Imidazopyrimidines
Medchemexpress LLC Theophylline (Standard) | 58-55-9 | 99.99% | 25 MG
Theophylline (Standard) is an analytical standard, also known as 1,3-Dimethylxanthine. This potent phosphodiesterase (PDE) inhibitor and adenosine receptor antagonist is intended for research and analytical applications. It is commonly used as a reference standard for assay in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for research and analysis
- Inhibits PDE3 activity
- Acts as an adenosine receptor antagonist
- Increases IL-10 for anti-inflammatory effects
- Induces apoptosis
Apexbio Technology LLC IBMX(Synonyms: 3-Isobutyl-1-methylxanthine, 1-Methyl-3-isobutylxanthine, 3-Isobutyl-1-methyl-xanthine), 50mg, CAS: 28822-58-4.
IBMX (CAS 28822-58-4) is a methylxanthine derivative commonly employed in research as a non-selective inhibitor of phosphodiesterase (PDE) isozymes It inhibits PDE3 PDE4 and PDE5 with IC50 values of approximately 6 5 26 3 and 31 7 M respectively By inhibiting PDE activity IBMX elevates intracellular cyclic AMP (cAMP) and cyclic GMP (cGMP) concentrations thereby activating downstream cyclic nucleotide-dependent protein kinases Additionally IBMX antagonizes adenosine receptors blocking endogenous adenosine-mediated cellular effects In animal studies IBMX administration has been shown to modulate drug-induced behavioral sensitization highlighting its utility in neuropharmacological research
Medchemexpress LLC Xanthine | 69-89-6 | MFCD00078453 | 100.0% | 152.11 g/mol | C5H4N4O2 | 10 G
Xanthine is a purine alkaloid and endogenous metabolite used as a research reagent and reference standard. It functions as an intermediate in purine degradation and is used in biochemical and metabolic studies, analytical method development, and assay validation. Supplied as a powdered solid with defined molecular properties suitable for laboratory use.
- Purine alkaloid and endogenous metabolite suitable for research.
- Useful as a reference standard in analytical and metabolic assays.
- Stable powdered form for ease of handling and storage.
- Available in multiple pack sizes to support small- and large-scale experiments.
- Characterized molecular formula C5H4N4O2 and molecular weight 152.11 g/mol.
- High purity suitable for biochemical applications.
Sigma Aldrich Fine Chemicals Biosciences 3-Isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 250 mg
3-Isobutyl-1-methylxanthine | Purity: ≥99% | Mol Wt: 222.24 | 28822-58-4 | MFCD00005584 | 250 mg
Medchemexpress LLC Theophylline (Standard) | 58-55-9 | 99.99% | 50 MG
Theophylline (Standard) is the analytical standard of Theophylline. It is intended for research and analytical applications. It inhibits PDE3 activity to relax airway smooth muscle, has anti-inflammatory activity by increasing IL-10 and inhibiting NF-κB into the nucleus, and induces apoptosis.
- Potent phosphodiesterase (PDE) inhibitor
- Adenosine receptor antagonist
- Histone deacetylase (HDAC) activator
- Induces apoptosis
- Used for asthma and chronic obstructive pulmonary disease (COPD) research
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Selleck Chemical LLC IBMX
IBMX (Isobutylmethylxanthine 1-Methyl-3-Isobutylxanthine) is a nonspecific inhibitor of phosphodiesterase (PDE) with IC50 values of 6 5 1 2 26 3 3 9 and 31 7 5 3 M for PDE3 4 and 5 respectively It may enhance the intracellular cAMP levels and also acts as an adenosine (A1) receptor antagonist
Sigma Aldrich Fine Chemicals Biosciences Caffeine powder ReagentPlu500G
Caffeine is a widely ingested pharmacologically active substance. It belongs to the class of methylxanthines. It is a naturally occurring alkaloid found in coffee cocoa and other plants. Caffeine might be associated with osteoporosis cardiovascular risk arrhythmia and gastrointestinal disturbances. Caffeine is used to treat orthostatic hypotension bronchopulmonary dysplasia and apnea of prematurity (AOP).
