Benzodioxanes
Apexbio Technology LLC BODIPY 493/503 121207-31-6 50mg
BODIPY 493 503 (CAS 121207-31-6) is a fluorescent dye designed for specific labeling of intracellular neutral lipids It penetrates cell membranes and selectively associates with neutral lipid structures enabling visualization and detection of lipid droplets in cellular preparations BODIPY 493 503 exerts its activity via selective staining of intracellular neutral lipids In cell-based studies BODIPY 493 503 is used for fluorescence-based detection of lipid droplets within both live and fixed cells Based on these properties BODIPY 493 503 holds research potential in cell biology lipid metabolism research and related biomedical fields for studying lipid accumulation lipid metabolism dynamics and cellular lipid storage mechanisms
Medchemexpress LLC BI-3663 | 2341740-84-7 | 99.8% | 917.84 | 25 MG
BI-3663 is a highly selective PTK2/FAK PROTAC that uses Cereblon ligands to hijack E3 ligases for PTK2 degradation. It inhibits PTK2 with an IC50 of 18 nM. BI-3663 is composed of BI-4464 linked to Pomalidomide with a linker, and demonstrates anti-cancer activity. It potently degrades PTK2 in Hep3B2.1-7 cells and A549 cells.
- Highly selective PTK2/FAK PROTAC (DC50=30 nM)
- Inhibits PTK2 with an IC50 of 18 nM
- Exhibits anti-cancer activity
- Potently degrades PTK2 in Hep3B2.1-7 cells and A549 cells (pDC50s of 7.6 and 7.9, respectively)
- For research use only
Medchemexpress LLC BI-3663 | 2341740-84-7 | 99.84% | 917.84 | 1 ML
BI-3663 is a highly selective PTK2/FAK PROTAC that hijacks E3 ligases for PTK2 degradation using Cereblon ligands. It inhibits PTK2 with an IC50 of 18 nM. This PROTAC is formed by linking BI-4464 to Pomalidomide. It exhibits anti-cancer activity and potently degrades PTK2 in Hep3B2.1-7 and A549 cells.
- Highly selective PTK2/FAK PROTAC.
- Inhibits PTK2 with an IC50 of 18 nM.
- Utilizes Cereblon ligands for E3 ligase hijacking and PTK2 degradation.
- Exhibits anti-cancer activity.
- Potently degrades PTK2 in Hep3B2.1-7 and A549 cells.
Medchemexpress LLC BI-3663 | 2341740-84-7 | 99.8% | 917.84 | 100 MG
BI-3663 is a highly selective PTK2/FAK PROTAC (DC50=30 nM) that utilizes Cereblon ligands to hijack E3 ligases for PTK2 degradation. It inhibits PTK2 with an IC50 of 18 nM. BI-3663 is composed of BI-4464 (HY-124625) linked to Pomalidomide (HY-10984) with a linker, and demonstrates anti-cancer activity.
- Highly selective PTK2/FAK PROTAC
- Inhibits PTK2 with an IC50 of 18 nM
- Utilizes Cereblon ligands for PTK2 degradation
- Composed of BI-4464 linked to Pomalidomide with a linker
- Exhibits anti-cancer activity
- Potently degrades PTK2 in Hep3B2.1-7 cells and A549 cells
TARGETMOL CHEMICALS INC BODIPY 493/503 500MG
Also available in 10 mg 25 mg 50 mg 100 mg 200 mg and bulk. Please contact Fisher for quotes. BODIPY 493/503 (Pyrromethene 546) is a lipophilic fluorescent probe with Ex/Em of 493/503 nm. BODIPY 493/503 localizes to polar lipids and can be used to label cellular neutral lipid contents and for live and fixed cell applications. purity: 99%