Imidazopyrimidines
Medchemexpress LLC Xanthine oxidase, Microorganism | 9002-17-9 | ≥10 U/mg solid | 283 kDa | 100 U
Xanthine oxidase, Microorganism (XO) is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS). It catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid. This product is for research use only.
- Generates reactive oxygen species (ROS)
- Catalyzes oxidation of hypoxanthine to xanthine
- Catalyzes oxidation of xanthine to uric acid
- Rapidly and completely depletes hypoxanthine in human erythrocytes
- Inhibits growth of Plasmodium falciparum in human erythrocytes in vitro
- Reduces viability of postnatal cerebellar granule neurons
- Optimal pH is 7.5-8.0
- Soluble in water at 10 mg/mL or higher
Medchemexpress LLC BioE-1115 | 1268863-35-9 | 98.2% | 10 MG
BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. It also acts as a potent casein kinase 2α inhibitor with an IC50 of ~10 μM.
- Highly selective PASK inhibitor (IC50 ~4 nM).
- Potent casein kinase 2α inhibitor (IC50 ~10 μM).
- Induces dose-dependent loss of PASK phosphorylation in HEK293 cells.
- Reduces SREBP activity in HepG2 cells without affecting cell morphology or growth.
- Suppresses SREBP-1c target gene expression and SREBP-1 maturation in liver in vivo.
- Decreases insulin resistance, hepatic/serum triglycerides, and serum glucose dose-dependently.
- Does not cause significant changes in liver or body weight.
eMolecules 93778-15-5 | 2,3-dihydroxypropyl 4-hydroxybenzoate | Toronto Research Chemicals | MFCD21608153 | 212.201 | C10H12O5OCC(O)COC(=O)c1ccc(O)cc1 | 50mg | 601594345
2,3-dihydroxypropyl 4-hydroxybenzoate | Toronto Research Chemicals | 93778-15-5 | MFCD21608153 | 212.201 | C10H12O5OCC(O)COC(=O)c1ccc(O)cc1 | 50mg | 601594345
eMolecules 58-08-2 | Caffeine | Chem-Impex | MFCD00005758 | 194.194 | C8H10N4O2 | 99.000 | Cn1cnc2n(C)c(=O)n(C)c(=O)c12 | 250g | 490848234
Caffeine | Chem-Impex | 58-08-2 | MFCD00005758 | 194.194 | C8H10N4O2 | 99.000 | Cn1cnc2n(C)c(=O)n(C)c(=O)c12 | 250g | 490848234
Medchemexpress LLC HY-B1505 100mg Medchemexpress, Acefylline CAS:652-37-9 Purity:>98%
Medchemexpress, HY-B1505 100mg Acefylline CAS:652-37-9 Acefylline is an adenosine receptor antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC XAC 96865-92-8 5mg
XAC is a small-molecule antagonist targeting adenosine receptors It is designed to competitively inhibit the binding of adenosine to its receptors thereby modulating receptor-mediated signaling pathways XAC exerts its biological activity primarily through interference with adenosine-induced signaling Experimental studies indicate that XAC inhibits adenosine-induced cellular processes such as neurotransmission modulation and cardiovascular responses Based on these pharmacological properties XAC holds research potential in neuroscience and cardiovascular physiology to investigate adenosine-mediated signaling pathways in specific cellular events and physiological conditions
U.S. Pharmacopeia Caffeine, 58-08-2, MFCD00005758, 200mg
Molecular formula C8H10N4O2, Molecular weight 194.19, Melting Point 455 - 462.2 °F (235 - 239 °C), Boiling Point 352.4 °F (178 °C) (sublimes), Synonyms: 1,3,7-Trimethylxanthine
TARGETMOL CHEMICALS INC XANTHINE OXIDASE-IN-1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Xanthine oxidase-IN-1 is a useful organic compound for research related to life sciences. The catalog number is T10509 and the CAS number is 1071970-13-2. purity: 99%
TARGETMOL CHEMICALS INC XANTHINE OXIDOREDUCTASE- 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor (IC50 26.3 nM).Xanthine oxidoreductase-IN-3 can be used in acute hyperuricemia studies. purity: 98%
Selleck Chemical LLC 3-Methylxanthine
3-Methylxanthine (3-MX) a 3-alkylxanthine is an inhibitor of cyclic guanosine monophosphate (GMP) phosphodiesterase (PDE) with IC50 of 920 M on guinea-pig isolated trachealis muscle
Medchemexpress LLC Racemic lisofylline | 6493-06-7 | MFCD00871850 | 98.6% | 280.33 g/mol | C13H20N4O3 | 50MG
Racemic lisofylline is the racemate of lisofylline, an anti-inflammatory research compound and a metabolite-derived analogue of pentoxifylline. It is used in biochemical and cellular studies for its inhibition of phosphatidic acid and free fatty acid generation, and is supplied as a high-purity solid for research applications.
- Purity 98.6%.
- Molecular weight 280.33 g/mol.
- Molecular formula C13H20N4O3.
- Available in small quantities including 50 mg.
- Used in studies of inflammation and oxidative tissue injury.
- Supplied as a solid powder for biochemical assays.
Chem-Impex International, Inc. Xanthine | 69-89-6 | MFCD00078453 | 5G
Xanthine, 69-89-6, MFCD00078453, 5G
Chemscene ChemScene | 8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione | 10G | CS-W019625 | 0.98 | 93703-24-3| MFCD00462528 | 245.03
ChemScene | 8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione | 10G | CS-W019625 | 0.98 | 93703-24-3| MFCD00462528 | 245.03
Medchemexpress LLC 3-Methylxanthine | 1076-22-8 | 99.5% | C6H6N4O2 | 10 G
3-Methylxanthine is a xanthine derivative and a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle. It is a laboratory chemical primarily used for research and the manufacture of substances.
- Appears as a solid
- Color ranges from white to khaki
- Endogenous metabolite
- Soluble in 1M NaOH (50 mg/mL)
- Soluble in DMSO (2 mg/mL)
- Insoluble in water
- For research use only
Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 100.0% | 222.24 | C10H14N4O2 | 25MG
IBMX (3-Isobutyl-1-methylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor used as a research reagent to elevate intracellular cyclic nucleotides by inhibiting multiple PDE isoforms. It is supplied as a stable solid with documented physicochemical, purity, and solubility data for preparation of in vitro and in vivo formulations.
- Broad-spectrum PDE inhibitor with reported IC50s of 6.5 μM (PDE3), 26.3 μM (PDE4), and 31.7 μM (PDE5).
- Molecular formula C10H14N4O2; molecular weight 222.24 g/mol.
- High purity suitable for research (reported purities ~99.97-99.99%).
- Soluble in DMSO (125 mg/mL) and compatible with published in vivo cosolvent formulations.
- Available in multiple solid pack sizes, including 25 MG, for assay preparation.
- Recommended storage: powder -20°C (short term refrigerated at 4°C), in solvent -80°C for long term.