Biotin and derivatives
Medchemexpress LLC Pomalidomide-C3-NHS ester | 2828476-87-3 | >98.7% | 456.41 | 100 MG
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker. It is for research use only and not sold to patients.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide-based cereblon ligand and NHS ester linker
- Targets cereblon
Medchemexpress LLC Pomalidomide-C3-NHS ester | 2828476-87-3 | 98.7% | 456.41 | 25 MG
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker. This product is for research use only and not sold to patients.
- Incorporates Pomalidomide based cereblon ligand
- Includes NHS ester linker
- Targets Cereblon
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC Pomalidomide-C3-NHS ester | 2828476-87-3 | 98.7% | 456.41 | 50 MG
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker. This product is intended for research use only.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Includes NHS ester linker
- Stable under recommended storage conditions
- Ships at room temperature in continental US
- Stores at 4°C, sealed, away from moisture
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC Pomalidomide-C3-NHS ester | 2828476-87-3 | 98.7% | 456.41 | 5 MG
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Pomalidomide based cereblon ligand and an NHS ester linker. This product is for research use only and is not sold to patients.
- E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Features an NHS ester linker
- Target: Cereblon
- Appearance: Solid, light yellow to yellow
- Soluble in DMSO
Medchemexpress LLC 3-Pyrrolidinesulfonic acid, 1-(acetyloxy)-2,5-dioxo- | 152305-87-8 | 98.0% | C6H7NO7S | 25 MG
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs are compounds containing two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Targets an E3 ubiquitin ligase
- Targets a specific protein
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
- Relevant to cancer research
- Relevant to cancer targeted therapy
- Classified as a PROTAC linker
- Functions as an inhibitor
Medchemexpress LLC Pomalidomide-C3-NHS ester | 2828476-87-3 | 98.7% | 456.41 g·mol⁻1 | C21H20N4O8 | 10 MG
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate that combines a cereblon-binding pomalidomide scaffold with an NHS-activated C3 linker. It is designed as a conjugation-ready building block for targeted protein degradation chemistry and other bioconjugation applications, supplied with high purity and recommended storage conditions for research use.
- E3 ligase recruiting building block for targeted protein degradation.
- NHS ester functionalized C3 linker for efficient amide coupling to amines.
- High purity (>98%) suitable for synthetic workflows.
- Soluble in DMSO at 100 mg/mL for convenient stock preparation.
- Offered in small research sizes, including 10 MG, for medicinal chemistry.
- Store sealed, away from moisture, with recommended cold storage for solutions.