Biotin and derivatives
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Medchemexpress LLC Biotin-PEG5-NHS ester | 98.0% | 632.72 | 100 MG
Biotin-PEG5-NHS ester is a heterobifunctional crosslinker and a polyethylene glycol-containing bioconjugation reagent. It is used in scientific research for constructing highly sensitive biosensors, developing targeted drug delivery systems (e.g., liposome modification), immunofluorescence imaging, and protein affinity purification. It serves as a tool for precise labeling and functionalization of biomolecules.
- Heterobifunctional crosslinker.
- Polyethylene glycol-containing bioconjugation reagent.
- Specific introduction of biotin tags onto molecules with primary amine groups (-NH2), such as proteins, antibodies, and polypeptides, or material surfaces.
- NHS ester group reacts rapidly with amine groups under mild conditions to form stable amide bonds.
- Intermediate PEG5 chain acts as a flexible spacer arm, increasing spatial freedom and improving water solubility while reducing non-specific adsorption.
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