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1

Medchemexpress LLC Cbp/p300-in-3 | 2299226-01-8 | 98.0% | 431.53 g/mol | C24H29N7O | 5 MG

CBP/p300-IN-3 is a small-molecule inhibitor of the p300/CBP histone acetyltransferases (HATs), described as Compound 6 in patent WO 2019049061 A1. The compound is supplied for research use and is accompanied by analytical documentation and safety information.

  • Small-molecule inhibitor of p300/CBP histone acetyltransferases.
  • High chemical purity (98.0%).
  • Molecular formula C24H29N7O and molecular weight 431.53 g/mol.
  • Available in multiple pack sizes, including 5 mg.
  • Accompanied by COA, SDS, and data sheet documentation.
  • Intended for research use only.

ENCOMPASS_PREFERRED
2

Medchemexpress LLC Protac CBP/p300 degrader-1 | 2484739-48-0 | 98.3% | 893.98 | C46H53F2N11O6 | 5 MG

PROTAC CBP/P300 Degrader-1 is a small-molecule proteolysis targeting chimera designed to induce selective degradation of the epigenetic coactivators CBP and p300. It demonstrates potent degradation activity and reduces viability in multiple cancer cell lines, and is intended for research use in cellular and biochemical assays.

  • Targets and degrades CBP and p300 in cell-based assays.
  • Potently inhibits viability of multiple cancer cell lines.
  • Molecular formula C46H53F2N11O6.
  • Molecular weight 893.98 Da.
  • Supplied in milligram quantities for research applications.

ENCOMPASS_PREFERRED
3

Medchemexpress LLC Protac CBP/P300 degrader-1 | 2484739-48-0 | Not specified | >95.0% | C46H53F2N11O6 | 10MG

PROTAC CBP/P300 Degrader-1 is a small-molecule proteolysis-targeting chimera that selectively induces degradation of the epigenetic reader proteins CBP and p300. It has been reported to potently inhibit cell viability in multiple cancer cell lines and is provided for research use only.

  • Targets CBP and p300 epigenetic reader domain.
  • Degrades target proteins via PROTAC mechanism.
  • Reported to inhibit viability of multiple cancer cell lines.
  • Molecular formula C46H53F2N11O6; molecular weight 893.98.
  • High solubility in DMSO (173.33 mg/mL); in vivo suspended solubility 6.5 mg/mL.
  • Storage: in solvent -80°C up to 6 months, -20°C up to 1 month; keep sealed, away from moisture and light.
  • Intended for laboratory research use only; not for human administration.

ENCOMPASS_PREFERRED