Imidazopyridines
Medchemexpress LLC Linaprazan glurate | 1228559-81-6 | 99.7% | C26H32N4O5 | 10MG
Linaprazan glurate is a small-molecule research compound that acts as a potassium-competitive acid blocker and is used in preclinical studies of gastric acid secretion and proton pump-related mechanisms. It is supplied as a high-purity solid for analytical, synthetic, and medicinal chemistry applications.
Medchemexpress LLC Az084 | 929300-19-6 | 99.7% | 5 MG
AZ084 is a selective, orally active CCR8 allosteric antagonist for research use. It demonstrates sub-nanomolar potency and is supplied as a high-purity solid suitable for in vitro and in vivo pharmacology studies. Solubility and storage guidance are provided to support experimental formulation and handling.
- Selective CCR8 allosteric antagonist with Ki ≈ 0.9 nM.
- High purity suitable for cellular and pharmacological assays.
- Supplied as a milligram-scale solid for in vitro and in vivo use.
- Highly soluble in DMSO; formulation examples provided for dosing.
- Recommended storage conditions for powder and solutions to preserve stability.
- Intended as a research tool for immunology and inflammation studies.
Medchemexpress LLC Bi-1622 | 2681392-19-6 | 99.0% | 508.53 g/mol | C26H24N10O2 | 10 MG
BI-1622 is an orally active, potent, and highly selective inhibitor of the HER2 (ERBB2) kinase, developed for preclinical research. It has reported biochemical potency (IC50) of 7 nM, shows greater than 25-fold selectivity over EGFR, and has demonstrated efficacy in HER2-driven xenograft models.
Medchemexpress LLC CXCR7 modulator 1 10mg | 2231812-31-8 | 10MG
CXCR7 modulator 1 (compound 25) is a potent and orally bioavailable peptoid hybrid CXCR7 modulator with a Ki of 9 nM[1
Medchemexpress LLC CXCR7 antagonist-1 | 1613021-99-0 | 99.9% | C21H19FN6O | 10MG
CXCR7 antagonist-1 is a research-grade small-molecule antagonist of the chemokine receptor CXCR7 (CAS 1613021-99-0). It inhibits binding of CXCL12/SDF-1 and CXCL11/I-TAC to CXCR7 and is supplied with high purity for in vitro and in vivo exploratory studies of tumor cell proliferation, migration, and inflammatory signaling.
- High purity suitable for biochemical and cellular assays.
- Known mechanism: blocks CXCL12 and CXCL11 binding to CXCR7.
- Available in multiple packaging sizes and solution formats.
- Recommended storage and handling information provided.
- Supplied for research use only.
![eMolecules 2072803-95-1 | OLPRINONE HYDROCHLORIDE HYDRATE | AstaTech | MFCD00946577 | 304.730 | C14H13ClN4O2 | 95.000 | O.Cl.Cc1[nH]c(=O)c(cc1-c1ccc2nccn2c1)C#N | 0.25g | 721754863](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502469485.JPG-250.jpg)
eMolecules 2072803-95-1 | OLPRINONE HYDROCHLORIDE HYDRATE | AstaTech | MFCD00946577 | 304.730 | C14H13ClN4O2 | 95.000 | O.Cl.Cc1[nH]c(=O)c(cc1-c1ccc2nccn2c1)C#N | 0.25g | 721754863
OLPRINONE HYDROCHLORIDE HYDRATE | AstaTech | 2072803-95-1 | MFCD00946577 | 304.730 | C14H13ClN4O2 | 95.000 | O.Cl.Cc1[nH]c(=O)c(cc1-c1ccc2nccn2c1)C#N | 0.25g | 721754863
Medchemexpress LLC (S)-3,5-dimethoxy-4-(4-(2-(1-methyl-1H-pyrazole-5-carboxamido)-3,3-diphenylpropanamido)phenyl) | 2748749-47-3 | 98.4% | C33H31N5O5 | 100 MG
IL-17A modulator-2 is a chemical compound identified by CAS number 2748749-47-3. It presents as a white to off-white solid with a high purity of 98.44% determined by HPLC. This compound has a molecular formula of C33H31N5O5 and a molecular weight of 577.63. It is recommended for research purposes only.
- Purity: 98.44% (HPLC)
- Appearance: White to off-white solid
- Molecular formula: C33H31N5O5
- Molecular weight: 577.63
- Storage: 4°C, sealed, away from moisture and light
- Storage in solvent: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture and light)
Medchemexpress LLC Linaprazan glurate (X842) | 1228559-81-6 | 99.65% | C26H32N4O5 | 50 MG
Linaprazan glurate (X842) is an orally active prodrug of Linaprazan. It provides a potent and prolonged inhibitory effect on gastric acid secretion by selectively inhibiting acid formation from gastric H⁺/K⁺-ATPase in a potassium-dependent manner. This compound is rapidly transformed by enzymatic cleavage into its active metabolite, linaprazan, and can be used for studies of erosive esophagitis (EE).
