Lactams
Medchemexpress LLC Thalidomide-PEG5-NH2 hydrochloride | 2703775-06-6 | MFCD34550803 | 95.2% | 529.97 g·mol⁻¹ | C23H32ClN3O9 | 5 MG
Thalidomide-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon (CRBN) binding moiety with a PEG5 amine linker, supplied as the hydrochloride salt. It is intended for use in PROTAC design and chemical biology research involving CRBN-mediated protein degradation.
- Cereblon-binding thalidomide-derived ligand.
- PEG5 amine linker provides a flexible spacer for conjugation.
- Hydrochloride salt improves solubility and handling.
- Characterized by CAS 2703775-06-6 and molecular weight 529.97 g·mol⁻¹.
- Purity approximately 95.2% by LCMS.
- Intended for research use in targeted protein degradation studies.
Abcam (R,S)-Lenalidomide, Thalidomide analog, TNF alpha inhibitor, 25MG
MW 259.26 Da, Purity >98%. Thalidomide (ab120032) analog and TNF-α inhibitor. Potent antitumor and anti-inflammatory effects. Modulates and potentiates host immune responses against multiple myeloma. Active in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC CD3 epsilon Canine 50ug | 50ug
The CD3 protein on lymphocytes is a component of the TCR-CD3 complex and is critical for adaptive immune responses When APC is activated TCR signals transmitted by CD3D CD3E CD3G and CD3Z initiate pathways through ITAM CD3 epsilon Protein Canine (HEK293 Fc) is the recombinant canine-derived CD3 epsilon protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC 2-(2,6-dioxopiperidin-3-yl)-4,5-difluoroisoindoline-1,3-dione | 2222115-19-5 | >98.0% | 294.21 g·mol⁻¹ | C13H8F2N2O4 | 50 MG
Thalidomide-4,5-F is a fluorinated analogue of thalidomide that serves as a cereblon (CRBN) ligand for E3 ligase recruitment and targeted protein degradation research. It promotes ubiquitinylation of proteins and is suitable for derivatization at its fluorine positions, making it a useful building block in PROTAC and molecular glue chemistries.
- Promotes ubiquitinylation of proteins.
- Useful as a cereblon ligand for E3 ligase recruitment and PROTAC synthesis.
- Fluorine positions amenable to further derivatization.
- High purity (>98.0%).
- Chemical formula C13H8F2N2O4; molecular weight 294.21 g·mol⁻¹.
- Appearance: white to off-white solid; available in multiple sizes.
U.S. Pharmacopeia Sulbactam, 68373-14-8, MFCD00867005, 250mg
Molecular formula C8H11NO5S, Molecular weight 233.24, Melting Point 298.4 - 303.8 °F (148 - 151 °C) (also reported as 170 °C), Synonyms: Penicillanic acid 1,1-dioxide. Cold Shipment Required
Medchemexpress LLC 2-(2,6-dioxopiperidin-3-yl)-4,5-difluoroisoindoline-1,3-dione | 2222115-19-5 | >98.0% | 294.21 g/mol | C13H8F2N2O4 | 1 G
Thalidomide-4,5-F is a fluorinated analogue of thalidomide used as a cereblon (CRBN) E3 ligase ligand in research. It promotes ubiquitinylation of target proteins and can be derivatized via substitution at the fluorine positions. Supplied as a powder with high reported purity for use in chemical biology and medicinal chemistry studies.
- Fluorinated thalidomide analogue enabling derivatization via fluorine substitution
- Acts as a cereblon (CRBN) E3 ligase ligand for targeted protein ubiquitination
- Promotes ubiquitinylation of proteins in biochemical assays
- High reported purity (≥98.0%) suitable for research use
- Powder form compatible with synthetic and analytical workflows
- Molecular formula C13H8F2N2O4 and molecular weight 294.21 g/mol