Cyclopropanecarboxylic acids and derivatives
Medchemexpress LLC 4-hydroperoxy cyclophosphamide | 39800-16-3 | MFCD01710226 | >98.0% | 293.08 g/mol | C7H15Cl2N2O4P | 25 MG
4-Hydroperoxy cyclophosphamide is the active metabolite of cyclophosphamide and is used as a research reagent to study DNA crosslinking, cytotoxic mechanisms, and immune-cell apoptosis. It is supplied as a dry solid for laboratory use and requires low-temperature storage to maintain stability in storage and handling.
- active metabolite used in cytotoxicity and immunology studies.
- cross-links DNA and induces T-cell apoptosis.
- high purity: >98.0% (HPLC) as reported by analytical sources.
- molecular weight 293.08 g/mol and formula C7H15Cl2N2O4P.
- soluble in DMSO at 50 mg/mL; sonication may be required.
- store at -20°C under nitrogen; in solvent store at -80°C for long-term stability.
Medchemexpress LLC 4-hydroperoxy cyclophosphamide | 39800-16-3 | MFCD01710226 | ≥98.0% | 293.08 | C7H15Cl2N2O4P | 1 MG
4-hydroperoxy cyclophosphamide is the active metabolite of cyclophosphamide and functions as a DNA alkylator/crosslinker that induces T-cell apoptosis and produces reactive oxygen species. It is used as a research reagent to study DNA damage, apoptosis pathways, and immune modulation in vitro and in vivo.
- Active DNA crosslinker inducing apoptosis independent of death-receptor activation.
- Useful for studying apoptosis, immune cell depletion, and autoimmune disease models.
- Supplied in small mass formats suitable for stock solution preparation, including 1 mg quantities.
- Stable when stored under nitrogen at -20°C; in solvent stable at -80°C for up to 6 months.
- High purity (≥98.0%) suitable for biochemical and cellular assays.
Medchemexpress LLC VH032-cyclopropane-F | 2306193-99-5 | 99.92% | 532.63 | 250 MG
VH032-cyclopropane-F is a VHL ligand based on VH032. It can be linked to other protein ligands (e.g., SMARCA BD ligand) via a linker to create PROTACs (e.g., PROTAC 1). PROTAC 1 functions as a partial degrader of SMARCA2 and SMARCA4.
- Is a VH032-based VHL ligand.
- Can be connected to other protein ligands to form PROTACs.
- Increases FAK expression levels in A427 cells at 5 μM for 24 hours.
- Available in solid and solution forms.
- High purity of 99.92%.
Medchemexpress LLC 4-hydroperoxycyclophosphamide | 39800-16-3 | MFCD01710226 | >98.0% | 293.08 g/mol | C7H15Cl2N2O4P | 50 MG
4-hydroperoxycyclophosphamide is the activated hydroperoxide metabolite of cyclophosphamide used as a research reagent to study DNA cross-linking, apoptosis, and reactive oxygen species (ROS)-mediated mitochondrial death pathways. It is supplied for research use only and not for human or clinical use.
- Activated metabolite that cross-links DNA and induces T cell apoptosis.
- Useful for in vitro studies of apoptosis, oxidative stress, and DNA damage.
- High solubility in DMSO (50 mg/mL); ultrasonic agitation recommended for dissolution.
- Storage guidance: store at -20°C under inert gas; in solution store at -80°C up to 6 months, or -20°C up to 1 month under nitrogen.
- Molecular weight 293.08 g/mol; formula C7H15Cl2N2O4P.
- For research use only; not intended for human or clinical applications.