Biotin and derivatives
Medchemexpress LLC Bis-PEG6-NHS ester | 1526718-98-8 | MFCD24539464 | 98.0% | 576.55 | C24H36N2O14 | 5 G
Bis-PEG6-NHS ester is a PEG6-based bifunctional NHS-ester linker used to assemble PROTACs and as a cleavable linker in antibody-drug conjugate synthesis. It reacts with primary amines to form amide bonds, and the PEG6 spacer improves hydrophilicity and flexibility.
- Peg6 spacer provides flexibility and hydrophilicity.
- NHS ester functional groups react with primary amines for conjugation.
- Cleavable linker suitable for ADC and PROTAC synthesis.
- High purity (98.0%) and molecular weight 576.55.
- Soluble in DMSO at 125 mg/mL; ultrasonic recommended.
- Hygroscopic; store sealed at -20°C and prepare solutions freshly.
Medchemexpress LLC Biotin-LC-LC-NHS | 89889-52-1 | 98.0% | 567.7 g/mol | C26H41N5O7S | 50 MG
Biotin-LC-LC-NHS is a long-chain N-hydroxysuccinimide (NHS) activated biotinylation reagent used to label proteins, antibodies, and small molecules. The LC-LC spacer reduces steric hindrance during conjugation, and the NHS ester reacts with primary amines to form stable amide bonds.
- Provides long-chain spacer (LC-LC) to reduce steric hindrance.
- Reactive NHS ester for amine-selective conjugation.
- Suitable for labeling antibodies and small molecules.
- Solid, white to light yellow appearance; store under inert gas and protect from light.
- Soluble in DMSO; follow recommended solvent and storage guidance.
Medchemexpress LLC DBCO-biotin | 1418217-95-4 | MFCD22380751 | 98.5% | 502.63 g·mol⁻1 | C28H30N4O3S | 10MG
DBCO-Biotin is a bifunctional click-chemistry reagent that links a dibenzocyclooctyne (DBCO) reactive moiety to a biotin affinity tag, enabling copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) for bioconjugation and probe development. Supplied as a high-purity solid for laboratory research, it is commonly used in bioconjugation, affinity enrichment, and linker synthesis applications.
- Enables copper-free click chemistry via DBCO-mediated SPAAC.
- Provides a biotin tag for affinity capture and detection.
- High purity suitable for sensitive bioconjugation workflows.
- Available in small mg-scale quantities for research use.
- Stable when stored under recommended conditions; consult safety data for handling.
![Medchemexpress LLC N-[6-(biotinamido)hexyl]-3-(2-pyridyldithio)propionamide | 129179-83-5 | MFCD00078541 | 99.7% | C24H37N5O3S3 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259744.png-250.jpg)
Medchemexpress LLC N-[6-(biotinamido)hexyl]-3-(2-pyridyldithio)propionamide | 129179-83-5 | MFCD00078541 | 99.7% | C24H37N5O3S3 | 10MG
Biotin-HPDP is a thiol-reactive biotinylation reagent that labels free protein thiols through a cleavable disulfide linkage, enabling reversible biotinylation for affinity purification and recovery of native proteins. It is supplied as a white to off-white solid with high reported purity and defined storage recommendations.
- Thiol-reactive biotinylation reagent for cysteine labeling.
- Cleavable disulfide linkage enables reversible labeling.
- Suitable for affinity purification and protein recovery.
- High reported purity (99.7%).
- Stable as powder at -20°C for long-term storage.
- Available in small pack sizes for biochemical assays.
Apexbio Technology LLC HyperFluor™ 555 NHS Ester 1mg
HyperFluor 555 NHS Ester is a fluorescent labeling reagent targeting primary amines (R NH ) on biomolecules It is designed to facilitate covalent conjugation with proteins amine-modified oligonucleotides and other primary amine-containing biomolecules via its NHS ester moiety HyperFluor 555 NHS Ester exerts its activity through amine-specific covalent labeling Based on these properties HyperFluor 555 NHS Ester holds research potential in fluorescence microscopy and flow cytometry for labeling and detection of proteins and oligonucleotides