Vinylogous acids
eMolecules 90322-37-5 | 2-Oxoindoline-4-carboxylic acid | ChemScene | MFCD10000702 | 177.159 | C9H7NO3 | 96.000 | OC(=O)c1cccc2NC(=O)Cc12 | 250mg | 536848463
2-Oxoindoline-4-carboxylic acid | ChemScene | 90322-37-5 | MFCD10000702 | 177.159 | C9H7NO3 | 96.000 | OC(=O)c1cccc2NC(=O)Cc12 | 250mg | 536848463
Medchemexpress LLC IACS-8803 disodium | 2243079-36-7 | C20H21FN10Na2O9P2S2 | 10MG
IACS-8803 disodium is a cyclic dinucleotide stimulator of interferon genes (STING) agonist described by investigators at the Institute for Applied Cancer Science (MD Anderson). Supplied as the disodium salt for research use, it shows robust systemic antitumor efficacy in preclinical studies and includes documented solubility and formulation guidance for in vitro and in vivo experiments.
- Potent activation of the STING pathway demonstrated in preclinical studies.
- Water-soluble disodium salt with documented solubility in DMSO, water, and PBS.
- Suggested in vivo formulations and dosing vehicles provided for clear solution preparation.
- High chemical purity suitable for laboratory research applications.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC IACS-8803 disodium | 2243079-36-7 | 98.8% | 736.50 g·mol⁻¹ | C20H21FN10Na2O9P2S2 | 5 MG
IACS-8803 disodium is a potent cyclic dinucleotide STING agonist provided as the disodium salt for preclinical research. It activates STING signaling to stimulate interferon responses and has demonstrated robust systemic antitumor efficacy in mouse models. The compound is a white to off-white solid with high reported purity and is supplied in small solid quantities or as a DMSO solution.
- Activates STING pathway in vitro and in vivo.
- Demonstrates robust systemic antitumor efficacy in preclinical models.
- High purity suitable for research applications.
- Soluble in DMSO and moderately soluble in water; vehicle protocols available for in vivo use.
- Store under nitrogen, away from moisture; follow cold storage recommendations.
- Available in small-mass solid quantities and as a prepared solution for convenience.
Sigma Aldrich Fine Chemicals Biosciences 4-Hydroxy-2,5-dimethyl-3(2H)-furanone | 3658-77-3 | MFCD00010706 | Sample
4-Hydroxy-2,5-dimethyl-3(2H)-furanone | Purity: ≥98% | Mol Wt: 128.13 | 3658-77-3 | MFCD00010706 | Sample
eMolecules 60-80-0 | Antipyrine | Oakwood Chemicals | MFCD00003146 | 188.230 | C11H12N2O | 98.000 | Cc1cc(=O)n(-c2ccccc2)n1C | 25g | 480166984
Antipyrine | Oakwood Chemicals | 60-80-0 | MFCD00003146 | 188.230 | C11H12N2O | 98.000 | Cc1cc(=O)n(-c2ccccc2)n1C | 25g | 480166984
Accela Chembio Inc 6-bromo-4-hydroxyquinazoline | 25g | 32084-59-6 | MFCD00115131 | 97+% | Shelf Life: 2160 Days | Light Sensitive
6-bromo-4-hydroxyquinazoline | 25g | 32084-59-6 | MFCD00115131 | 97+% | Shelf Life: 2160 Days | Light Sensitive
eMolecules 313535-84-1 | Methyl 4-hydroxyquinazoline-7-carboxylate | Oakwood Chemical | MFCD00681283 | 204.185 | C10H8N2O3 | 95.000 | COC(=O)c1ccc2c(O)ncnc2c1 | 1g | 537717229
Methyl 4-hydroxyquinazoline-7-carboxylate | Oakwood Chemical | 313535-84-1 | MFCD00681283 | 204.185 | C10H8N2O3 | 95.000 | COC(=O)c1ccc2c(O)ncnc2c1 | 1g | 537717229
Medchemexpress LLC VU0810464 | 2126040-21-7 | 99.3% | 50 MG
VU0810464 is a potent and selective non-urea G protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. It demonstrates nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels. It exhibits improved brain penetration and reduces stress-induced hyperthermia (SIH) in mice by activating Kir3 channels.
- Potent and selective activator of GIRK (Kir3) channels
- Displays nanomolar potency for neuronal and GIRK1/4 channels
- Exhibits improved brain penetration
- Reduces stress-induced hyperthermia (SIH) in mice
![Accela Chembio Inc 4-hydroxythieno[3 | 2-d]pyrimidine | 5g | 16234-10-9 | MFCD11040452 | 97+% | Shelf Life: 1260 Days | Light Sensitive](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00116475-SY006112-5G.PNG-250.jpg)
Accela Chembio Inc 4-hydroxythieno[3 | 2-d]pyrimidine | 5g | 16234-10-9 | MFCD11040452 | 97+% | Shelf Life: 1260 Days | Light Sensitive
4-hydroxythieno[3 | 2-d]pyrimidine | 5g | 16234-10-9 | MFCD11040452 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Sigma Aldrich Fine Chemicals Biosciences 2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | 4077-47-8 | MFCD00209504 | 1KG
2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | Purity: >=98% | Mol Wt: 142.15 | 4077-47-8 | MFCD00209504 | 1KG
Sigma Aldrich Fine Chemicals Biosciences 2,5-Dimethyl-4-methoxy-3(2H)-furanone >=97%, FG | 4077-47-8 | MFCD00209504 |
2,5-Dimethyl-4-methoxy-3(2H)-furanone >=97%, FG | Purity: >=97% | Mol Wt: 142.15 | 4077-47-8 | MFCD00209504 |
Sigma Aldrich Fine Chemicals Biosciences 2,5-Dimethyl-4-methoxy-3(2H)-furanone >=97%, FG | 4077-47-8 | MFCD00209504 | 1KG
2,5-Dimethyl-4-methoxy-3(2H)-furanone >=97%, FG | Purity: >=97% | Mol Wt: 142.15 | 4077-47-8 | MFCD00209504 | 1KG
Sigma Aldrich Fine Chemicals Biosciences 2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | 4077-47-8 | MFCD00209504 | 100G
2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | Purity: >=98% | Mol Wt: 142.15 | 4077-47-8 | MFCD00209504 | 100G
Accela Chembio Inc Hypoxanthine | 100g | 68-94-0 | MFCD00005725 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Hypoxanthine | 100g | 68-94-0 | MFCD00005725 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Medchemexpress LLC Revumenib | 2169919-21-3 | 99.99% | 630.82 | 50 MG
Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding Ki of 0.149 nM and a cell-based IC50 of 10-20 nM. It can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).
- Potent and specific Menin-MLL inhibitor
- Applicable for research into MLL-rearranged acute leukemias (ALL and AML)
- Shows in vivo plasma IC50 of 53 nM
- Provides significant survival benefit and leukemic control in aggressive MOLM-13 disseminated xenografts in vivo