Azolines
Cayman Chemical MethImazole 100mg
An inhibitor of thyroid hormone synthesis; a substrate of thyroid peroxidase; traps oxidized iodide and prevents its use by thyroglobulin; inhibits absorption of radiolabeled iodide by the thyroid gland in rats at 0.4 mg/kg; reduces the incidence of lymphocytic thyroiditis in the insulin-dependent type 1 diabetic BB/W rat; has been used to induce hypothyroidism in mice
Apexbio Technology LLC Methimazole 60-56-0 10g
Methimazole is a small-molecule inhibitor targeting intercellular adhesion molecule-1 (ICAM-1) gene transcription It is designed to modulate ICAM-1 expression thereby regulating cell adhesion processes mediated by immunoglobulin superfamily members and integrins such as LFA-1 and Mac-1 Methimazole exerts its biological activity primarily through modulation of signal transducer and activator of transcription 1 (STAT1) In cell-based studies using thyroid cell models methimazole demonstrates inhibitory activity suppressing ICAM-1 mRNA expression induced by interferon-gamma (IFN- ) and H O Based on these pharmacological properties methimazole holds research potential in studying autoimmune thyroid conditions and as an agent to induce hypothyroidism in animal models for thyroid dysfunction research
Medchemexpress LLC Propanoic acid, 3-(2-mercaptoethoxy)- | 1260092-48-5 | 95.0% | 150.20 | C5H10O3S | 10 MG
Thiol-PEG1-acid is a short polyethylene glycol (PEG) linker bearing a thiol (-SH) and a terminal carboxyl (-COOH). It is used as a bifunctional coupling reagent in bioconjugation and small-scale synthesis where selective thiol reactivity and carboxyl-mediated coupling are required.
- Short PEG linker with terminal thiol and carboxyl functional groups.
- Enables selective coupling via thiol chemistry, such as maleimide conjugation.
- Carboxyl group suitable for amide or ester bond formation with amines or alcohols.
- Low molecular weight (approx. 150.2 g/mol) for minimal steric hindrance.
- Typically supplied at 95.0% purity for research applications.
- Useful for bioconjugation, linker construction, and small-molecule linker design.
BOSTON FLUID SYSTEMS INC OG, 1G 0.172 IN. 4.4 MM
OG, 1G (0.172 in. [4.4 mm] ori fice) Series Stainle
Medchemexpress LLC Creatinine (Standard) | 60-27-5 | 99.99% | 50 MG
Creatinine (Standard) is an analytical standard intended for research and analytical applications. As a breakdown product of creatine phosphate in muscles, it serves as a reference standard for various assays.
- Analytical standard of creatinine
- Commonly used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Apexbio Technology LLC Irbesartan 138402-11-6 5mg
Irbesartan (CAS 138402-11-6) is a small molecule antagonist of the angiotensin II type 1 (AT1) receptor By selectively blocking AT1 receptor activity irbesartan inhibits angiotensin II-induced vasoconstriction thereby promoting vasodilation and reducing blood pressure In biomedical research irbesartan serves as an important pharmacological tool to investigate cardiovascular regulation hypertension pathogenesis and related signaling pathways Additionally its use extends to studies exploring therapeutic strategies for cardiovascular disorders
Apexbio Technology LLC Serotonin HCl(Synonyms: Serotonin hydrochloride, 5-Hydroxytryptamine hydrochloride, 5-HT hydrochloride), 50mg, CAS: 153-98-0.
Serotonin hydrochloride (CAS 153-98-0) is a monoamine neurotransmitter naturally derived from tryptophan that functions as an endogenous agonist of serotonin (5-HT) receptors Additionally serotonin hydrochloride acts as a non-competitive inhibitor of the enzyme catechol O-methyltransferase (COMT) exhibiting a binding affinity (Ki) of approximately 44 M Serotonin modulates diverse physiological processes including mood regulation sleep appetite sexual function and gastrointestinal activity Due to its role in mediating neurological and inflammatory pathways serotonin hydrochloride is widely utilized in research studies investigating depression anxiety disorders migraine pathophysiology and inflammation-associated hypersensitivity
Medchemexpress LLC Serotonin Transporter Antibody (YA1638) | 100 UL
Serotonin Transporter Antibody (YA1638) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting Serotonin Transporter. It is developed for research use, not for patient use. This antibody is supplied in PBS containing 50% glycerol, 0.5% BSA, and 0.02% sodium azide, and is shipped with blue ice. It is stored at -20°C for 1 year; avoid repeated freeze/thaw cycles.
- Rabbit-derived, monoclonal IgG antibody.
- Targets serotonin transporter.
- Reacts with human, mouse, and rat samples.
- Application: WB (Western Blot) with 1:500-1:1000 dilution.
- Purity achieved via affinity chromatography.
- Predicted and observed molecular weight: 70 kDa.
- Endogenous sensitivity.
Medchemexpress LLC Irbesartan | 138402-11-6 | MFCD00864464 | 99.95% | 50 MG
Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). It works by relaxing blood vessels, which helps to lower blood pressure and increase the supply of blood and oxygen to the heart. This compound is used in research for conditions such as high blood pressure, heart failure, and diabetic kidney disease.
- Orally active Ang II type 1 (AT1) receptor blocker (ARB)
- Relaxes blood vessels
- Lowers blood pressure
- Increases blood and oxygen supply to the heart
- Used for research in high blood pressure, heart failure, and diabetic kidney disease
Biotium Antibody Labeling Kits Antibody and Protein Labeling Kits Mix n Stain Antibody Labeling Kits CF488 1/EA
Mix-n-Stain CF Dye Nanobody Thiol Labeling Kits are optimized for labeling nanobodies with bright and photostable CF dyes in 2 hours with no purification Kits tolerate common stabilizers Green fluorescent CF488A has Ex/Em at 490/515 nm One labeling of 5-20 ug Nanobody Thiol per kit
Biotium Antibody Labeling Kits Antibody and Protein Labeling Kits Mix n Stain Antibody Labeling Kits CF583 1/EA
Mix-n-Stain CF Dye Nanobody Thiol Labeling Kits are optimized for labeling nanobodies with bright and photostable CF dyes in 2 hours with no purification Kits tolerate common stabilizers Red fluorescent CF583R has Ex/Em at 585/609 nm One labeling of 20-50 ug Nanobody Thiol per kit