Organic phosphoric acids and derivatives
Apexbio Technology LLC Sitagliptin (phosphate) 654671-78-0 100mg
Sitagliptin phosphate (CAS 654671-78-0) is a potent selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP4) DPP4 is a membrane-bound serine protease widely expressed on various cells involved in immune modulation signal transduction and apoptosis Sitagliptin competitively inhibits DPP4 activity exhibiting an IC50 value of approximately 18 nM with minimal cross-inhibition of structurally related proteases Clinically sitagliptin has shown efficacy in improving fasting and postprandial glycemic control and enhancing -cell function in type 2 diabetes research settings without increased cardiovascular risks
eMolecules 838-85-7 | Diphenyl phosphate | Combi-Blocks250.190 | C12H11O4P | 98.000 | OP(=O)(Oc1ccccc1)Oc1ccccc1 | 5g | 232305187
Diphenyl phosphate | Combi-Blocks | 838-85-7250.190 | C12H11O4P | 98.000 | OP(=O)(Oc1ccccc1)Oc1ccccc1 | 5g | 232305187
Medchemexpress LLC Pyridoxal phosphate | 54-47-7 | 99.95% | 500 UG
Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia. This product is for research use only.
- Severely inhibits DNA Polymerase and RNase H, leading to an immediate reduction in DNA synthesis.
- Conjugation to pyridoxal phosphate fully inhibits NEIL2.
- Activates the ERK/c-Jun signaling pathway and promotes IGFBP1 protein expression in HepG2 cells.
- Inhibits the proliferation of cancer cells SK-OV-3 and OVCAR-3.
- Alleviates Aβ25-35-induced spatial and long-term memory impairment in mouse models.
- Inhibits the formation of advanced glycation end-products (AGEs) and prevents the progression of diabetic nephropathy.
Medchemexpress LLC Dope-peg-mal | CAS | MFCD | 98.2% | 2000 (average) | 50 MG
DOPE-PEG-Mal (MW 2000) is a phospholipid-polyethylene glycol conjugate designed for preparing liposomes and nanoparticles and for thiol-specific bioconjugation. The maleimide functional group reacts with thiols at pH 6.5-7.5 to form stable thioether bonds. Supplied as a solid with high purity for research applications.
- Phospholipid-PEG conjugate suitable for liposome and nanoparticle formulation.
- Maleimide group reacts with thiols at pH 6.5-7.5.
- Average molecular weight 2000.
- Purity 98.2%.
- Soluble in DMSO (~100 mg/mL; may require ultrasonic treatment).
- Powder stable at -20 °C for extended storage.
- Intended for research use only.
AdipoGen 4-MU phosphate disodium salt
Chemical. CAS 22919-26-2. Formula C10H7Na2O6P. MW 300.11. 4-Methylumbelliferyl phosphate 4-MUP is a fluorogenic substrate for phosphatases mainly alkaline. It is converted to the fluorescent product 4-methylumbelliferone 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. Therefore, this phosphatase substrate is not well suited for living cell or continuous assays since 4-MU only develops maximum fluorescence at a pH value of >10. Spectral data lambdaex=319nm lambdaem=384nm pH 9.0. lambdaex=360nm lambdaem=449nm for reaction product.
eMolecules 2416138-42-4 | (S)-2-Amino-4-(bis(2-((3-methylbenzyl)oxy)benzyl)amino)butanoic acid hydrochloride | 50mg
ChemScene | 2-Mercapto-1H-benzo[d]imidazole-5-carboxylic acid | 1g | 536786506 | CS-0040792 | 58089-25-1 | MFCD01233170 | 194.210 | C8H6N2O2S
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Medchemexpress LLC Disodium hydrogen phosphate | 7558-79-4 | MFCD00003496 | 99.2% | 141.96 g/mol | Na2HPO4 | 5g
Disodium phosphate is commonly used as a food additive buffer and laboratory reagent Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers detergents and water treatment products Additionally it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions
Medchemexpress LLC Disodium hydrogen phosphate anhydrous | 7558-79-4 | MFCD00003496 | 99.0% | 141.96 g/mol | Na2HPO4 | 1g
Disodium phosphate is commonly used as a food additive buffer and laboratory reagent Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers detergents and water treatment products Additionally it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions
eMolecules 103-23-1 | Bis(2-ethylhexyl) adipate | Oakwood Chemicals | MFCD00009496 | 370.574 | C22H42O4 | 98.000 | CCCCC(CC)COC(=O)CCCCC(=O)OCC(CC)CCCC | 25g | 480168369
Bis(2-ethylhexyl) adipate | Oakwood Chemicals | 103-23-1 | MFCD00009496 | 370.574 | C22H42O4 | 98.000 | CCCCC(CC)COC(=O)CCCCC(=O)OCC(CC)CCCC | 25g | 480168369