Biotin and derivatives
Medchemexpress LLC L-Biotin | 21788-37-4 | 99.5% | 244.31 g/mol | C10H16N2O3S | 5 MG
L-Biotin is the unnatural enantiomer of biotin supplied for research use. It is provided as a solid and as a 10 mM solution in DMSO, with analytical and safety documentation available.
- High reported purity (≈99.5%).
- Available in small solid quantities (5 mg, 10 mg, 25 mg) and solution form.
- Suitable as a biochemical reagent and reference compound for in vitro assays.
- COA and SDS provided for quality and safety information.
![eMolecules 943858-70-6 | Azidobutyric acid NHS ester | Broadpharm | MFCD22573606 | 226.192 | C8H10N4O4 | 95.000 | [N-]=[N+]=NCCCC(=O)ON1C(=O)CCC1=O | 500mg | 779523831](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000126046.jpg-250.jpg)
eMolecules 943858-70-6 | Azidobutyric acid NHS ester | Broadpharm | MFCD22573606 | 226.192 | C8H10N4O4 | 95.000 | [N-]=[N+]=NCCCC(=O)ON1C(=O)CCC1=O | 500mg | 779523831
Azidobutyric acid NHS ester | Broadpharm | 943858-70-6 | MFCD22573606 | 226.192 | C8H10N4O4 | 95.000 | [N-]=[N+]=NCCCC(=O)ON1C(=O)CCC1=O | 500mg | 779523831
Medchemexpress LLC M-PEG13-NHS ester | 3063847-98-0 | 95.0% | C32H59NO17 | 50 MG
M-PEG13-NHS ester is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs, which are molecules designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Can be used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC (+)-Biotin 4-nitrophenyl ester | 33755-53-2 | ≥98.0% | 500 MG
(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be utilized in the synthesis of PROTACs. This mechanism leverages the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PROTACs consist of two distinct ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase.
- The other ligand targets the protein intended for degradation.
eMolecules 854601-60-8 | m-PEG11-amine | Broadpharm | MFCD27977521 | 515.641 | C23H49NO11 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 1g | 229582239
m-PEG11-amine | Broadpharm | 854601-60-8 | MFCD27977521 | 515.641 | C23H49NO11 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 1g | 229582239
Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate | 107348-47-0 | MFCD28398150 | 98.0% | 326.40 g/mol | C13H14N2O4S2 | 50 MG
PPC-NHS ester is a cleavable linker reagent containing an N-hydroxysuccinimide (NHS) ester and a pyridin-2-yldisulfanyl cleavable moiety; it is used to attach cytotoxic payloads to antibodies and enable payload release under reducing conditions.
- Cleavable disulfide linker enabling intracellular release of payloads
- N-hydroxysuccinimide (NHS) ester reactive toward primary amines
- Molecular formula C13H14N2O4S2, molecular weight 326.40 g/mol
- Purity 98.0%
- Supplied as a white to off-white solid, 50 MG per package
- Storage: powder -20°C (stable 3 years); in solvent -80°C (6 months), -20°C (1 month)
eMolecules 756525-90-3 | m-PEG8-NHS ester | Ambeed | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 714088003
m-PEG8-NHS ester | Ambeed | 756525-90-3 | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 714088003
Medchemexpress LLC Biotin-PEG3-iodoacetamide | 2306161-26-0 | 97.0% | 10 MG
Biotin-PEG3-iodoacetamide is a PEG-based linker combining a biotin tag, a three-unit PEG spacer, and an iodoacetamide reactive group. It selectively alkylates cysteine residues under mild conditions to introduce a biotin handle for affinity capture, detection, and enrichment workflows.
- Selective cysteine labeling via iodoacetamide chemistry.
- Biotin tag enables high-affinity streptavidin capture.
- PEG3 spacer improves solubility and reduces steric hindrance.
- Suitable for protein labeling, pull-downs, and detection assays.
- Provided as a small-molecule reagent for research use.
Medchemexpress LLC Diazo biotin-PEG3-azide | 1339202-33-3 | MFCD28334530 | 95.5% | C33H45N9O7S | 10MG
Diazo biotin-PEG3-azide is a multifunctional PEG3 linker combining a cleavable diazo functional group, a biotin affinity tag, and an azide reactive handle. It is designed for efficient biotinylation and capture of alkyne-bearing biomolecules using click chemistry and for use as a linker in chemical biology workflows.
- Provides azide functionality for CuAAC and SPAAC click reactions.
- Includes a biotin tag for affinity purification and detection.
- Contains a diazo group enabling photo-cleavage or crosslinking.
- PEG3 spacer improves solubility and reduces steric hindrance.
- Suitable for biotinylation, pull-down assays, and linker synthesis.
Medchemexpress LLC (+)-Biotin 4-nitrophenyl ester | 33755-53-2 | ≥98.0% | 250 MG
(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Biotin-DADOO TFA | 194920-57-5 | 95.0% | 250 MG
Biotin-DADOO TFA is a biotinylating reagent that is conjugated to CMC thiosulfate.
- Can be utilized to synthesize biotin-estradiol conjugates.
- Used for the determination of plasma estradiol concentrations by enzyme immunoassay.
- Appearance: oil.
- Color: light yellow to brown.
- For research use only.
Medchemexpress LLC Biotin-PEG3-NHS ester | 1253286-56-4 | 98.4% | 25 MG
Biotin-PEG3-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTAC.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
Medchemexpress LLC Aeide-C1-NHS ester | 824426-32-6 | 98.0% | C6H6N4O4 | 100 MG
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Alkyl/ether-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Click chemistry reagent.
- Contains an Azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine) | 138529-46-1 | 98.0% | 500 MG
Biotin-DADOO is a biotin-containing amine compound and a biotinylation reagent. It acts as an amino component in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. This product can be conjugated with carboxymethyl cellulose derivatives and is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. It can also be utilized in influenza A research.
- Captures free influenza neuraminidase on streptavidin-coated polystyrene plates.
- Forms stable self-assembled monolayers (SAMs) on planar gold surfaces.
- Forms a stable biotin-estradiol conjugate.
Medchemexpress LLC Azido-PEG3-O-NHS ester | 2110448-98-9 | C13H20N4O8 | 50 MG
Azido-PEG3-O-NHS ester is a chemical substance identified as HY-140768 by MedChemExpress. It has a molecular weight of 360.32 and the chemical formula C13H20N4O8. This product is intended for laboratory use and substance manufacturing.
- Recommended for laboratory chemicals and manufacturing
- Keep container tightly sealed in cool, well-ventilated area
- Avoid direct sunlight and sources of ignition