eMolecules 6493-06-7 | Medchem Express | ()-Lisofylline | 5mg | 721309414 | HY-126042 | MFCD00871850 | 280.328 | C13H20N4O3
Medchem Express | ()-Lisofylline | 5mg | 721309414 | HY-126042 | 6493-06-7 | MFCD00871850 | 280.328 | C13H20N4O3
Sigma Aldrich Fine Chemicals Biosciences 3-Isobutyl-1-methylxanthine 99 (HPLC), powder, 28822-58-4, MFCD00005584
3-Isobutyl-1-methylxanthine 99 (HPLC), powder
Medchemexpress LLC Xanthine | 69-89-6 | MFCD00078453 | 100.0% | 152.11 g/mol | C5H4N4O2 | 50 G
Xanthine is a purine base and endogenous metabolite used as a biochemical reagent and reference in research. It participates in purine catabolism and is applied in enzymology, metabolic studies, and analytical assays. The compound is typically supplied as a dry powder that requires appropriate storage and handling per supplier guidance.
- Purine base and endogenous metabolite used in biochemical research.
- Suitable for enzymatic assays and metabolic pathway studies.
- Soluble in alkaline aqueous solutions and moderately soluble in water with heating.
- Stable as a powder when stored refrigerated or frozen following datasheet recommendations.
- Offered in multiple package sizes to support small-scale and preparative use.
Medchemexpress LLC (R)-Lisofylline | 100324-81-0 | 99.99% | 280.32 | 1 G
(R)-Lisofylline | 100324-81-0 | 99.99% | 280.32 | 1 G
Medchemexpress LLC (R)-Lisofylline | 100324-81-0 | 99.99% | 280.32 | 1 ML
(R)-Lisofylline is the (R)-enantiomer of a Pentoxifylline metabolite with anti-inflammatory properties. It acts as a lysophosphatidic acid acyltransferase inhibitor with an IC50 of 0.6 μM and disrupts IL-12 signaling-mediated STAT4 activation. It has potential for research in type 1 diabetes and autoimmune disorders.
- Acts as a lysophosphatidic acid acyltransferase inhibitor.
- Interrupts IL-12 signaling-mediated STAT4 activation.
- Blocks IL-12-driven Th1 differentiation and T cell proliferation.
- Reduces impairment of insulin secretion induced by IL-1β.
- Suppresses IFN-γ production and onset of diabetes in NOD mice.
- Ameliorates experimental allergic encephalomyelitis in mice.
- Improves survival in mice injected with a lethal dose of LPS.
- Ameliorates sepsis-induced lung injury in minipigs.
![Revvity Health Sciences Inc Caffeine, [1-Methyl-<sup>14</sup>C]-, 50µCi (1.85MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502812312.jpg-250.jpg)
Revvity Health Sciences Inc Caffeine, [1-Methyl-14C]-, 50µCi (1.85MBq)
Caffeine, [1-Methyl-14C]-, 50µCi (1.85MBq)
TARGETMOL CHEMICALS INC 7-Methylxanthine 50MG
Also available in 1 mL, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. 7-Methylxanthine is a methyl derivative of xanthine, the purine component of human urinary calculi.7-Methylxanthine has an affinity for adenosine receptors.7-Methylxanthine is a methyl derivative of xanthine, the purine component of human urinary calculi.7-Methylxanthine has an affinity for adenosine receptors. Purity 98.58%
eMolecules 58-08-2 | Caffeine | Chem-Impex | MFCD00005758 | 194.194 | C8H10N4O2 | 99.000 | Cn1cnc2n(C)c(=O)n(C)c(=O)c12 | 5kg | 490848237
Caffeine | Chem-Impex | 58-08-2 | MFCD00005758 | 194.194 | C8H10N4O2 | 99.000 | Cn1cnc2n(C)c(=O)n(C)c(=O)c12 | 5kg | 490848237