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Filtered Search Results
Medchemexpress LLC Momelotinib sulfate | 1056636-06-6 | 99.9% | 610.62 | 1 ML
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Momelotinib sulfate is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 values of 11 nM and 18 nM, respectively. It exhibits 10-fold selectivity versus JAK3 (IC50=155 nM). It inhibits the growth of Ba/F3-JAK2V617F and human erythroleukemia (HEL) cells.
- Inhibits JAK1 and JAK2
- Shows selectivity over JAK3
- Inhibits the growth of certain leukemia cells
- Administered orally in preclinical studies
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Medchemexpress LLC Chondroitin sulfate methacryloyl | 99.5% | 10 MG
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Chondroitin sulfate methacryloyl (CSMA) is a methacrylated derivative of chondroitin sulfate developed for photocrosslinkable hydrogel formation and 3D bioprinting. It is biocompatible, forms fibrous hydrogels under photoinitiation, and the degree of methacrylation enables tuning of mechanical strength, swelling behavior, and enzymatic degradability. Supplied as a white to off-white powder; soluble in water (≈20 mg/mL with sonication). Store powder at -20 °C.
- Biocompatible methacrylated polysaccharide suitable for hydrogel scaffolds.
- Photocrosslinkable for rapid curing with appropriate photoinitiators.
- Degree of methacrylation tunable to adjust mechanics and degradation.
- Soluble in water with sonication for solution preparation.
- Stable as a powder at -20 °C for long-term storage.
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Aobchem AOBCHEM
5000996445 2 6-DIMETHYL-4-PROPOXYPHENYL
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TARGETMOL CHEMICALS INC VORAPAXAR SULFATE 10MG
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Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist. purity: 99%
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Medchemexpress LLC Iobenguane (sulfate) | 87862-25-7 | 25 MG
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Iobenguane sulfate is an analytical standard intended for research and analytical applications. This compound, an analogue of the neurotransmitter norepinephrine, exhibits antitumor activity. Radioiodinated iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical for the diagnosis and treatment of adrenergic tumors. It also serves as a high-affinity substrate for cholera toxin, interfering with cellular mono(ADP-ribosylation).
- Used as an analytical standard
- Intended for research and analytical applications
- Analog of norepinephrine with antitumor activity
- Radioiodinated form used as a tumor-targeted radiopharmaceutical
- High-affinity substrate for cholera toxin
- Commonly used in HPLC, GC, and MS experiments
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eMolecules 124939-70-4 | diethyl 8-bromooctylphosphonate | Broadpharm | MFCD24539460 | 329.215 | C12H26BrO3P | 96.000 | CCOP(=O)(CCCCCCCCBr)OCC | 1g | 210965599
diethyl 8-bromooctylphosphonate | Broadpharm | 124939-70-4 | MFCD24539460 | 329.215 | C12H26BrO3P | 96.000 | CCOP(=O)(CCCCCCCCBr)OCC | 1g | 210965599
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Medchemexpress LLC p-Cresyl sulfate potassium | 91978-69-7 | 99.9% | 226.29 | 50 MG
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p-Cresyl sulfate potassium (Standard) is an analytical standard used in research and analytical applications. It is a uremic toxin linked to renal damage and dysfunction. This compound exhibits antiproliferation activity, influences protein expression (HIF-1α, VHL, HIF-2α), and activates JNK and p38 MAPK signaling pathways. It is suitable for experiments involving HPLC, GC, and MS.
- Analytical standard for research.
- Uremic toxin causing renal damage and dysfunction.
- Exhibits antiproliferation activity.
- Modulates protein expression (HIF-1α, VHL, HIF-2α).
- Induces epithelial-mesenchymal transition (EMT).
- Activates JNK and p38 MAPK signaling pathways.
- Applicable in HPLC, GC, and MS research.
