
eMolecules 138084-62-5 | [3-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopent-1-yl)propyl]magnesium bromide, 0.5M in THF | Synthonix304.661 | C9H22BrMgNSi2 | 95.000 | [Br-].C[Si]1(C)CC[Si](C)(C)N1CCC[Mg+] | 25ml | 794559324
[3-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopent-1-yl)propyl]magnesium bromide, 0.5M in THF | Synthonix | 138084-62-5304.661 | C9H22BrMgNSi2 | 95.000 | [Br-].C[Si]1(C)CC[Si](C)(C)N1CCC[Mg+] | 25ml | 794559324
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Selleck Chemical LLC BI-847325
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BI-847325 is an orally bioavailable and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM 25 nM 15 nM 25 nM and 4 nM for Xenopus laevis Aurora B human Aurora A and Aurora C as well as human MEK1 and MEK2 respectively Phase 1
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