Organic sulfuric acids and derivatives
Apexbio Technology LLC Phenyl sulfate 937-34-8 25mg
Phenyl sulfate (CAS 937-34-8) is a protein-bound uremic solute implicated in oxidative stress-related cellular injury It accumulates in patients with chronic kidney disease (CKD) inducing reactive oxygen species generation and diminishing intracellular glutathione levels Studies using porcine renal tubular cells demonstrated that phenyl sulfate enhances vulnerability to oxidative damage significantly amplifying hydrogen peroxide-induced cytotoxicity In murine models with diabetic kidney disease (KKAy mice on high-fat diets) phenyl sulfate administration intensified albuminuria and structural renal damage including podocyte effacement and basement membrane alterations Consequently phenyl sulfate serves as a biomarker in CKD research useful in assessing interventions targeting protein-bound uremic toxins
Medchemexpress LLC Phenyl sulfate | 937-34-8 | 98% | 50 MG
Phenyl sulfate (Standard) is an orally active gut microbiota-derived metabolite, primarily used as an analytical standard for research and analytical applications. It has been identified as a disease marker in diabetic kidney disease, capable of inducing albuminuria and podocyte damage in experimental diabetes models. This analytical standard is suitable for use in qualitative, quantitative, and methodological research experiments, including techniques like HPLC, GC, and MS.
- Used as an analytical standard for research
- Suitable for HPLC, GC, and MS applications
- Functions as an orally active gut microbiota-derived metabolite
- Identified as a disease marker in diabetic kidney disease
Medchemexpress LLC Phenyl sulfate | 937-34-8 | 99.5% | 25 MG
Phenyl sulfate is an orally active gut microbiota-derived metabolite. It induces albuminuria and podocyte damage in experimental models of diabetes and can be used as a disease marker in diabetic kidney disease.
- Orally active gut microbiota-derived metabolite
- Induces albuminuria and podocyte damage in experimental models
- Used as a disease marker in diabetic kidney disease
Medchemexpress LLC Phenyl hydrogen sulfate | 937-34-8 | 99.5% | 100 MG
Phenyl sulfate is an orally active, gut microbiota-derived metabolite. It induces albuminuria and podocyte damage in experimental models of diabetes and can be used as a disease marker in diabetic kidney disease. It appears as a white to off-white solid.
- Orally active gut microbiota-derived metabolite
- Induces albuminuria and podocyte damage in experimental models of diabetes
- Used as a disease marker in diabetic kidney disease
- Appears as a white to off-white solid
- High purity of 99.47%
- Soluble in water
Medchemexpress LLC Phenyl hydrogen sulfate | 937-34-8 | MFCD00059840 | 99.6% | 174.17 | C6H6O4S | 5 MG
Phenyl sulfate is an analytical standard and a gut microbiota-derived metabolite used in biochemical and metabolic research. It is associated with albuminuria and podocyte damage in experimental models and is used as a marker in studies of diabetic kidney disease.
- Analytical standard for biochemical and metabolic studies.
- Molecular formula: C6H6O4S.
- Molecular weight: 174.17 g/mol.
- High purity (~99.6%) suitable for analytical applications.
- Available as solid (1, 5, 10, 25, 50, 100 mg) and solution (10 mM, 1 mL).
- Physical state: solid; also supplied as aqueous solution.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Used as a marker in renal disease and diabetic kidney disease research.