Azolines
eMolecules 6-Hydroxy-2-mercaptobenzimidazole | 92806-98-9 | MFCD26131865 | 1g
WuXi ChemSupply | 6-Hydroxy-2-mercaptobenzimidazole | 1g | 599167443 | LN01286296 | 95.000 | 92806-98-9 | MFCD26131865 | 166.200 | C7H6N2OS
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Medchemexpress LLC 5-nitrobenzimidazole | 94-52-0 | 99.7% | 163.14 | 25 G
5-nitrobenzimidazole is a genotoxic nitro compound and a 6-aminopurine analogue. It exhibits a slight inhibitory effect on xanthine oxidase, making it suitable for research related to hyperuricemia.
- Genotoxic nitro compound
- 6-aminopurine analogue
- Slight inhibitory effect on xanthine oxidase
- Suitable for hyperuricemia research
![Medchemexpress LLC Benzo[k]fluoranthene | 207-08-9 | 252.31 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000400457-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzo[k]fluoranthene | 207-08-9 | 252.31 | 1 MG
Benzo[k]fluoranthene is a polycyclic aromatic hydrocarbon (PAH) that possesses carcinogenic and genotoxic properties.
- Product type: Polycyclic aromatic hydrocarbon (PAH).
- Biological activity: Carcinogenic and genotoxic.
- Usage: For research use only; not sold to patients.
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage: Solution, -20°C, protected from light, with a shelf life of 2 years.
eMolecules Oakwood Chemicals 2-Methyl-2-propanethiol 25g 480148923 098849 75-66-1 MFCD00004857 90.180 C4H10S
Oakwood Chemicals 2-Methyl-2-propanethiol 25g 480148923 098849 75-66-1 MFCD00004857 90.180 C4H10S
Apexbio Technology LLC Methimazole 60-56-0 10g
Methimazole is a small-molecule inhibitor targeting intercellular adhesion molecule-1 (ICAM-1) gene transcription It is designed to modulate ICAM-1 expression thereby regulating cell adhesion processes mediated by immunoglobulin superfamily members and integrins such as LFA-1 and Mac-1 Methimazole exerts its biological activity primarily through modulation of signal transducer and activator of transcription 1 (STAT1) In cell-based studies using thyroid cell models methimazole demonstrates inhibitory activity suppressing ICAM-1 mRNA expression induced by interferon-gamma (IFN- ) and H O Based on these pharmacological properties methimazole holds research potential in studying autoimmune thyroid conditions and as an agent to induce hypothyroidism in animal models for thyroid dysfunction research
Medchemexpress LLC 2-(2′-Pyridyl)benzimidazole | 1137-68-4 | 99.88% | 195.22 | 50 G
2-(2′-Pyridyl)benzimidazole is a potentially tridentate ligand that can form stable complexes with various transition metal ions. It can be used as an anti-inflammatory agent and an inhibitor of *Escherichia coli* methionine aminopeptidase.
- Potentially tridentate ligand that can form stable complexes with various transition metal ions.
- Can be used as an anti-inflammatory agent.
- Can be used as an inhibitor of *Escherichia coli* methionine aminopeptidase.
Medchemexpress LLC 2-amino-5-mercapto-1,3,4-thiadiazole | 2349-67-9 | 99.9% | 133.20 | 1 KG
2-Amino-5-mercapto-1,3,4-thiadiazole is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. It is intended for research use only and not sold to patients.
- Biochemical reagent
- Can be used as a biological material
- Can be used as an organic compound for life science related research
Medchemexpress LLC m-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | 250 MG
m-PEG-thiol (MW 2000) is a PEG-based PROTAC linker for the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrade target proteins
Medchemexpress LLC m-PEG-thiol (MW 20000) | 95.0% | 50 MG
m-PEG-thiol (MW 20000) is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs operate by connecting two different ligands, one for an E3 ubiquitin ligase and another for a target protein, to exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins. This product is for research use only and has not been validated for medical applications.
- PEG-based PROTAC linker
- Designed for PROTAC synthesis
- Facilitates selective degradation of target proteins
- Average molecular weight of 20000
- Appears as a white to off-white solid
- Purity of 95.0%
Medchemexpress LLC Thiol-PEG-CH2COOH (MW 5000) | 95.0% | SMILES: SCCOCC(O)=O.[MW 5000].[n] | 50 MG
Thiol-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are composed of two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other targeting the protein intended for degradation, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Leverages the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Medchemexpress LLC Thiol-PEG-CH2COOH (MW 2000) | 95.0% | 100 MG
Thiol-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC m-PEG-thiol (MW 5000) | 88778-21-6 | 99.9% | 1 G
m-PEG-thiol (MW 5000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This product functions by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
- Purity 99.9%
- Molecular weight 5000 (Average)