Lactams
Medchemexpress LLC Thalidomide-NH-C9-NH2 hydrochloride | 2305936-77-8 | 99.9% | 450.96 g/mol | C22H31ClN4O4 | 10 MG
Thalidomide-NH-C9-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied as a hydrochloride salt for use in proteolysis-targeting chimera (PROTAC) construction and related chemical biology research. Provided as a light yellow solid with high purity and defined storage stability, it is intended for laboratory research use only.
- High purity (99.85%) suitable for research applications.
- Hydrochloride salt form to aid handling and solubility considerations.
- Available in small research pack sizes, including 10 mg, for synthesis workflows.
- Designed to act as a CRBN-binding E3 ligase ligand in PROTAC constructs.
- Recommended storage: -20°C sealed; in solvent: -80°C up to 6 months or -20°C up to 1 month.
Medchemexpress LLC Thalidomide-propargyne-PEG2-COOH | 2797619-65-7 | 98.7% | C21H20N2O8 | 10MG
Thalidomide-Propargyne-PEG2-COOH is a thalidomide-derived E3 ligase ligand-linker conjugate designed for use in PROTAC development and bioconjugation workflows. It incorporates a CRBN-binding thalidomide core, a short PEG2 spacer, and a terminal propargyne for click chemistry; supplied as a solid with high reported purity and good DMSO solubility.
Medchemexpress LLC (S)-thalidomide-4-oh | 2357105-36-1 | 98.0% | 274.23 g/mol | C13H10N2O5 | 50 MG
(S)-Thalidomide-4-OH is the S-enantiomer of thalidomide-4-OH, a thalidomide-derived cereblon ligand used in chemical biology and medicinal chemistry. Supplied as a solid research reagent, it is commonly used to recruit CRBN in PROTAC design and as a building block for medicinal chemistry.
- S-enantiomer of thalidomide-4-OH for stereospecific studies.
- Cereblon (CRBN) ligand for E3 ligase recruitment.
- Suitable building block for PROTAC synthesis and linker chemistry.
- Off-white to light yellow solid; typical pack size 50 mg.
- Reported purity 98.0% and molecular weight 274.23 g/mol.
Medchemexpress LLC Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride | 2245697-84-9 | MFCD31656717 | 98.3% | 542.97 | C23H31ClN4O9 | 50 MG
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) E3 ligase ligand provided as a hydrochloride salt for research use in PROTAC design and chemical biology. Supplied as a solid with defined molecular properties and high reported purity, it serves as a linker/ligand building block for medicinal chemistry and degradation probe synthesis.
- High purity (>98%).
- Solid, off-white to yellow appearance.
- Molecular formula C23H31ClN4O9; molecular weight 542.97.
- Suitable as a CRBN E3 ligase ligand in PROTAC and protein degradation studies.
- Available in milligram-scale quantities for laboratory research.