Benzoxadiazoles
Medchemexpress LLC Nbd-14270 | 2411819-82-2 | 99.5% | 425.43 | 50 MG
NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist. It binds to HIV-1 gp120 and demonstrates significant antiviral activity. This compound exhibits low cytotoxicity with a CC50 >100 μM, making it suitable for various research applications.
- Potent HIV-1 entry antagonist with IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses
- Binds to HIV-1 gp120
- Exhibits potent antiviral activity
- Low cytotoxicity (CC50 > 100 μM)
- Anti-HIV-1 activity (IC50=0.16 μM) in single-cycle (TZM-bl cells) assay
- No induced toxicity in U87-CD4-CXCR4 cell line at assay doses
Medchemexpress LLC 7-nitro-2,1,3-benzoxadiazol-4-ylamine | 10199-91-4 | 96.7% | 10 MG
NBD-amine (7-nitro-2,1,3-benzoxadiazol-4-ylamine) is a fluorogenic amine used as a fluorescent probe and a synthetic building block for labeling and sensing applications. It fluoresces weakly in water and strongly in organic solvents, membranes, and other hydrophobic environments. CAS 10199-91-4; purity ~96.7%.
- Fluorogenic amine that enhances fluorescence in hydrophobic environments.
- Useful for labeling, sensing, and probe development.
- Soluble in DMSO at 31.25 mg/mL; ultrasonic agitation may be needed.
- Powder stable at -20°C for up to 3 years.
- Molecular weight 180.12 g/mol; formula C6H4N4O3.
Medchemexpress LLC NBD-F (4-Fluoro-7-nitrobenzofurazan) | 29270-56-2 | 98.87% | 1 ML
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent developed for amino acid analysis. It reacts with primary or secondary amines to create a fluorescent product, which is used for the analysis of amino acids and low molecular weight amines. NBD-F is also applied in the analysis of other amino acid derivatives like N-methyl-D-aspartic acid and glutathione. This reagent offers a simple derivatization procedure and its derivatives are highly stable.
- Pro-fluorescent reagent developed for amino acid analysis.
- Reacts with primary or secondary amines to produce a fluorescent product.
- Used for analysis of amino acids and low molecular weight amines, and other amino acid derivatives.
- Simple derivatization procedure, and derivatives are highly stable.
- Appearance: solid.
- Color: light yellow to yellow.
- Emission (Em): 515.
- Excitation (Ex): 445.
Medchemexpress LLC Apelin-16, human, bovine acetate | 99.8% | 2010.37 | 1 MG
Apelin-16, human, bovine acetate is a biologically active peptide.
- Endogenous ligand for the G-protein-coupled APJ receptor.
- Produced as a pre-proprotein of 77 amino acids.
- One of the active fragments of Apelin.
Medchemexpress LLC NBD-557 | 333352-59-3 | 99.4% | C17H24BrN3O2 | 50 MG
NBD-557 is a potential HIV-1 inhibitor, exhibiting potent cell fusion and virus-cell fusion inhibitory activity. This small molecule targets viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the cellular receptor CD4, without affecting later stages of the HIV-1 life cycle like reverse transcriptase, integrase, or protease. It is active against both X4 and R5 viruses, and effective against HIV-1 laboratory-adapted strains, including an AZT-resistant strain, and HIV-1 primary isolates.
- Targets HIV-1 entry by inhibiting gp120 binding to CD4
- Does not inhibit reverse transcriptase, integrase, or protease
- Active against X4 and R5 viruses
- Effective against HIV-1 laboratory-adapted and primary isolates
- Binds to unliganded HIV-1 gp120
- For research use only
Medchemexpress LLC 7-Fluorobenzofurazan-4-sulfonic acid (ammonium) | 84806-27-9 | 99.0% | 25 MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label primarily used for detecting dissolved thiol-disulfide compounds such as Cys and GSH. It is suitable for various laboratory applications requiring fluorescence-based detection.
- Fluorescent label for thiol-disulfide detection
- Used with Cys and GSH
- Research use only
- Excitation wavelength range: 451-495 nm Blue
- Emission wavelength range: 451-495 nm Blue
Medchemexpress LLC 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | 98.8% | 5 MG
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | 98.8% | 5 MG
Accela Chembio Inc 4-benzofurazancarboxaldehyde | 1g | 32863-32-4 | MFCD07772900 | 97+% | Shelf Life: 1980 Days | Light Sensitive/air Sensitive/+4
4-benzofurazancarboxaldehyde | 1g | 32863-32-4 | MFCD07772900 | 97+% | Shelf Life: 1980 Days | Light Sensitive/air Sensitive/+4
AdipoGen NBD dodecanoic acid N-SE
Chemical. CAS 689263-76-1. Formula C22H29N5O7. MW 475.5. Synthetic. Suitable for probing the ligand binding sites of fatty acid and sterol carrier proteins as well as the investigation of lipolysis processes.
Selleck Chemical LLC NBD-556-E0943-5MG
NBD-556 is a novel human immunodeficiency virus type 1 (HIV-1) entry inhibitor that block the gp120-CD4 interaction