Azetidines
Medchemexpress LLC Clavulanate lithium | 61177-44-4 | 99.9% | C8H8LiNO5 | 5 MG
Clavulanate lithium is a potent beta-lactamase inhibitor that also acts as an antibiotic. While exhibiting weak antibacterial activity alone, it prevents the inactivation of beta-lactam antibiotics by microbial lactamase when combined with them. It has a molecular weight of 205.09 and an appearance of a solid, white to off-white color.
- Potent beta-lactamase inhibitor
- Acts as an antibiotic
- Prevents inactivation of beta-lactam antibiotics
- Solid, white to off-white appearance
- Soluble in H2O and DMSO
Medchemexpress LLC NSC319726 (ZMC1) | 71555-25-4 | 99.6% | 234.32 | 100 MG
NSC319726 (ZMC1) is a mutant p53R175 reactivator. It inhibits the growth of fibroblasts expressing the p53R175 mutation with an IC50 of 8 nM, showing no inhibition for p53 wild-type cells. This compound has demonstrated significant inhibition of tumor growth in TOV112D (p53R175H) xenografts in vivo, providing evidence for allele-specific p53 mutant reactivation.
- Mutant p53R175 reactivator with IC50 of 8 nM against p53R175 mutation
- No inhibition for p53 wild-type cells
- High sensitivity for MEF-p53R172H/R172H cell line
- Inhibits tumor growth in TOV112D (p53R175H) xenografts in vivo
- Provides in vivo evidence for allele-specific p53 mutant reactivation
- CC50 < 0.02 μM for Caco-2 cell toxicity
- IC50 < 0.02 μM for Caco-2 cell SARS-CoV-2 cytotoxicity inhibition
- EC50 0.005 μM for TOV112D cell growth inhibition
![eMolecules ChemScene / (R)-Azetidine-2-carbonitrileoxalate / 100mg / 714104305 / CS-0172824 / 0.000 / 2173052-89-4 / [null] / 172.140 / C6H8N2O4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502463335.JPG-250.jpg)
eMolecules ChemScene / (R)-Azetidine-2-carbonitrileoxalate / 100mg / 714104305 / CS-0172824 / 0.000 / 2173052-89-4 / [null] / 172.140 / C6H8N2O4
ChemScene / (R)-Azetidine-2-carbonitrileoxalate / 100mg / 714104305 / CS-0172824 / 0.000 / 2173052-89-4 / [null] / 172.140 / C6H8N2O4
Medchemexpress LLC Selpercatinib 25mg | 2152628-33-4 | 25 MG
Selpercatinib analytical standard for research and analytical applications. It is intended as a reference standard for qualitative and quantitative assays, including HPLC, GC, and MS. CAS 2152628-33-4; molecular formula C29H31N7O3; molecular weight 525.60 g·mol^-1.
- Analytical standard suitable for HPLC, GC, and MS
- Potent, selective RET kinase inhibitor used in research
- Available in multiple pack sizes, including 25 MG
- Intended for qualitative and quantitative reference assays
Medchemexpress LLC Azetidine-2-carboxylic acid | 2517-04-6 | 98.0% | C4H7NO2 | 5 G
Azetidine-2-carboxylic acid is a non-proteinogenic amino acid homologue of proline. It is found in common beets and can be misincorporated into proteins in place of proline in many species, including humans. It is described as a toxic and teratogenic agent.
- Non-proteinogenic amino acid homologue of proline
- Found in common beets
- Can be misincorporated into proteins
- Toxic and teratogenic agent
- Incorporated into collagen synthesized by chick embryo cartilage in vitro
Selleck Chemical LLC Azetidine-2-carboxylic acid
Azetidine-2-carboxylic acid (L-Aze) is a toxic and teratogenic non-protein amino acid that is misincorporated into protein in place of proline altering collagen keratin hemoglobin and protein folding
Medchemexpress LLC 1-Boc-L-azetidine-2-carboxylic acid | 51077-14-6 | 201.22 | 1 G
(S)-1-(tert-Butoxycarbonyl)azetidine-2-carboxylic acid is a biochemical reagent. It can be utilized as a biological material or organic compound for life science related research.
- Can be used as a biological material
- Can be used as an organic compound
- Suitable for life science related research