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Aromatic organic heterocyclic compounds that consist of benzene fused with a diazepine ring; diazepine rings are seven-membered heterocyclic compounds with two nitrogen atoms.
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FAUC 365 is a selective dopamine D3 receptor antagonist used as a research reagent to probe D3-mediated signaling in neuropharmacology and CNS disease models.
Highly selective dopamine D3 receptor antagonist (Ki = 0.5 nM).
Lower potency at related receptors (D4.4 Ki ≈ 340 nM; D2short Ki ≈ 2,600 nM; D2Long Ki ≈ 3,600 nM).
Chemical formula C23H25Cl2N3OS; molecular weight 462.44 g/mol.
Purity ~98.8% as supplied.
Appearance: off-white to light yellow solid.
Storage: powder -20°C for long-term storage; 4°C for shorter term.
Supplied as 25 mg research quantity.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
FAUC 365 is a research chemical described as a dopamine D3 receptor-selective antagonist used for in vitro pharmacology and receptor-binding studies. It is supplied in solid form and as a DMSO solution for biochemical assays.
Dopamine D3 receptor-selective antagonist.
High potency with reported Ki ≈ 0.5 nM at D3.
Purity 98.8%.
Chemical formula C23H25Cl2N3OS; molecular weight 462.44 g·mol⁻¹.
Available in small pack sizes, including 100 mg, and solution formats.
For research use only; not for human or clinical use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More