Benzopyrans
Sigma Aldrich Fine Chemicals Biosciences (-)-Deguelin >98% (HPLC), powder | Purity: >98% (HPLC) | Mol Wt: 394.42 | 522-17-8 | MFCD01740600 | 5MG
(-)-Deguelin >98% (HPLC), powder | Purity: >98% (HPLC) | Mol Wt: 394.42 | 522-17-8 | MFCD01740600 | 5MG
Cayman Chemical Deguelin Enzyme Inhibitors
A rotenoid with diverse biological activities; inhibits mitochondrial complex I activity in bovine heart electron transport particles and phorbol 12-myristate 13-acetate-induced ODC activity in MCF-7 cells (IC50s = 6.9 and 11 nM, respectively); induces apoptosis in MCF-7 and SK-BR-3 cells at 100 nM; induces mortality in adult bruchid beetles (C. maculatus) from 10-500 ppm; induces nigrostriatal dopaminergic degeneration in rats at 6 mg/kg
AdipoGen Citrinin
Chemical. CAS 518-75-2. Formula C13H14O5. MW 250.3. Isolated from Penicillium citrinum strain FKI-4836. Antibiotic. Antiprotozoal. Antimicrobial. Cytotoxic and genotoxic in various mammalian cells. Mitochondrial permeability transition pore MPTP activator. Apoptosis inducer. ERK and JNK signaling pathways activator. Nephrotoxic mycotoxin. Suppresses NO and iNOS expression via inhibition of the JAK/STAT-1alpha and NF-kappaB signaling pathways. Tubulin polymerization and mitotic spindle assembly inhibitor. Increases reactive oxygen species ROS. Induces cell cycle arrest at the G0/G1 and G2/M phase.
Cayman Chemical Deguelin Enzyme Inhibitors
A rotenoid with diverse biological activities; inhibits mitochondrial complex I activity in bovine heart electron transport particles and phorbol 12-myristate 13-acetate-induced ODC activity in MCF-7 cells (IC50s = 6.9 and 11 nM, respectively); induces apoptosis in MCF-7 and SK-BR-3 cells at 100 nM; induces mortality in adult bruchid beetles (C. maculatus) from 10-500 ppm; induces nigrostriatal dopaminergic degeneration in rats at 6 mg/kg
