Unsaturated hydrocarbons
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- (10)
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Filtered Search Results
eMolecules PHENYLACETYLENE 25G
5000189456 PHENYLACETYLENE 25G
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eMolecules PHENYLACETYLENE 250G
5000189458 PHENYLACETYLENE 250G
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eMolecules PHENYLACETYLENE 100G
5000224175 PHENYLACETYLENE 100G
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eMolecules PHENYLACETYLENE 25G
5000224179 PHENYLACETYLENE 25G
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eMolecules PHENYLACETYLENE 5G
5000224645 PHENYLACETYLENE 5G
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eMolecules EMOLECULES INC
5000483729 PHENYLACETYLENE 500G
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eMolecules ChemScene / Pyridine-246-tricarboxylic acid / 100mg / 718356514 / CS-0111100 / 0.000 / 536-20-9 / MFCD00778565 / 211.129 / C8H5NO6
ChemScene / Pyridine-246-tricarboxylic acid / 100mg / 718356514 / CS-0111100 / 0.000 / 536-20-9 / MFCD00778565 / 211.129 / C8H5NO6
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eMolecules 1-Phenyl-1-hexyne | 1129-65-3 | 1G | Purity: 98%
Combi-Blocks | 1-Phenyl-1-hexyne | 1G | 1129-65-3 | MFCD00039969
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eMolecules Chem-Impex Phenylacetylene 1kg 342449724 24540 0 000 MFCD00008570 102 136 C8H6
Chem-Impex Phenylacetylene 1kg 342449724 24540 0 000 MFCD00008570 102 136 C8H6
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Medchemexpress LLC DJ-V-159 | 2253744-53-3 | 99.9% | 502.37 | 50 MG
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DJ-V-159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A). It activates ERK in HEK-293 cells transfected with GPRC6A and dose-dependently stimulates cAMP production. DJ-V-159 also stimulates insulin secretion in mouse beta-cell MIN-6 cells, similar to the effects of Ocn, a known ligand of GPRC6A, and has been shown to reduce blood glucose levels in wildtype mice.
- Activates ERK in HEK-293 cells transfected with GPRC6A.
- Stimulates cAMP production in GPRC6A expressing HEK-293 cells.
- Stimulates insulin secretion in mouse beta-cell MIN-6 cells.
- Reduces blood glucose levels in wildtype mice.
- For research use only.
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Selleck Chemical LLC ETC-159
ETC-159 (ETC-1922159) is an orally available potent porcupine inhibitor with an IC50 of 2 9 nM for inhibiting -catenin reporter activity in STF3A cells
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Medchemexpress LLC ETC-159 | 1638250-96-0 | 99.1% | 391.38 | 100 MG
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ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM. ETC-159 blocks the secretion and activity of all Wnts and shows robust activity in multiple cancer models driven by high Wnt signaling. It is highly efficacious in molecularly defined colorectal cancers (CRCs) with R-spondin translocations.
- Potent, orally available PORCN inhibitor.
- Inhibits β-catenin reporter activity with an IC50 of 2.9 nM.
- Blocks the secretion and activity of all Wnts.
- Exhibits robust activity in various cancer models driven by high Wnt signaling.
- Highly efficacious in colorectal cancers (CRCs) with R-spondin translocations.
- Inhibits mouse PORCN with an IC50 of 18.1 nM.
- Demonstrates good oral pharmacokinetics in mice with 100% oral bioavailability after a single oral dose of 5 mg/kg.
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![Medchemexpress LLC Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl)amino]-N-methyl- | 1513879-21-4 | 99.9% | 352.39 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385930-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl)amino]-N-methyl- | 1513879-21-4 | 99.9% | 352.39 | 25 MG
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BQR-695 is a PI4KIIIβ inhibitor with IC50s of 80 nM for human PI4KIIIβ and 3.5 nM for the *Plasmodium* variant of PI4KIIIβ. For research use only.
- Treatment with 0.5 μM of either KAI407 or BQR695 causes GFP-PHOsh2 to redistribute to the parasite plasma membrane, consistent with depletion of intracellular PI4P upon inhibition of PfPI4K function.
- BQR695 shows no evidence of toxicity against mature red blood cells (RBCs).
- It induces a schizont-stage arrest indistinguishable from that observed in imidazopyrazine-treated parasites and exhibits cross-resistance with the imidazopyrazine-resistant lines.
- DMSO: 50 mg/mL (141.89 mM; requires ultrasonic; hygroscopic DMSO has a significant impact on solubility, use newly opened DMSO).
- Powder: -20°C for 3 years, 4°C for 2 years.
- In solvent: -80°C for 2 years, -20°C for 1 year.
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![Medchemexpress LLC Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl)amino]-N-methyl- | 1513879-21-4 | 99.9% | 352.39 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387916-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl)amino]-N-methyl- | 1513879-21-4 | 99.9% | 352.39 | 5 MG
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BQR-695 is a PI4KIIIβ inhibitor, active against both human and *Plasmodium* variants of PI4KIIIβ. It effectively inhibits PI4KIIIβ function, leading to depletion of intracellular PI4P, and shows no toxicity against mature red blood cells. It induces schizont-stage arrest and exhibits cross-resistance with imidazopyrazine-resistant lines.
- Inhibits human PI4KIIIβ with an IC50 of 80 nM
- Inhibits *Plasmodium* PI4KIIIβ with an IC50 of 3.5 nM
- Causes GFP-PHOsh2 to redistribute to parasite plasma membrane
- No toxicity against mature red blood cells
- Induces schizont-stage arrest
- Exhibits cross-resistance with imidazopyrazine-resistant lines
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Medchemexpress LLC Ovalbumin (154-159) | 1370698-94-4 | 99.9% | 672.77 | 1 MG
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Ovalbumin (154-159) | 1370698-94-4 | 99.9% | 672.77 | 1 MG
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