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GRAINGER INC SODIUM LIGNINSULFONATE 25G
502781205 SODIUM LIGNINSULFONATE 25G
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TARGETMOL CHEMICALS INC ISEPAMICIN SULFATE 50MG
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Also available in 5 mg 10 mg 25 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Isepamicin sulfate (sch21420) Sulphate) an aminoglycoside antibacterial with good activity against strains producing type I 6-acetyltransferase inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit. purity: 99%
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Medchemexpress LLC Vinblastine (sulfate) | 143-67-9 | 99.86% | 909.05 | 100 MG
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Vinblastine sulfate is a cytotoxic alkaloid that targets various cancer types by inhibiting microtubule formation and suppressing nAChR (IC50 8.9 μM). It blocks mitosis (IC50 0.8 nM in HeLa cells), leading to cell apoptosis. For storage, keep sealed at 4°C, away from moisture and light. In solvent, store at -80°C for 6 months or -20°C for 1 month, similarly sealed. Room temperature shipping is suitable for durations under 2 weeks.
- Inhibits microtubule formation.
- Suppresses nAChR with an IC50 of 8.9 μM.
- Blocks mitosis, leading to cell apoptosis.
- Induces apoptosis via Bax/Bcl-2 imbalance.
- Suppresses NFκB expression and depresses NFκB-DNA binding activity.
- Triggers apoptosis by causing a loss of mitochondrial membrane potential and activating caspases.
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Medchemexpress LLC Sodium octadecyl sulfate | 1120-04-3 | MFCD00007469 | 98.0% | 372.54 g/mol | C18H37NaO4S | 1 G
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Sodium octadecyl sulfate is an anionic surfactant and biochemical reagent supplied as a white to off-white solid for research use. It is commonly used as a surfactant and formulation component in biochemical assays, sample preparation, and in vivo formulations, and includes solubility and storage guidance for laboratory handling.
- High purity (98.0%).
- White to off-white solid physical form.
- Soluble in DMSO; warming and sonication improve dissolution.
- Formulatable for in vivo use in 10% DMSO/90% corn oil.
- Recommended storage: sealed at 4°C; stock solutions -80°C (6 months) or -20°C (1 month).
- Intended for research use only.
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Sigma Aldrich Fine Chemicals Biosciences beta-Acetyl-gamma-O-hexadecyl-L-alpha-phosphatidylcholine hydrate >=98% | 74389-68-7 (anhydrous) | MFCD00150679 | 5MG
beta-Acetyl-gamma-O-hexadecyl-L-alpha-phosphatidylcholine hydrate >=98% | Purity: >=98% | 74389-68-7 (anhydrous) | MFCD00150679 | 5MG
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Matrix Scientific N,N-DIMETHYLSULFAMIDEN,N-DIM-1
N,n-dimethylsulfamide Mf C2h8n2o2s Mw 124.16 Cas 3984-14-3 Mdl MFCD01861286
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AdipoGen Rhodamine B octadecyl est ClO4
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Chemical. CAS 142179-00-8. Formula C46H67ClN2O7. MW 795.49. Synthetic. Sensitive membrane dye used for potassium fiber-optic sensors and nitrate sensing and other investigations of membranes. Lipophilic energy transfer acceptor from lipophilic fluoresceins in fluorescence energy transfer FRET assays in cell fusion experiments Ex/Em 554/575nm in methanol.
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Medchemexpress LLC Atropine sulfate monohydrate | 5908-99-6 | MFCD00074815 | 99.9% | 1 ML
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Atropine sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist. It demonstrates high potency with IC50 values of 0.39 nM for Human mAChR M4 and 0.71 nM for Chicken mAChR M4. This compound is known to inhibit ACh-induced relaxations in human pulmonary veins.
- Competitive muscarinic acetylcholine receptor (mAChR) antagonist.
- Inhibits ACh-induced relaxations in human pulmonary veins.
- Suitable for research on anti-myopia.
- Suitable for research on bradycardia.
- Available as a solid, white to off-white appearance.
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