- Orally active prodrug
- Potent and prolonged inhibitory effect on gastric acid secretion
- Rapidly transformed into active metabolite, linaprazan
- Selectively inhibits acid formation from gastric H⁺/K⁺-ATPase
- Potassium-dependent mechanism
- Suitable for studies of erosive esophagitis (EE)
Medchemexpress LLC Linaprazan glurate | 1228559-81-6 | 99.7% | C26H32N4O5 | 100 MG
Linaprazan glurate (X842) is an orally active prodrug of Linaprazan that provides a potent and prolonged inhibitory effect on gastric acid secretion. It is rapidly transformed by enzymatic cleavage into its active metabolite, linaprazan. It acts as a potassium-competitive acid blocker, selectively inhibiting acid formation from gastric H⁺/K⁺-ATPase in a potassium-dependent manner. This product can be utilized for studies related to erosive esophagitis (EE).
- Orally active prodrug
- Potent and prolonged inhibitory effect on gastric acid secretion
- Rapidly transformed into active metabolite
- Potassium-competitive acid blocker
- Selectively inhibits acid formation from gastric H⁺/K⁺-ATPase
- Can be used for studies of erosive esophagitis (EE)
- Appearance: solid
- Color: white to off-white
Medchemexpress LLC HY-100412 5mg Medchemexpress, Linaprazan CAS:248919-64-4 Purity:>98%
Medchemexpress, HY-100412 5mg Linaprazan CAS:248919-64-4 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 261944-46-1 | Medchem Express | Soraprazan | 1mg | 446255407 | HY-100414 | MFCD21607984 | 367.449 | C21H25N3O3
AbaChemScene | 5-Chloroimidazo[12-a]pyridine | 250mg | 410748942 | CS-0038700 | 63111-79-5 | MFCD10698083 | 152.580 | C7H5ClN2
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Medchemexpress LLC PDE2A-IN-3 | 1426833-08-0 | 295.73 | 100 MG
PDE2A-IN-3 is a selective phosphodiesterase 2A (PDE2A) inhibitor with IC50s of 69 nM and 1762 nM for PDE2A and PDE10, respectively. It can be used for the study of neurological and psychiatric disorders.
- Selective phosphodiesterase 2A (PDE2A) inhibitor
- IC50 of 69 nM for PDE2A
- IC50 of 1762 nM for PDE10
- Suitable for studying neurological and psychiatric disorders
Medchemexpress LLC PDE2A-IN-3 | 1426833-08-0 | 295.73 | 50 MG
PDE2A-IN-3 (Example Ic1) is a selective phosphodiesterase 2A (PDE2A) inhibitor with IC50s of 69 nM and 1762 nM for PDE2A and PDE10, respectively. It can be used for the study of neurological and psychiatric disorders.
- Selective phosphodiesterase 2A (PDE2A) inhibitor
- IC50 of 69 nM for PDE2A and 1762 nM for PDE10
- Useful for research into neurological and psychiatric disorders
Medchemexpress LLC DGAT1-IN-3 | 939375-07-2 | 99.9% | 420.39 | 50 MG
DGAT1-IN-3 is a potent, selective and orally bioavailable inhibitor of DGAT-1, with IC50s of 38 nM for human DGAT-1 and 120 nM for rat DGAT-1. It could be used to research of obesity, dyslipidemia, and metabolic syndrome.
- IC50 of 38 nM for human DGAT-1; 120 nM for rat DGAT-1
- Inhibits human DGAT1 expressed in CHOK1 cells with an EC50 of 0.66 μM
- Blocks the human ether-a-go-go-related gene (hERG) encoded potassium channel with an IC20 of 0.2 μM
- Reduces weight gain and plasma triglycerides, and improves lipid profile (5-50 mg/kg; p.o once daily for three weeks)
- Exhibits good oral bioavailability (77%) and a maximum exposure level in plasma (Cmax) of 24 μM (50 mg/kg; p.o)
- Exhibits terminal elimination half-lives (1.95 h) and low clearance (13.5 mL/min/kg) (5 mg/kg; i.v)
eMolecules 106730-54-5 | Olprinone | MFCD25541649 | 1g
Pharmablock | 4-amino-23-difluorobenzonitrile | 25mg | 721310889 | PBTYC0222 | 112279-71-7 | MFCD09030642 | 154.120 | C7H4F2N2
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