Imidazopyrimidines
TARGETMOL CHEMICALS INC IBMX 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 uM). IBMX enhances the intracellular cAMP level. Purity 99.8%
Selleck Chemical LLC Mercaptopurine (6-MP) S1305-1g
Mercaptopurine(6-MP) is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA
eMolecules Medchem Express / FAPy-adenine / 10mg / 552386474 / HY-113303 / / 5122-36-1 / MFCD00047382 / 153.145 / C5H7N5O
Medchem Express / FAPy-adenine / 10mg / 552386474 / HY-113303 / / 5122-36-1 / MFCD00047382 / 153.145 / C5H7N5O
Medchemexpress LLC 6-mercaptopurine hydrate | 6112-76-1 | MFCD03854445 | 99.9% | 170.19 g/mol | C5H6N4OS | 5 MG
6-mercaptopurine hydrate is the hydrated form of the purine analogue 6-mercaptopurine, used in research as an inhibitor of purine metabolism and as a reference compound in biochemical and pharmacological assays.
- Hydrated purine analogue; CAS 6112-76-1.
- Molecular formula C5H6N4OS and molecular weight 170.19 g/mol.
- High purity (99.9% by HPLC) suitable for analytical use.
- Solid monohydrate form with consistent batch characterization.
- Commonly used in in vitro and in vivo pharmacology and biochemical assays.
- Supplied in small research pack sizes for laboratory applications.
Research Products International Corp Adenine USP 500 G
A nucleobase with a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate and the cofactors nicotinamide adenine dicucleotide and flavin adenine dinucleotide, and protein synthesis, as a chemical component of DNA and RNA.
Selleck Chemical LLC Mercaptopurine (6-MP) S1305-10mM/1mL
Mercaptopurine(6-MP) is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA
Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 100.0% | 222.24 g/mol | C10H14N4O2 | 500MG
IBMX (3-isobutyl-1-methylxanthine) is a non-selective phosphodiesterase (PDE) inhibitor supplied as an analytical standard for research use. It increases intracellular cAMP and cGMP by inhibiting multiple PDE isoforms and is provided as a high-purity solid for laboratory applications. Reported IC50 values include 6.5 μM (PDE3), 26.3 μM (PDE4), and 31.7 μM (PDE5).
- Non-selective phosphodiesterase inhibitor.
- Modulates intracellular cAMP and cGMP levels.
- Useful for biochemical assays and cell-based studies.
- Provided as a high-purity analytical standard for research.
- Reported IC50s: PDE3 6.5 μM, PDE4 26.3 μM, PDE5 31.7 μM.
Selleck Chemical LLC Theobromine S2368-50mg
Theobromine (3 7-Dimethylxanthine) is a xanthine alkaloid widely consumed as stimulants and snacks in coffee and cocoa based foods and most often as part of ingredients in drugs
Medchemexpress LLC Adenine monohydrochloride hemihydrate | 6055-72-7 | MFCD11046306 | 99.9% | 189.60 | C5H8ClN5O | 1 ML
Adenine monohydrochloride hemihydrate is the hydrochloride salt (hemihydrate) of adenine, supplied as a solid or as a pre-made 10 mM solution in DMSO. It is used as a biochemical reagent and nucleobase source in molecular biology and biochemical assays, and is provided with supporting analytical documentation for quality control.
- High purity (99.87%) for reliable analytical results.
- Available as solid and 10 mM solution in DMSO for experimental flexibility.
- White to off-white solid, easy to handle and store.
- Supplied with COA, SDS, HPLC, and MS documentation for verification.
- Store at 4°C and protect from light; solutions: -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC (R)-lisofylline | 100324-81-0 | MFCD00867573 | 100.0% | 280.32 g/mol | C13H20N4O3 | 5 MG
(R)-Lisofylline is the R-enantiomer of lisofylline, a metabolite of pentoxifylline with documented anti-inflammatory activity. It is used as a research compound to probe lipid signaling and immune pathways, including inhibition of lysophosphatidic acid acyltransferase and disruption of IL-12-mediated STAT4 activation.
- R-enantiomer of lisofylline.
- Lysophosphatidic acid acyltransferase inhibitor (reported IC50 ≈ 0.6 μM).
- Modulates IL-12-STAT4 signaling relevant to immunology research.
- Provided in small milligram research packs for laboratory use.
- Store under nitrogen at -20°C; in solvent, -80°C for up to 6 months.
- Molecular weight 280.32 g/mol; formula C13H20N4O3.
Medchemexpress LLC 6H-Purine-6-thione, 1,2,3,9-tetrahydro-, hydrate (1:1) | 6112-76-1 | 99.9% | 170.19 | 500 MG
6-Mercaptopurine hydrate is a purine analogue that acts as an antagonist of endogenous purines. It has been widely used as an antileukemic agent and immunosuppressive agent.
- Induces NR4A3 transcriptional activity.
- Increases NR4A3 protein levels.
- Increases cell surface GLUT4 in basal and insulin-stimulated cells.
- Increases phospho-AS160.
- Significantly inhibits EcSTH-induced phosphorylation of AMPK and ACC1.
- Promotes an increase in S phase cell population in fetal telencephalons.
- Promotes an increase in G2/M phase cell population in fetal telencephalons.
- Increases sub-G1 phase cell population (apoptotic cells).
- Inhibited expression of CAV1 protein in MM1S cells.
- Further promoted bortezomib-mediated survival of MM-bearing mice.
Chem-Impex International, Inc. Caffeine, anhydrous | 58-08-2 | MFCD00005758 | 1KG
Caffeine, anhydrous, 58-08-2, MFCD00005758, 1KG
Sigma Aldrich Fine Chemicals Biosciences 3-Isobutyl-1-methylxanthine 99 (HPLC), powder, 28822-58-4, MFCD00005584
3-Isobutyl-1-methylxanthine 99 (HPLC), powder
Matrix Scientific 3-METHYL-1H-PURINE-2,6(3H,7H-5
3-methyl-1h-purine-2,6(3h,7h)-dione Mf C6h6n4o2 Mw 166.14 Cas 1076-22-8 Mdl MFCD00005580
Chem-Impex International, Inc. Uric acid | 69-93-2 | MFCD00005712 | 25G
Uric acid, 69-93-2, MFCD00005712, 25G