Benzodiazepines
Selleck Chemical LLC Clozapine S2459-1g
Clozapine (HF 1854 LX 100-129) is an atypical antipsychotic drug by acting as a 5-HT antagonist used in the treatment of schizophrenia
Medchemexpress LLC Clozapine | 5786-21-0 | MFCD00153785 | ≥98.0% | 326.82 g/mol | C18H19ClN4 | 5 MG
Clozapine (Standard) is an analytical reference standard of clozapine (CAS 5786-21-0) intended for laboratory use in method development, calibration, and quality control. It provides a characterized sample for assay verification and instrumental calibration in pharmaceutical and research settings.
- Used as an analytical reference standard for assay calibration.
- Suitable for method validation and quality control.
- High purity (≥98.0%) for reliable analytical results.
- Molecular weight 326.82 g/mol and formula C18H19ClN4 for identification.
- Supplied as a small, accurately weighed quantity for analytical workflows.
Medchemexpress LLC Clozapine N-oxide | 34233-69-7 | 99.9% | 342.82 | 25 MG
Clozapine N-oxide is a major metabolite of Clozapine, acting as an agonist for human muscarinic designer receptors (DREADDs). It activates the hM3Dq and hM4Di DREADD receptors, but it cannot cross the blood-brain barrier. Its parent compound, Clozapine, is a potent dopamine antagonist and a selective muscarinic M4 receptor agonist.
- Activates DREADD receptors hM3Dq and hM4Di
- Cannot cross the blood-brain barrier
- Metabolite of Clozapine
- Solid appearance
- Light yellow to yellow color
Medchemexpress LLC Coelenterazine | 55779-48-1 | 98.59% | 423.46 | 1 MG
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. It is used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is also a superoxide anion-sensitive chemiluminescent probe and can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Luminescent enzyme substrate for apoaequorin and Renilla luciferase.
- Used as a bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions.
- Superoxide anion-sensitive chemiluminescent probe.
- Can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Measurement of free radical production.
Alkali Scientific Coelenterazine, Native, 1 Milligram
Coelenterazine (1 mg) is a luminescent substrate, laboratory grade, commonly used in bioluminescence assays. This substrate is employed in molecular biology research for the detection and quantification of luciferase activity. Coelenterazine is a substrate for the luciferase enzyme, resulting in light emission when it is metabolized. This reagent is widely used in assays to study gene expression, protein interaction, and various biochemical reactions in cells. It is particularly useful in luminescent reporter assays for tracking cellular processes, drug screening, and biotechnological applications that require precise measurements of biological activity.
Medchemexpress LLC Coelenteramine 400a | 70217-82-2 | MFCD04114093 | 99.7% | 391.5 g/mol | C26H21N3O | 25 MG
Coelenteramine 400a is a coelenterazine-derived luciferase substrate used for Renilla luciferase (RLuc) assays and bioluminescence resonance energy transfer (BRET) research. It produces blue bioluminescent emission with a peak near 395 nm and is supplied as a solid with high reported purity.
- Provides blue emission with peak near 395 nm.
- Suitable for Renilla luciferase (RLuc) assays and BRET research.
- High reported purity (99.7%).
- Supplied as a solid; store protected from light at -20°C.
- Available in small laboratory quantities (25 MG).
- Follow safety data sheet precautions; harmful if swallowed and may irritate skin, eyes, and respiratory system.
Prolume Ltd Coelenterazine 400a | 70217-82-2 | 2 x 500 ug vials
Coelenterazine 400a | 70217-82-2 | 2 x 500 ug vials
Medchemexpress LLC Coelenterazine | 55779-48-1 | 98.59% | 423.46 | 50 MG
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. It has been utilized as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) for detecting protein-protein interactions. Additionally, it serves as a superoxide anion-sensitive chemiluminescent probe for the chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Luminescent enzyme substrate for apoaequorin and Renilla luciferase
- Used as a bioluminescence donor in BRET to detect protein-protein interactions
- Superoxide anion-sensitive chemiluminescent probe
- Can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm)
Medchemexpress LLC Coelenterazine 400a | 70217-82-2 | MFCD04114093 | 99.7% | 391.46 g/mol | C26H21N3O | 1 MG
Coelenterazine 400a is a bisdeoxy derivative of coelenterazine that serves as a blue-emitting substrate for Renilla luciferase (RLuc). It is used in bioluminescence and BRET/BRET2 assays to provide sensitive reporter signals in the ~395-400 nm range.
- Blue emission with an approximate 395 nm peak, suitable for BRET/BRET2 studies.
- High reported purity for reproducible assay results.
- Appropriate for use as an RLuc substrate in luciferase reporter assays.
- Available in small research quantities for assay development.
- Synonymous with bisdeoxycoelenterazine and coelenteramine 400a.
Sigma Aldrich Fine Chemicals Biosciences Clozapine | 5786-21-0 | MFCD00153785 | 25MG
Clozapine | Mol Wt: 326.82 | 5786-21-0 | MFCD00153785 | 25MG