Imidazopyrimidines
Apexbio Technology LLC IBMX(Synonyms: 3-Isobutyl-1-methylxanthine, 1-Methyl-3-isobutylxanthine, 3-Isobutyl-1-methyl-xanthine), 50mg, CAS: 28822-58-4.
IBMX (CAS 28822-58-4) is a methylxanthine derivative commonly employed in research as a non-selective inhibitor of phosphodiesterase (PDE) isozymes It inhibits PDE3 PDE4 and PDE5 with IC50 values of approximately 6 5 26 3 and 31 7 M respectively By inhibiting PDE activity IBMX elevates intracellular cyclic AMP (cAMP) and cyclic GMP (cGMP) concentrations thereby activating downstream cyclic nucleotide-dependent protein kinases Additionally IBMX antagonizes adenosine receptors blocking endogenous adenosine-mediated cellular effects In animal studies IBMX administration has been shown to modulate drug-induced behavioral sensitization highlighting its utility in neuropharmacological research
Sigma Aldrich Fine Chemicals Biosciences THEOPHYLLINE ANHYDROUS, 99%,
Theophylline anhydrous, ≥99%, powder
Sigma Aldrich Fine Chemicals Biosciences Nicotinic acid adenine din25MG
Nicotinic acid adenine dinucleotide (deamido-NAD NAAD) is a closely related analog of NAD. It is used to study the structure of nicotinate mononucleotide adenylyltransferase(s) (NMN/NaMN). NAAD is used as a substrate to study the specificity and kinetics of nicotinamide adenine dinucleotide synthetase(s) (NADS). In addition it is also used as a co-substrate to study mechanisms of members of the Sir2 class of NAD-dependent deacetylase.
Sigma Aldrich Fine Chemicals Biosciences Xanthine 9910G
Xanthine is synthesized from guanine in the presence of guanine deaminase. Xanthine oxidase catalyzes the production of xanthine from hypoxanthine and its subsequent breakdown to uric acid. Xanthine derivatives are present in coffee tea and cocoa seeds. Xanthine has been proposed as a lead for the generation of pharmacologically active compounds.
![eMolecules 35920-39-9 | NECA | Tocris Bioscience (Bio-Techne US) | MFCD00069195 | 308.298 | C12H16N6O4 | 98.000 | CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 | 50mg | 389985236](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1709110.jpg-250.jpg)
eMolecules 35920-39-9 | NECA | Tocris Bioscience (Bio-Techne US) | MFCD00069195 | 308.298 | C12H16N6O4 | 98.000 | CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 | 50mg | 389985236
NECA | Tocris Bioscience (Bio-Techne US) | 35920-39-9 | MFCD00069195 | 308.298 | C12H16N6O4 | 98.000 | CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 | 50mg | 389985236
Caffeine (Powder/USP/FCC), Fisher Chemical
CAS: 58-08-2 Molecular Formula: C8H10N4O2 Molecular Weight (g/mol): 194.19 MDL Number: MFCD00005758 InChI Key: RYYVLZVUVIJVGH-UHFFFAOYSA-N Synonym: caffeine,1,3,7-trimethylxanthine,guaranine,thein,cafeina,methyltheobromine,koffein,mateina,theine,alert-pep PubChem CID: 2519 ChEBI: CHEBI:27732 IUPAC Name: 1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione SMILES: CN1C=NC2=C1C(=O)N(C)C(=O)N2C
7-Methyladenine 98%, Thermo Scientific™
CAS: 935-69-3 Molecular Formula: C6H7N5 Molecular Weight (g/mol): 149.157 InChI Key: HCGHYQLFMPXSDU-UHFFFAOYSA-N Synonym: 7-methyladenine,7-methyl-7h-purin-6-amine,6-amino-7-methylpurine,n7-methyladenine,adenine, 7-methyl,7h-purin-6-amine, 7-methyl,7h-purin-6-amine, 7-methyl-9ci,7-methyl-7h-adenine,7-methyl-6-purinamine PubChem CID: 71593 ChEBI: CHEBI:28921 IUPAC Name: 7-methylpurin-6-amine SMILES: CN1C=NC2=C1C(=NC=N2)N
Pentoxifylline, Thermo Scientific™
CAS: 5-6-6493 Molecular Formula: C13H18N4O3 Molecular Weight (g/mol): 278.31 InChI Key: BYPFEZZEUUWMEJ-UHFFFAOYSA-N Synonym: pentoxifylline,trental,oxpentifylline,pentoxifyllin,torental,pentoxyphylline,pentoxil,dimethyloxohexylxanthine,pentoxiphyllium,vazofirin PubChem CID: 4740 ChEBI: CHEBI:7986 IUPAC Name: 3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione SMILES: CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C
3-Methylxanthine, 97%, Thermo Scientific™
CAS: 1076-22-8 Molecular Formula: C6H6N4O2 Molecular Weight (g/mol): 166.14 InChI Key: GMSNIKWWOQHZGF-UHFFFAOYSA-N Synonym: 3-methylxanthine,3-methyl-1h-purine-2,6 3h,7h-dione,2,6-dihydroxy-3-methylpurine,xanthine, 3-methyl,3 mx,3-methyl xanthine,1h-purine-2,6-dione, 3,7-dihydro-3-methyl,unii-ws6x982oec,3-methyl-2,3,6,7-tetrahydro-1h-purine-2,6-dione,ccris 5817 PubChem CID: 70639 ChEBI: CHEBI:62207 IUPAC Name: 3-methyl-7H-purine-2,6-dione SMILES: CN1C2=C(C(=O)NC1=O)NC=N2
2'-Deoxyadenosine-5'-triphosphate disodium salt, 98%, Thermo Scientific™
CAS: 74299-50-6 Molecular Formula: C10H14N5Na2O12P3 Molecular Weight (g/mol): 535.15 MDL Number: MFCD00080335 InChI Key: JEKDCIBJADJZSK-DZVPOJRENA-L Synonym: 2'-deoxyadenosine-5'-triphosphate disodium salt PubChem CID: 131674273 IUPAC Name: disodium;[[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate SMILES: [Na+].[Na+].NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O3)C2=NC=N1
Theophylline monohydrate, 99%
CAS: 5967-84-0 Molecular Formula: C7H10N4O3 Molecular Weight (g/mol): 198.182 MDL Number: MFCD00151659 InChI Key: INQSMEFCAIHTJG-UHFFFAOYSA-N Synonym: theophylline monohydrate,quibron,quibron plus,theo-sav,dimethylxanthine,aerolate jr,theoclear-100,unii-c137dtr5rg,c7h8n4o2.h2o,theoclear l.a.-260 PubChem CID: 91268 IUPAC Name: 1,3-dimethyl-7H-purine-2,6-dione;hydrate SMILES: CN1C2=C(C(=O)N(C1=O)C)NC=N2.O
Theophylline-7-acetic acid, 98%, Thermo Scientific Chemicals
CAS: 652-37-9 Molecular Formula: C9H9N4NaO4 Molecular Weight (g/mol): 260.19 MDL Number: MFCD00022832 InChI Key: MSFVZSOKOXZSME-UHFFFAOYSA-M Synonym: acefylline,theophylline-7-acetic acid,acephylline,theophyllineacetic acid,carboxymethyltheophylline,7-carboxymethyl theophylline,7-theophyllinylacetic acid,theophyllin-7-ylacetic acid,7-theophyllinessigsaeure,7-theophyllineacetic acid PubChem CID: 69550 IUPAC Name: 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetic acid SMILES: [Na+].CN1C2=C(N(CC([O-])=O)C=N2)C(=O)N(C)C1=O