Lactams
Selleck Chemical LLC Sulbactam S1958-10mg
Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0 8 M
Selleck Chemical LLC Tazobactam S3077-100mg
Tazobactam (Tazobactam acid Tazobactamum) is a -lactamases Inhibitor with antibacterial activity It also inhibits the class D oxacillinase OXA-2 It is used in combination with piperacillin and other -lactam antibiotics to broaden their spectrum and enhance their effect
eMolecules AstaTech / (S)-3-((TERT-BUTYLDIMETHYLSILYL)OXY)PYRROLIDIN-2-ONE / 0.25g / 296387864 / W11603 / 95.000 / 130403-91-7 / MFCD26394938 / 215.368 / C10H21NO2Si
AstaTech / (S)-3-((TERT-BUTYLDIMETHYLSILYL)OXY)PYRROLIDIN-2-ONE / 0.25g / 296387864 / W11603 / 95.000 / 130403-91-7 / MFCD26394938 / 215.368 / C10H21NO2Si
![eMolecules 2-[3-[tert-Butyl(dimethyl)silyl]oxypropoxy]acetonitrile | 1430412-80-8 | | 500mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502168186.JPG-250.jpg)
eMolecules 2-[3-[tert-Butyl(dimethyl)silyl]oxypropoxy]acetonitrile | 1430412-80-8 | | 500mg
Synthonix - Stock | 2-[3-[tert-Butyl(dimethyl)silyl]oxypropoxy]acetonitrile | 500mg | 525932268 | T10078 | | 1430412-80-8 | | 229.395 | C11H23NO2Si
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Apexbio Technology LLC Tazobactam (sodium salt) 89785-84-2 250mg
Tazobactam sodium salt (CAS 89785-84-2) is a small-molecule inhibitor targeting -lactamases It is designed to irreversibly bind to -lactamases thereby preventing the enzyme-mediated hydrolysis of -lactam antibiotics Tazobactam sodium salt exerts its biological activity primarily through -lactamase inhibition In microbiological assays tazobactam demonstrates intrinsic antibacterial activity against several Acinetobacter strains typically with MIC values of 8 mg/L (range 2 32 mg/L) Based on these pharmacological properties tazobactam sodium salt holds research potential in microbiological assessments and efficacy evaluations of -lactam antibiotic combinations
![eMolecules Medchem Express / Sulbactam / 100mg / 446272524 / HY-B0334 / / 68373-14-8 / [null] / 233.240 / C8H11NO5S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502445100.PNG-250.jpg)
eMolecules Medchem Express / Sulbactam / 100mg / 446272524 / HY-B0334 / / 68373-14-8 / [null] / 233.240 / C8H11NO5S
Medchem Express / Sulbactam / 100mg / 446272524 / HY-B0334 / / 68373-14-8 / [null] / 233.240 / C8H11NO5S
Medchemexpress LLC Sulbactam pivoxil | 69388-79-0 | MFCD00867003 | 98.0% | 347.38 | C14H21NO7S | 100 MG
Sulbactam pivoxil is the pivoxil ester prodrug of sulbactam, a β-lactamase inhibitor supplied as a research/analytical standard. The material is provided as a white to off-white solid with reported purity of 98.0% and a molecular weight of 347.38, and is used to support studies of oral bioavailability, pharmacokinetics, and β-lactamase inhibition.
- Prodrug form improves oral absorption compared with sulbactam.
- Useful as a reference standard for pharmacokinetic and microbiology studies.
- High reported purity supports analytical and formulation work.
- Available in solid and ready-to-use solution formats for flexibility.
- Recommended storage conditions provided to preserve stability.
Medchemexpress LLC Aztreonam | 78110-38-0 | MFCD00072145 | 99.6% | 435.43 | C13H17N5O8S2 | 10 MG
Aztreonam (standard) is an analytical reference material containing the monobactam antibiotic aztreonam. Provided at high purity, it is intended for analytical testing, assay calibration, method validation, and quality control in pharmaceutical and biochemical laboratories.
- Analytical reference standard for aztreonam.
- High purity suitable for assay and quality control work.
- Available in small precision pack sizes for analytical use.
- Reported molecular weight 435.43 and formula C13H17N5O8S2.
