Biotin and derivatives
![eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 490500208](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000471012.jpg-250.jpg)
eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 490500208
Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 490500208
Medchemexpress LLC Pentanediamide, N1-[4-[[4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo... | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 g/mol | C56H80N12O9S | 50 MG
Ibrutinib-biotin is a biotin-conjugated chemical probe derived from the BTK inhibitor ibrutinib. It features ibrutinib linked to biotin via a long-chain linker and is designed for target engagement, affinity pull-downs, and assay development directed at Bruton's tyrosine kinase (BTK).
- Biotin-conjugated probe for affinity capture and pull-down assays.
- Derived from a BTK inhibitor for target-specific engagement.
- Low-nanomolar potency against BTK (IC50 0.755-1.02 nM).
- High purity suitable for research applications (>99.6%).
- Available as solid material and as a 10 mM solution in DMSO.
- Molecular weight approximately 1,097.37 g/mol.
eMolecules 756525-90-3 | m-PEG8-NHS ester | Ambeed | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 5g | 714088006
m-PEG8-NHS ester | Ambeed | 756525-90-3 | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 5g | 714088006
Medchemexpress LLC Bis-PEG21 N-hydroxysuccinimide ester | 2221948-98-5 | 98.0% | 1237.34 | C54H96N2O29 | 50 MG
Bis-PEG21 N-hydroxysuccinimide ester is a polyethylene glycol (PEG21) based homobifunctional NHS ester linker used for bioconjugation. It provides two reactive NHS ester termini for amine coupling and a long PEG spacer to increase solubility and flexibility, making it suitable for PROTAC and antibody-drug conjugate (ADC) synthesis.
- PEG21 spacer increases solubility and molecular flexibility.
- Two NHS ester groups enable efficient amine coupling.
- Suitable as a cleavable linker in ADC and PROTAC applications.
- High purity with analytical data and a certificate of analysis available.
- Available in multiple pack sizes; supplier data notes a 50 MG pack though manufacturer lists 100 MG as the smallest standard pack.
Medchemexpress LLC N-piperidine ibrutinib hydrochloride | 2231747-18-3 | 98.1% | C22H23ClN6O | 10MG
N-piperidine ibrutinib hydrochloride is a hydrochloride salt derivative used in research as a BTK ligand and synthetic intermediate for targeted degraders. It is supplied as a high-purity solid and as a ready-to-use DMSO solution, and is characterized for potency against wild-type and mutant BTK.
- Potent BTK activity with low-nanomolar IC50s for WT and C481S variants.
- High purity suitable for research applications.
- Available as solid powder and 10 mM solution in DMSO.
- White to yellow solid appearance for easy handling.
- Useful as a ligand in PROTAC synthesis and other chemical biology workflows.
Medchemexpress LLC Azido-PEG6-NHS ester | 2055014-64-5 | 98.0% | 250 MG
Azido-PEG6-NHS ester is a cleavable PEG ADC linker. It is also a PEG- and alkyl/ether-based PROTAC linker. This compound is a click chemistry reagent, featuring an azide group for copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- Cleavable PEG ADC linker
- Used in antibody-drug conjugate (ADC) synthesis
- PEG- and alkyl/ether-based PROTAC linker
- Suitable for PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
Medchemexpress LLC Dota-NHS-ester TFA | 95.0% | 25 MG
DOTA-NHS-ester (TFA) is a versatile linker for affibody molecules, essential in various imaging techniques such as small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. It is also used for labeling radiotracers or imaging probes, particularly for tumor detection research.
- Used as a linker for affibody molecules
- Applicable in small animal PET, SPECT, and CT scanning
- Labels radiotracers or imaging probes for tumor detection
- For research use only
- Supplied as a solid, white to off-white in color
- Molecular weight: 615.51
- Formula: C22H32F3N5O12
- Storage: -20°C, sealed, away from moisture
- Solubility (in vitro): DMSO at 125 mg/mL (203.08 mM), requires ultrasonic
Medchemexpress LLC Amine-PEG3-Biotin | 359860-27-8 | 99.8% | 418.55 | 50 MG
Amine-PEG3-Biotin is a signal amplification label that contains a biotin group and a terminal primary amine group, intended for research use only.
- Contains a biotin group and a terminal primary amine group.
- Appears as a white to off-white solid.
- Store at -20°C, protected from light. If in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
- Soluble in H2O at 200 mg/mL (477.84 mM) and DMSO at 100 mg/mL (238.92 mM), with sonication required.