Organic sulfuric acids and derivatives
Medchemexpress LLC FITC-dextran sulfate | 10 MG
FITC-dextran sulfate (MW 500 kDa) is a high-molecular-weight, anionic polysaccharide covalently labeled with fluorescein isothiocyanate (FITC). It is used as a fluorescent tracer and permeability probe in biological and fluorescence-based assays where a large, anionic, fluorescent marker is required. Handle and store protected from light at low temperatures for best stability.
- Fluorescently labeled with FITC for robust fluorescence signal.
- High average molecular weight (~500 kDa) for restricted diffusion and barrier permeability studies.
- Anionic dextran sulfate backbone for charge-based interactions.
- Store protected from light at low temperatures to preserve stability.
- Offered in small-scale quantities suitable for laboratory experiments.
Medchemexpress LLC Selumetinib sulfate | 943332-08-9 | 99.58% | C17H17BrClFN4O7S | 1 G
Selumetinib sulfate is a selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. It inhibits ERK1/2 phosphorylation and can penetrate the blood-brain barrier (BBB).
- Causes a time- and dose-dependent reduction in DNA synthesis and cell viability
- Induces growth arrest and apoptosis associated with the inactivation of ERK in primary cells
- Shows anti-proliferative effects through G0/G1 arrest
- Results in growth inhibition of cell lines containing B-Raf and Ras mutations
- Decreases the growth rate of xenografts in a dose-dependent manner
- Suppresses the growth of xenografts
- Inhibits ERK1/2 phosphorylation and growth of xenograft tumors in nude mice
- Tumor regressions observed in xenograft models
Medchemexpress LLC Chondroitin sulfate sodium (from bovine) | 9007-28-7 | 99.4% | 1 G
Chondroitin sulfate from Bovine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is for research use only and not sold to patients.
- Biochemical reagent for life science research
- Not sold to patients
Medchemexpress LLC Sodium laureth sulfate | 9004-82-4 | 70% | (C2H4O)nC12H26O4S.Na | 25 G
Sodium laureth sulfate (70% in water) is an anionic active agent that exhibits excellent decontamination, emulsification, dispersion, wetting, and antifungal properties. It is intended for research use only.
- Anionic active agent
- Exhibits decontamination properties
- Exhibits emulsification properties
- Exhibits dispersion properties
- Exhibits wetting properties
- Provides antifungal properties
- Enhances inactivation efficiency against *S. cerevisiae* cells
- Disrupts membrane integrity in *S. cerevisiae* cells
- Increases cell membrane permeability in *S. cerevisiae* cells
- Elevates lysosomal enzyme activities in guinea pigs
Medchemexpress LLC Sisomicin sulfate (Standard) | 53179-09-2 | 99.3% | 50 MG
Sisomicin (sulfate) (Standard) serves as the analytical standard for Sisomicin (sulfate) and is designated for research and analytical applications. This broad-spectrum aminoglycoside antibiotic is derived from *Micromonospora inyoensis* and exhibits high activity against Gram-positive bacteria.
- The compound is an analytical standard, serving as the reference standard for assays.
- It is frequently utilized in qualitative, quantitative, and methodological research experiments involving HPLC, GC, and MS.
Medchemexpress LLC Sisomicin sulfate | 53179-09-2 | 99.3% | 100 MG
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. It exhibits high activity against Gram-positive bacteria. Sisomicin sulfate (6.25 μg/mL) completely inhibits the growth of various clinical isolates of bacteria, such as Klebsiella, Salmonella, Citrobacter, and Staphylococcus aureus. Sisomicin sulfate (20 μg/mL; 30 min) has insignificant impairment on polymorphonuclear neutrophil (PMN). In vivo, Sisomicin sulfate (4 mg/kg; ip; single dose) appears to accumulate and persist in the kidneys, showing potential renal toxicity in rats.
- Broad-spectrum aminoglycoside antibiotic
- Produced by Micromonospora inyoensis
- Highly active against Gram-positive bacteria
- Inhibits the growth of various clinical isolates of bacteria, including Klebsiella, Salmonella, Citrobacter, and Staphylococcus aureus
Medchemexpress LLC Imazalil (sulfate) | 58594-72-2 | 99.6% | 1 G
Imazalil (Enilconazole) sulfate is a fungicide with oral activity. It strongly activates mPXR but not mCAR in mouse liver. It is commonly used to protect various agricultural crops against fungal attack. Imazalil sulfate is known to induce developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder. It is for research use only and not sold to patients.
- Fungicide
- Oral activity
- Strongly activates mPXR in mouse liver
- Commonly used to protect agricultural crops against fungal attack
- Induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder
Medchemexpress LLC BM 15766 sulfate | 86621-94-5 | 98.2% | 482.98 | 25 MG
BM 15766 sulfate is an inhibitor of 7-dehydrocholesterol δ7-reductase, which works to reduce plasma cholesterol levels. It functions as a hypolipidemic agent.
- Inhibitor of 7-dehydrocholesterol δ7-reductase
- Reduces plasma cholesterol levels
- Acts as a hypolipidemic agent
- Inhibits 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in HL60 cells with an IC50 of 500 nM
TARGETMOL CHEMICALS INC EFEGATRAN SULFATE 5MG
Also available in 50 mg 100 mg and bulk. Please contact Fisher for quotes. Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders. purity: 98%