Furans
Medchemexpress LLC CX-6258 hydrochloride | 1353859-00-3 | MFCD28142834 | 99.0% | 498.40 | C26H25Cl2N3O3 | 10 MG
CX-6258 hydrochloride is the hydrochloride salt of a potent, kinase-selective pan-Pim inhibitor used for research applications. It exhibits low-nanomolar biochemical potency against Pim family kinases and is supplied with solubility and storage information to support in vitro and in vivo studies.
- Inhibits Pim-1, Pim-2, and Pim-3 with IC50s of 5 nM, 25 nM, and 16 nM, respectively.
- High purity (~99%) suitable for biochemical and cell-based assays.
- Available as a solid and as a 10 mM solution in DMSO for flexible use.
- Soluble in DMSO (10 mg/mL) and in water with heating (1 mg/mL).
- Storage recommendations provided for solid and solution to preserve stability.
- Orange to red solid facilitating visual inspection of material.
Medchemexpress LLC Fluticasone furoate | 397864-44-7 | C27H29F3O6S | 500 MG
Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. It exhibits potent anti-inflammatory and anti-asthmatic activity with low systemic exposure and has potential for treating allergic rhinitis.
- Potent anti-inflammatory and anti-asthmatic activity
- Low systemic exposure
- Potential for treating allergic rhinitis
- Available as a nasal spray for topical administration
- High potency in inhibiting tumor necrosis factor synthesis and action
- Effective in preventing damage to cultured human lung epithelial cells
Medchemexpress LLC Methyl 2-furoate | 611-13-2 | MFCD00003236 | 99.9% | 126.11 g·mol⁻1 | C6H6O3 | 100g
Methyl 2-furoate (Methyl furan-2-carboxylate) can be used to synthesize cis-fused 5-oxofuro[2 3-b]furans Methyl 2-furoate is also used in the preparation of sesquiterpene lactones[1]
eMolecules 123843-66-3 | Ambeed | 26-Difluoro-4-methoxybenzonitrile | 1g | 572827213 | A182524 | MFCD03094498 | 169.131 | C8H5F2NO
ChemScene | (S)-tert-Butyl (1-(3-chlorophenyl)-2-hydroxyethyl)carbamate | 1g | 572249035 | CS-0007846 | 1379546-46-9 | MFCD25541593 | 271.740 | C13H18ClNO3
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eMolecules 1020966-78-2 | 4-BROMOBENZOFURAN-3(2H)-ONE | MFCD09744091 | 1g
ChemScene | (S)-1-Methyl-26-dioxohexahydropyrimidine-4-carboxylic acid | 1g | 536849773 | CS-W006654 | 103365-69-1 | MFCD08460215 | 172.140 | C6H8N2O4
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Apexbio Technology LLC Mometasone furoate 83919-23-7 10mM (in 1mL DMSO)
Mometasone furoate (83919-23-7) is a glucocorticoid receptor agonist targeting intracellular glucocorticoid receptors It is designed to modulate glucocorticoid signaling pathways thereby regulating gene expression linked to inflammatory and allergic responses Mometasone furoate exerts its biological activity primarily through binding to cytoplasmic glucocorticoid receptors forming an activated complex that translocates into the nucleus and modulates target gene transcription This mechanism suppresses inflammatory cytokine production and inhibits inflammatory mediator release Based on these pharmacological properties Mometasone furoate holds research potential in experimental models of skin inflammatory disorders such as eczema and psoriasis as well as respiratory inflammatory processes including asthma
Medchemexpress LLC Mometasone furoate | 83919-23-7 | 99.86% | 521.43 | 500 MG
Mometasone furoate (Sch32088) is a glucocorticoid receptor agonist that demonstrates anti-inflammatory and anti-allergic properties. It functions as a corticosteroid agent, employed in topical applications for the management of chronic skin eczema and airway inflammation associated with asthma in living organisms.
- Functions as a glucocorticoid receptor agonist.
- Possesses anti-inflammatory activity.
- Exhibits anti-allergic activity.
- Acts as a corticosteroid.
- Suitable for topical applications.
- Aids in the management of chronic skin eczema.
- Contributes to the management of airway inflammation in asthma.
Cayman Chemical Mometason Furoate-d3 5mg
An internal standard for the quantification of mometasone furoate by GC- or LC-MS
Medchemexpress LLC Mometasone furoate impurity 1 | 1305334-30-8 | MFCD28359031 | 10mg
Mometasone furoate impurity 1 is an impurity of Mometasone furoate (HY-13693)
Medchemexpress LLC Mometasone furoate-13C,d6 | 83919-23-7 | 99.7% | 528.46 | 1 MG
Mometasone furoate-13C,d6 is a glucocorticoid receptor agonist with both anti-inflammatory and anti-allergic properties, acting as a corticosteroid agent. It is utilized for topical applications in chronic skin eczema and for managing airway inflammation in asthma. The compound functions by binding to glucocorticoid receptors, inducing conformational changes, and facilitating nuclear translocation.
- Glucocorticoid receptor agonist.
- Possesses anti-inflammatory and anti-allergic activity.
- Acts as a corticosteroid agent.
- Used for topical applications in chronic skin eczema.
- Used in management of airway inflammation in asthma in vivo.
- Inhibits LPS-stimulated nitrite production in J774 macrophages.
- More potent than Dexamethasone in inhibiting iNOS expression.
- Significantly inhibits cox-2 protein expression.
Medchemexpress LLC Methyl 2-furoate | 611-13-2 | MFCD00003236 | 99.9% | 126.11 g/mol | C6H6O3 | 250g
Methyl 2-furoate (Methyl furan-2-carboxylate) can be used to synthesize cis-fused 5-oxofuro[2 3-b]furans Methyl 2-furoate is also used in the preparation of sesquiterpene lactones[1]
eMolecules 13129-23-2 | Methyl furan-3-carboxylate | Combi-Blocks | MFCD06203671 | 126.111 | C6H6O3 | 98.000 | COC(=O)c1ccoc1 | 1g | 117534379
Methyl furan-3-carboxylate | Combi-Blocks | 13129-23-2 | MFCD06203671 | 126.111 | C6H6O3 | 98.000 | COC(=O)c1ccoc1 | 1g | 117534379
Medchemexpress LLC Mometasone furoate | 83919-23-7 | MFCD00866003 | 99.91% | 521.43 | 25 MG
Mometasone furoate (Standard) is an analytical standard primarily used for research and analytical applications. This glucocorticoid receptor agonist exhibits anti-inflammatory and anti-allergic activity, functioning as a corticosteroid agent for topical applications. It is commonly employed in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Glucocorticoid receptor agonist
- Exhibits anti-inflammatory and anti-allergic activity
- Functions as a corticosteroid agent
- Used for topical applications in chronic skin eczema and airway inflammation management of asthma in vivo
- Suitable for qualitative, quantitative, and methodological research experiments
- Compatible with techniques such as HPLC, GC, and MS
Medchemexpress LLC 2-furancarboxylic acid, methyl ester | 611-13-2 | MFCD00003236 | 99.9% | 126.11 g/mol | C6H6O3 | 1mL
Methyl 2-furoate (Methyl furan-2-carboxylate) can be used to synthesize cis-fused 5-oxofuro[2 3-b]furans Methyl 2-furoate is also used in the preparation of sesquiterpene lactones[1]