Azolines
Medchemexpress LLC Thiol-PEG-CH2COOH (MW 2000) | 95.0% | 25 MG
Thiol-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC Thiol-PEG-CH2COOH | 95.0% | HS-(CH2-CH2-O)n-CH2COOH | 25 MG
Thiol-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. PROTACs utilize two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, to exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Target proteins selectively degraded
- Average molecular weight of 5000
- Purity of 95.0% by NMR
- Appearance is white to off-white solid
Medchemexpress LLC 3-Mercapto-1,2,4-triazole | 3179-31-5 | 98.0% | 101.13 | 250 G
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent suitable for life science related research. It serves as a biological material or organic compound, intended for research use only and not for patient applications.
- Utilized in a study to design a surface enhanced Raman scattering based probe for fast and accurate detection of DNA markers.
Medchemexpress LLC 4,7,10,13-Tetraoxapentadecanoic acid, 15-mercapto-, 1,1-dimethylethyl ester | 564476-33-1 | 97.0% | C15H30O6S | 250 MG
Thiol-PEG4-Boc is a PEG-based PROTAC linker, appearing as a colorless to light yellow liquid. It is suitable for the synthesis of PROTACs and complies with given specifications.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Colorless to light yellow liquid appearance
- Complies with specifications
- Target: PROTAC linkers
Aobchem 2 4 5-Tribromo-1-butyl-1H-imidazole | 97% | CAS 2302-24-1 | C7H9Br3N2 | 500mg
2 4 5-Tribromo-1-butyl-1H-imidazole | 97% | CAS 2302-24-1 | C7H9Br3N2 | 500mg
Aobchem 2-Methyl-3-(methylthio)benzo[b]thiophene | 95% | CAS 2918881-47-5 | C10H10S2 | 500mg
2-Methyl-3-(methylthio)benzo[b]thiophene | 95% | CAS 2918881-47-5 | C10H10S2 | 500mg
eMolecules 850589-33-2 | 4-(Thiazoline-3-carbonyl)phenylboronic acid | MFCD04115680 | 1g
Combi-Blocks | 4-(Thiazoline-3-carbonyl)phenylboronic acid | 1g | 117522295 | BB-3027 | 98.000 | 850589-33-2 | MFCD04115680 | 237.080 | C10H12BNO3S
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Selleck Chemical LLC MPP+ iodide-5mg
MPP+ iodide (N-Methyl-4-Phenylpyridinium Iodide), the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces autophagic cell death in SH-SY5Y cells. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons.
Sigma Aldrich Fine Chemicals Biosciences 2,6-Bis[(4S)-4-phenyl-2-oxazolinyl]pyridine 98% | 174500-20-0 | MFCD01863586 | 2G
2,6-Bis[(4S)-4-phenyl-2-oxazolinyl]pyridine 98% | Purity: 98% | Mol Wt: 369.42 | 174500-20-0 | MFCD01863586 | 2G
Aobchem Benzo[b]thien-2-yl(4-fluorophenyl)methanone | 95% | CAS 1306080-42-1 | C15H9FOS | 5g
Benzo[b]thien-2-yl(4-fluorophenyl)methanone | 95% | CAS 1306080-42-1 | C15H9FOS | 5g