- Includes CAS number 78110-38-0 for unambiguous identification.
eMolecules Synthonix 4-Acetoxy-2-azetidinone 250mg 779536178 A15221 0 000 28562-53-0 MFCD00010593 129 115 C5H7NO3
Synthonix 4-Acetoxy-2-azetidinone 250mg 779536178 A15221 0 000 28562-53-0 MFCD00010593 129 115 C5H7NO3
Apexbio Technology LLC Sulbactam sodium 69388-84-7 10mM (in 1mL H2O)
Sulbactam sodium is a competitive and irreversible inhibitor targeting -lactamase enzymes It functions predominantly through binding the active site of -lactamases thereby obstructing these enzymes from hydrolyzing -lactam antibiotics Widely employed in biomedical research Sulbactam sodium is utilized for evaluating bacterial resistance mechanisms characterizing susceptibility profiles of -lactamase-expressing clinical isolates and examining synergistic therapeutic combinations Moreover Sulbactam sodium itself exhibits antimicrobial activity notably against Acinetobacter species clinically resistant to common antibiotics In antibacterial assays against certain -lactamase-producing bacterial strains Sulbactam sodium typically demonstrates inhibitory effects at IC50 values ranging approximately from 5 to 25 g/mL depending upon specific experimental conditions
Medchemexpress LLC Thalidomide-O-amido-C4-NH2 (trifluoroacetate) | 1799711-25-3 | MFCD31560484 | 99.9% | 516.42 g/mol | C21H23F3N4O8 | 50 MG
Thalidomide-O-amido-C4-NH2 (trifluoroacetate) is a thalidomide-derived cereblon ligand supplied as the TFA salt for use as an E3 ligase ligand/linker building block in PROTAC and chemical biology research.
- Provided as the trifluoroacetate salt.
- High purity (99.9%, LCMS).
- Molecular weight 516.42 g/mol.
- CAS number 1799711-25-3.
- Appearance: solid, white to off-white.
- Packaged as a 50 MG quantity.
Medchemexpress LLC Thalidomide-O-COOH | 1061605-21-7 | MFCD31560477 | >98.0% | 332.27 | C15H12N2O7 | 10 G
Thalidomide-O-COOH is a thalidomide-derived cereblon (CRBN) ligand used as an E3 ligase recruiting moiety in PROTAC and targeted protein degradation design. The compound is supplied as a solid with molecular formula C15H12N2O7 and molecular weight 332.27 g/mol (CAS 1061605-21-7).
- Serves as a cereblon (CRBN) binding ligand for PROTAC construction.
- Suitable for medicinal chemistry and chemical biology research.
- Provided in multiple laboratory-scale pack sizes for synthesis and screening.
- Characterized by manufacturer datasheet and SDS for handling and storage guidance.
Medchemexpress LLC Thalidomide-5-peg2-cl | 2230956-57-5 | 96.6% | C17H17ClN2O6 | 10MG
Thalidomide-5-PEG2-Cl is a thalidomide-derived cereblon (CRBN) ligand featuring a short PEG2 spacer and a terminal chloride. It is supplied as a research-grade building block for conjugation in PROTAC design and other CRBN-targeting chemical biology applications, with documented molecular formula and purity.
- Provides a CRBN-recruiting moiety suitable for PROTAC assembly.
- Contains a PEG2 linker for flexible conjugation to ligands.
- Terminal chloride enables straightforward chemical derivatization.
- Supplied with referenced purity and characterization data.
- Available in small research-friendly pack sizes for early-stage work.
Medchemexpress LLC Tetrazine-tagged thalidomide | 2087490-42-2 | 98.6% | 571.58 g/mol | C29H29N7O6 | 100 MG
Tz-Thalidomide is a tetrazine-tagged derivative of thalidomide used in bioorthogonal click-chemistry and as an E3 ligase ligand for biochemical research. It contains a reactive tetrazine group for rapid conjugation via inverse electron demand Diels-Alder reactions and has been characterized for binding to BRD4.
- Tetrazine moiety enables rapid inverse electron demand Diels-Alder (iEDDA) click reactions.
- Functions as an E3 ligase ligand for targeted protein interaction studies.
- Documented binding affinity to BRD4 in biochemical assays.
- High purity suitable for research applications.
- Available as a solid and as a 10 mM solution in DMSO for experimental flexibility.