Benzoxadiazoles
Medchemexpress LLC Nbd-14270 | 2411819-82-2 | 99.5% | 425.43 | C18H18F3N5O2S | 5 MG
NBD-14270 is a pyridine analogue that functions as a potent HIV-1 entry antagonist by binding to the gp120 envelope protein. It exhibits sub-micromolar antiviral activity with low cytotoxicity and is provided for research applications with characterized purity, formula, and storage recommendations.
- High purity: 99.53%.
- Chemical formula: C18H18F3N5O2S; molecular weight: 425.43.
- CAS number: 2411819-82-2.
- Recommended solvent: DMSO; use ultrasonic aid for dissolution.
- Storage: solid at 4°C; in solvent store at -80°C for long-term stability.
- Typical applications: in vitro antiviral and HIV-1 entry assays.
Apexbio Technology LLC NBD-Cl 10199-89-0 500mg
NBD-Cl (10199-89-0) is a fluorescent labeling reagent that covalently reacts with nucleophilic groups specifically amines and thiols It is designed to derivatize these functional groups enabling detection through the formation of highly fluorescent conjugates NBD-Cl exerts its biological utility primarily through its electrophilic reaction mechanism with free amino and thiol groups in biomolecules No specific experimental model or quantitative activity metric is provided Based on these chemical properties NBD-Cl holds research potential in the labeling and detection of amino acid residues peptides proteins and thiol-containing enzymes as well as in studies of enzyme activities and biomolecular interactions
![Medchemexpress LLC Hexanamide, N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-6-[(7-nitro | 94885-03-7 | 98.0% | 737.88 g·mol⁻¹ | C36H59N5O11 | 100 UG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000285210.png-250.jpg)
Medchemexpress LLC Hexanamide, N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-6-[(7-nitro | 94885-03-7 | 98.0% | 737.88 g·mol⁻¹ | C36H59N5O11 | 100 UG
C6 NBD Glucosylceramide is a fluorescently labeled glucosylceramide derivative used to investigate sphingolipid metabolism and intracellular trafficking. The NBD fluorophore on a C6 acyl chain provides fluorescence properties suitable for imaging and plate-based assays, and the material is supplied at high purity for biochemical experiments.
- Fluorescent label suitable for microscopy and plate assays.
- Excitation 466 nm and emission 535 nm for standard fluorescence setups.
- High purity suitable for biochemical and enzymatic assays (98.0%).
- Useful for studying glucosylceramide metabolism and internalization.
- Available in small-scale vials ideal for research applications (100 μg, 500 μg).
Sigma Aldrich Fine Chemicals Biosciences 7-Fluorobenzofurazan-4-sulfonic acid ammonium salt >=98% | 84806-27-9 | MFCD02682109 | 10MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium salt >=98% | Purity: >=98% | Mol Wt: 235.19 | 84806-27-9 | MFCD02682109 | 10MG
Medchemexpress LLC 6alpha-ethyl-3alpha,7alpha,23-trihydroxy-24-nor-5beta-cholan-23-sulfate sodium salt | 1000403-03-1 | 98.0% | 494.7 g/mol | C25H43NaO6S | 1MG
INT-767 is a semisynthetic bile acid-derived small molecule used in preclinical research as a potent dual agonist of the farnesoid X receptor (FXR) and the G protein-coupled bile acid receptor TGR5. It modulates bile acid signaling and has been studied in liver and metabolic disease models in vitro and in vivo.
Medchemexpress LLC 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | MFCD00036687 | 98.8% | 217.18 | C6H4FN3O3S | 10 MG
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole is a fluorescent reagent for the sensitive and specific detection of thiols. It offers low background fluorescence and a stable fluorophore, making it suitable for thiol derivatization and fluorescence-based analytical applications. The compound is typically supplied as a yellow to green solid and should be protected from light during storage.
- Provides sensitive and specific fluorescence-based thiol detection.
- Low fluorescence background for improved signal-to-noise.
- Stable fluorophore under recommended storage conditions.
- Supplied in small, lab-scale quantities for analytical use.
- Yellow to green solid, easy to handle and store.
Medchemexpress LLC NBD-14189 | 2234273-72-2 | 99.8% | C18H16F4N4O2S | 10MG
NBD-14189 is a small-molecule HIV-1 entry antagonist that binds the viral gp120 envelope protein and blocks virus entry. It shows potent activity in cell-based assays (IC50 ≈ 89 nM against HIV-1 HXB2 pseudovirus; antiviral EC50 <200 nM) and is supplied as a high-purity research compound for in vitro studies.
- Potent gp120-directed entry antagonist with IC50 ≈ 89 nM.
- Demonstrated antiviral activity in cell assays (EC50 <200 nM).
- High purity suitable for research use (≈99.8%).
- Supplied as solid and as 10 mM solution in DMSO for screening.
- Molecular formula C18H16F4N4O2S and molecular weight 428.40 g·mol⁻1.
- Recommended storage: 4°C sealed; in solvent store at -80°C for long term.
eMolecules Medchem Express / MBD / 100mg / 642185116 / HY-141667 / / 33984-50-8 / MFCD00042778 / 300.274 / C14H12N4O4
Medchem Express / MBD / 100mg / 642185116 / HY-141667 / / 33984-50-8 / MFCD00042778 / 300.274 / C14H12N4O4
Medchemexpress LLC N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-phosphatidylethanolamine, triethylammonium salt | 178119-00-1 | MFCD00467850 | 95.0% | 956.26 g/mol | C49H90N5O11P | 10 MG
NBD-PE is an NBD-labeled phosphatidylethanolamine fluorescent probe used to label membranes and monitor lipid trafficking and membrane dynamics. It exhibits environment-sensitive green fluorescence (excitation ~463 nm, emission ~526 nm) and is supplied as a solid for laboratory use. CAS 178119-00-1; molecular weight ~956.26 g/mol.
- Green fluorescent NBD label with excitation ~463 nm and emission ~526 nm.
- Integrates into lipid bilayers for membrane labeling and tracking.
- Environment-sensitive fluorescence suitable for monitoring membrane order.
- Available in small laboratory quantities for experimental use.
- Supplied as a solid with a brown to black physical appearance.
- CAS 178119-00-1; molecular weight 956.26 g/mol.