Azolines
Apexbio Technology LLC Irbesartan 138402-11-6 25mg
Irbesartan (CAS 138402-11-6) is a small molecule antagonist of the angiotensin II type 1 (AT1) receptor By selectively blocking AT1 receptor activity irbesartan inhibits angiotensin II-induced vasoconstriction thereby promoting vasodilation and reducing blood pressure In biomedical research irbesartan serves as an important pharmacological tool to investigate cardiovascular regulation hypertension pathogenesis and related signaling pathways Additionally its use extends to studies exploring therapeutic strategies for cardiovascular disorders
Medchemexpress LLC N-acetyl-glucosamine thiazoline | 179030-22-9 | MFCD22376563 | >95.0% | C8H13NO4S | 10MG
N-acetyl-glucosamine thiazoline (NAG-thiazoline) is a small-molecule inhibitor of O-GlcNAcase used in biochemical and enzymology research to probe O-GlcNAc removal and GH20 family GlcNAcase activity. It shows potent biochemical inhibition against O-GlcNAcase and measurable activity versus bacterial GH20 GlcNAcase.
- Selective O-GlcNAcase inhibition for mechanistic studies.
- Documented biochemical potency (Ki ≈ 180 nM) against O-GlcNAcase.
- Activity data available versus GH20 GlcNAcase (IC50 ≈ 11.9 μM).
- Suitable for enzymology assays and pathway probing.
- Available as solid and in solution formats for assay flexibility.
- Molecular formula C8H13NO4S; CAS 179030-22-9.
Sigma Aldrich Fine Chemicals Biosciences RO-3306 | 872573-93-8 | MFCD17392573 | 5mg
RO-3306 | Purity: 98% | Mol Wt: 351.45 | 872573-93-8 | MFCD17392573 | 5mg
eMolecules 3-Bromopyridine-2-thiol | 65938-86-5 | 1G | Purity: 98%
Combi-Blocks | 3-Bromopyridine-2-thiol | 1G | 65938-86-5 | MFCD14651478
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eMolecules 5-BROMOPYRIDINE-3-THIOL HCL | | | 1g
AstaTech | 5-BROMOPYRIDINE-3-THIOL HCL | 1g | 596334531 | AT25650 | 95.000 | | | 226.520 | C5H5BrClNS
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eMolecules Methyl 3-amino-4-(isopropylamino)benzoate | 511240-22-5 | MFCD01570644 | 1g
Combi-Blocks | Methyl 3-amino-4-(isopropylamino)benzoate | 1g | 205414519 | WZ-9016 | 96.000 | 511240-22-5 | MFCD01570644 | 208.261 | C11H16N2O2
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FUJIFILM BIOSCIENCES INC 1 3-BIS(2-OXAZOLIN-2-YL)BENZEN
*Orders for this supplier are non-cancellable/non-returnable once they are processed.* 1,3-Bis(2-oxazolin-2-yl)benzene 500GR
Medchemexpress LLC 1-Methyl-5-mercapto-1,2,3,4-tetrazole-d3 | 345909-96-8 | 99.9% | 119.16 | 10 MG
1-Methyl-5-mercapto-1,2,3,4-tetrazole-d3 is a deuterium-labeled stable isotope of 1-Methyl-1H-tetrazole-5-thiol. It is intended for research use only and can be utilized as a tracer or an internal standard for quantitative analysis. Deuterium substitution in drug molecules is being studied for its potential impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC L-homocysteine thiolactone hydrochloride | 31828-68-9 | MFCD00065494 | 100.0% | 153.63 g·mol⁻¹ | C4H8ClNOS | 25 MG
L-Homocysteine thiolactone hydrochloride is the intramolecular thioester of homocysteine supplied as a research reagent. It functions as an amine-reactive compound used to probe homocysteine metabolism and protein post-translational modification in biochemical and cellular studies.
- Acts as an amine-reactive agent that can modify lysine residues.
- Used to study homocysteine metabolism and protein incorporation.
- Molecular formula: C4H8ClNOS; molecular weight: 153.63 g·mol⁻¹.
- CAS number: 31828-68-9.
- High stated purity (≈99.99%).
- Available in small pack sizes such as 25 mg for laboratory use.
Medchemexpress LLC Thiol-PEG-CH2COOH (MW 2000) | 95.0% | 50 MG
Thiol-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker. It features a thiol group at one end and a carboxymethyl group at the other, making it suitable for crosslinking and PROTAC synthesis. This compound is used in laboratory research for various applications requiring specific chemical modifications and conjugation.
- PROTAC linker
- Thiol-functionalized
- Carboxymethyl-functionalized
- Used in synthesis of PROTACs
- Molecular weight of 2000
- Purity of 95.0%
- Storage as powder at -20°C for 3 years
- Storage in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Thiol-PEG3-acid | 1347750-82-6 | ≥95.0% | 238.30 | 250 MG
Thiol-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and one for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
- Purity of ≥95.0%
- Molecular weight of 238.30
- CAS number 1347750-82-6
Medchemexpress LLC Thiol-PEG-acetic acid (SH-PEG-COOH) | 00-00-0 | 95.0% | HSC2H4O(C2H4O)nCH2CO2H | 10MG
Thiol-PEG-CH2COOH (MW 5000) is a heterobifunctional polyethylene glycol linker bearing a thiol at one terminus and a carboxylic acid at the other. It provides a flexible spacer for PROTAC assembly and other bioconjugation workflows, enabling orthogonal attachment strategies while maintaining solubility and spacer length control.