Dioxolanes
Selleck Chemical LLC Ertugliflozin S5413-5mg
Ertugliflozin (MK-8835 PF-04971729) is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50 values of 0 877 nM for h-SGLT2 and 1000-fold higher for h-SGLT1
Cayman Chemical ErtuglIflozIn 10mg
An SGLT2 inhibitor (IC50 = 0.927 nM for the human enzyme); selective for SGLT2 over SGLT1 (IC50 = 2,050 nM for the human enzyme); increases urinary glucose excretion in rats in a dose-dependent manner
Medchemexpress LLC sparstolonin B | 1259330-61-4 | 268.22 g/mol | 10MG
sparstolonin B | 1259330-61-4 | 268.22 g/mol | 10MG
Medchemexpress LLC YG1702, 10mg | CAS No. : 724737-08-0 | Purity: 99.21%
YG1702 is a potent ALDH18A1-specific inhibitor. YG1702 attenuates the growth of MYCN-amplified NB and down-regulates MYCN. YG1702 physically interacts with ALDH18A1 with a high affinity and might potentially affect its enzymatic activity.
Medchemexpress LLC Brigimadlin (Synonyms: BI 907828) 10mg
Brigimadlin (BI 907828) is an orally active E3 ubiquitin-protein ligase MDM-2 inhibitor, preventing MDM-2 from negatively regulating the tumor suppressor p53. Brigimadlin can be used for antineoplastic research.
Apexbio Technology LLC Topiramate 97240-79-4 100mg
Topiramate (CAS 97240-79-4) is an anticonvulsant compound widely investigated for its interactions with multiple neuronal ion channels and neurotransmitter receptors including AMPA kainate and NMDA glutamate receptors as well as GABA A receptors and voltage-gated Na channels In vitro studies demonstrate that at submicromolar concentrations (IC 0 5 M) topiramate selectively inhibits GluR5-containing kainate receptor-mediated excitatory synaptic currents in rat basolateral amygdala neurons and partially attenuates AMPA receptor-mediated responses Electrophysiological assays in cortical slices reveal that topiramate modulates persistent Na currents and shifts steady-state inactivation In animal models topiramate confers dose-dependent neuroprotection in ischemic stroke and elevates seizure thresholds supporting its utility for mechanistic studies of epilepsy and neuroprotection
![eMolecules Ambeed / (1S2S3S4R5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-68-dioxabicyclo[3.2.1]octane-234-triol / 1mg / 534567123 / A191432 / / 1210344-57-2 / MFCD21609259 / 436.890 / C22H25ClO7](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502425569.JPG-250.jpg)
eMolecules Ambeed / (1S2S3S4R5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-68-dioxabicyclo[3.2.1]octane-234-triol / 1mg / 534567123 / A191432 / / 1210344-57-2 / MFCD21609259 / 436.890 / C22H25ClO7
Ambeed / (1S2S3S4R5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-68-dioxabicyclo[3.2.1]octane-234-triol / 1mg / 534567123 / A191432 / / 1210344-57-2 / MFCD21609259 / 436.890 / C22H25ClO7
TARGETMOL CHEMICALS INC ERTUGLIFLOZIN 100MG
Also available in 5 mg 10 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2). purity: 99%