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Ertugliflozin is a potent, selective, and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2). It has an IC50 of 0.877 nM for h-SGLT2 and demonstrates over 2000-fold selectivity for SGLT2 inhibition relative to SGLT1 in vitro. This compound has potential for the treatment of type 2 diabetes mellitus.
Potent and selective SGLT2 inhibitor
Orally active
Demonstrated concentration-dependent glucosuria in vivo
Potential for type 2 diabetes mellitus treatment
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Also available in 1 mg 10 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. (Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep. purity: 99%
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This antibody targets B7-H3 and exhibits anti-tumor activity. It can be utilized for the synthesis of antibody-drug conjugates (ADCs) and is suitable for research in areas such as small cell lung cancer, relapsed or refractory osteosarcoma, and advanced solid tumors.
Target: B7-H3
Exhibits anti-tumor activity
Can be studied for small cell lung cancer, relapsed or refractory osteosarcoma, and advanced solid tumors
Human IgG1 kappa isotype
Human species reactivity
Applications include ELISA, FACS, and functional assay
Unconjugated format
Can be reconstituted/diluted with sterile PBS or saline
Immobilized huB7H3-His can bind Risvutatug with an EC50 of 13.41 ng/mL
Purity: 99.57%
Molecular weight: 143.94 kDa
Appearance: liquid
Color: colorless to light yellow
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Also available in 1 mg, 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Blasticidin S HCl is a peptide-based nucleoside antibiotic (antibiotic) isolated from Streptomyces griseochromogenes that inhibits prokaryotic and eukaryotic protein synthesis by interfering with the formation of peptide bonds in the ribosome. Purity 98.67%
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10 MG; Eloralintide (LY 3841136) is an AMYR agonist, which is promising for research of type 2 diabetes and obesity. Purity: 99.84% (Synonyms: LY-3841136) CAS No. : 2883634-40-8
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