Azolines
Medchemexpress LLC 5-Nitrobenzimidazole | 94-52-0 | 99.7% | 163.14 | 100 G
5-nitrobenzimidazole is a genotoxic nitro compound and a 6-aminopurine analogue. It exhibits a slight inhibitory effect on xanthine oxidase, with an IC50 of 86.84 μM. This compound can be utilized in hyperuricemia research.
- Genotoxic nitro compound
- 6-aminopurine analogue
- Slight inhibitory effect on xanthine oxidase
- IC50: 86.84 μM (xanthine oxidase)
- Can be used in research of hyperuricemia
- Appearance: Solid
- Color: White to yellow
Medchemexpress LLC M-peg-thiol (mw 550) | 134874-49-0 | MFCD21363241 | 99.0% | 550 (average) | (C2H4O)nC3H8OS | 1 G
m-PEG-thiol (average molecular weight 550) is a methoxy-terminated polyethylene glycol with a terminal thiol (mPEG-SH) used to introduce PEGylation and thiolation onto biomolecules and nanoparticle surfaces. It is commonly employed to modify DNA for loading onto gold nanorods and to provide a reactive thiol for surface conjugation.
- Provides a terminal thiol for covalent surface conjugation.
- Imparts steric stabilization and improved solubility to modified molecules.
- Average molecular weight of 550 for short PEG linker applications.
- High purity suitable for biochemical and nanomaterials research.
- Available in multiple pack sizes for flexible experimental use.
Medchemexpress LLC Thiol-PEG3-acid | 1347750-82-6 | ≥95.0% | 238.30 | 250 MG
Thiol-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and one for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
- Purity of ≥95.0%
- Molecular weight of 238.30
- CAS number 1347750-82-6
Medchemexpress LLC VH 101, thiol | 2358775-81-0 | 98.7% | C25H31FN4O4S2 | 250 MG
VH 101, thiol is a VHL ligand for the synthesis of PROTACs, suitable for research applications.
- VHL ligand for PROTAC synthesis.
- Appears as a solid.
- Molecular weight of 534.67.
Medchemexpress LLC 2-(2'-Pyridyl)benzimidazole | 1137-68-4 | 99.9% | 195.22 | 5 G
2-(2'-Pyridyl)benzimidazole is a potentially tridentate ligand capable of forming stable complexes with various transition metal ions. It can also function as an anti-inflammatory agent and an inhibitor of *Escherichia coli* methionine aminopeptidase.
- Potentially tridentate ligand
- Forms stable complexes with various transition metal ions
- Can be used as an anti-inflammatory agent
- Functions as an inhibitor of *Escherichia coli* methionine aminopeptidase
Medchemexpress LLC Thiol-PEG-acetic acid (SH-PEG-COOH) | 00-00-0 | 95.0% | HSC2H4O(C2H4O)nCH2CO2H | 10MG
Thiol-PEG-CH2COOH (MW 5000) is a heterobifunctional polyethylene glycol linker bearing a thiol at one terminus and a carboxylic acid at the other. It provides a flexible spacer for PROTAC assembly and other bioconjugation workflows, enabling orthogonal attachment strategies while maintaining solubility and spacer length control.
Medchemexpress LLC 3H-1,2,4-Triazole-3-thione, 1,2-dihydro- | 3179-31-5 | 99.78% | 101.13 | 25 G
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent used in life science related research. It was also utilized in a study to design a surface-enhanced Raman scattering-based probe for fast and accurate detection of DNA markers.
- Can be used as a biological material
- Functions as an organic compound for research
- Suitable for life science applications
- Applied in the design of DNA marker detection probes
Medchemexpress LLC 2-(2'-Pyridyl)benzimidazole | 1137-68-4 | 99.9% | 195.22 | 25 G
2-(2'-Pyridyl)benzimidazole is a potentially tridentate ligand capable of forming stable complexes with various transition metal ions. It functions as an anti-inflammatory agent and an inhibitor of *Escherichia coli* methionine aminopeptidase.
- Potentially tridentate ligand that can form stable complexes with various transition metal ions.
- Can be used as an anti-inflammatory agent.
- Functions as an inhibitor of *Escherichia coli* methionine aminopeptidase.
Medchemexpress LLC m-PEG12-Thiol | 2413368-61-1 | 95.0% | C25H52O12S | 250 MG
m-PEG12-Thiol is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and has not been fully validated for medical applications.
- Used in the synthesis of PROTACs
- PEG-based linker
- Exploits the ubiquitin-proteasome system
- For research use only
- Relevant to cancer and cancer targeted therapy research
Medchemexpress LLC 1-Methyl-5-mercapto-1,2,3,4-tetrazole-d3 | 345909-96-8 | 99.9% | 119.16 | 5 MG
1-Methyl-5-mercapto-1,2,3,4-tetrazole-d3 is the deuterium labeled 1-Methyl-1H-tetrazole-5-thiol. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Real Thiol | 2280796-90-7 | 98.37% | 411.36 | 1 MG
Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
- Provides ratiometric fluorescence responses with a wide dynamic range when reacting with glutathione.
- Has improved quantum yields and photostability.
- Allows monitoring of glutathione level changes within 1 to 10 mM in both directions in living cells.