Lactams
Medchemexpress LLC Sulbactam pivoxil | 69388-79-0 | MFCD00867003 | 98.0% | 347.38 g·mol⁻¹ | C14H21NO7S | 1 ML
Sulbactam pivoxil is the pivoxil prodrug of sulbactam, a β-lactamase inhibitor used in antibacterial research. It is supplied for research and analytical applications and is available as an analytical solid or as a ready-to-use 10 mM solution in DMSO.
- Available as solid and 10 mM solution in DMSO.
- Purity 98.0%.
- Molecular weight 347.38 g·mol⁻¹.
- Chemical formula C14H21NO7S.
- Recommended storage: powder -20°C for long term; in solvent -80°C for extended storage.
- Supplied with datasheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC Sulbactam | 68373-14-8 | 100.0% | 1 ML
Sulbactam is a competitive, irreversible beta-lactamase inhibitor that demonstrates antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex. It exhibits a wide range of antibacterial activity against both Gram-positive and Gram-negative aerobic and anaerobic bacteria.
- Competitive, irreversible beta-lactamase inhibitor
- Antimicrobial against multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Wide range of antibacterial activity
- Active against Gram-positive and Gram-negative aerobic and anaerobic bacteria
- For research use only
Medchemexpress LLC Sulbactam sodium | 69388-84-7 | MFCD01750374 | 99.4% | 255.22 g/mol | C8H10NNaO5S | 10 MG
Sulbactam sodium is the sodium salt of sulbactam, supplied as a high-purity analytical standard for research and assay applications. It is characterized for use in method development, quality control, and analytical testing where a well-defined beta-lactamase inhibitor reference is required.
- Sodium salt form of sulbactam.
- Competitive, irreversible β-lactamase inhibitor.
- Provided as an analytical reference standard for research and assays.
- High assay purity (reported ~99.4%).
- Available in small sizes suitable for laboratory use, e.g., 10 MG.
Medchemexpress LLC Sulbactam pivoxil | 69388-79-0 | MFCD00867003 | 98.0% | 347.38 | C14H21NO7S | 100 MG
Sulbactam pivoxil is the pivoxil ester prodrug of sulbactam, a β-lactamase inhibitor supplied as a research/analytical standard. The material is provided as a white to off-white solid with reported purity of 98.0% and a molecular weight of 347.38, and is used to support studies of oral bioavailability, pharmacokinetics, and β-lactamase inhibition.
- Prodrug form improves oral absorption compared with sulbactam.
- Useful as a reference standard for pharmacokinetic and microbiology studies.
- High reported purity supports analytical and formulation work.
- Available in solid and ready-to-use solution formats for flexibility.
- Recommended storage conditions provided to preserve stability.
Medchemexpress LLC Sulbactam | 68373-14-8 | 100.0% | 100 MG
Sulbactam is a competitive, irreversible beta-lactamase inhibitor. It exhibits antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex and possesses a broad spectrum of antibacterial activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. It is suitable for use as a laboratory chemical and in the manufacture of substances.
- Competitive, irreversible beta-lactamase inhibitor
- Antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Broad spectrum antibacterial activity
- Solid form, light yellow to yellow in color
- Suitable for laboratory chemical applications
- Melting point: 154-157°C
- Boiling point: 356°C at 760 mmHg
- Flash point: 297.1°C
- For research use only
eMolecules 68373-14-8 | Medchem Express | Sulbactam | 100mg | 446272524 | HY-B0334 | 233.24 | C8H11NO5S
Medchem Express | Sulbactam | 100mg | 446272524 | HY-B0334 | 68373-14-8 | 233.240 | C8H11NO5S
U.S. Pharmacopeia Sulbactam, 68373-14-8, MFCD00867005, 250mg
Molecular formula C8H11NO5S, Molecular weight 233.24, Melting Point 298.4 - 303.8 °F (148 - 151 °C) (also reported as 170 °C), Synonyms: Penicillanic acid 1,1-dioxide. Cold Shipment Required
Apexbio Technology LLC Tazobactam (sodium salt) 89785-84-2 250mg
Tazobactam sodium salt (CAS 89785-84-2) is a small-molecule inhibitor targeting -lactamases It is designed to irreversibly bind to -lactamases thereby preventing the enzyme-mediated hydrolysis of -lactam antibiotics Tazobactam sodium salt exerts its biological activity primarily through -lactamase inhibition In microbiological assays tazobactam demonstrates intrinsic antibacterial activity against several Acinetobacter strains typically with MIC values of 8 mg/L (range 2 32 mg/L) Based on these pharmacological properties tazobactam sodium salt holds research potential in microbiological assessments and efficacy evaluations of -lactam antibiotic combinations
Medchemexpress LLC Tetrazine-tagged thalidomide | 2087490-42-2 | 98.6% | 571.58 g/mol | C29H29N7O6 | 100 MG
Tz-Thalidomide is a tetrazine-tagged derivative of thalidomide used in bioorthogonal click-chemistry and as an E3 ligase ligand for biochemical research. It contains a reactive tetrazine group for rapid conjugation via inverse electron demand Diels-Alder reactions and has been characterized for binding to BRD4.
- Tetrazine moiety enables rapid inverse electron demand Diels-Alder (iEDDA) click reactions.
- Functions as an E3 ligase ligand for targeted protein interaction studies.
- Documented binding affinity to BRD4 in biochemical assays.
- High purity suitable for research applications.
- Available as a solid and as a 10 mM solution in DMSO for experimental flexibility.
Medchemexpress LLC Thalidomide-5-methyl | 40313-92-6 | MFCD30290642 | 99.9% | 272.26 g·mol-1 | C14H12N2O4 | 5 MG
Thalidomide-5-methyl is a thalidomide-derived cereblon (CRBN) ligand used to recruit the CRBN E3 ligase subunit in chemical biology and targeted protein degradation applications. It is provided as a research-grade small molecule suitable for use as a CRBN-binding moiety in PROTAC synthesis.
- Cereblon (CRBN) ligand for recruiting E3 ligase in PROTAC design.
- High purity suitable for research applications (99.87%).
- Molecular formula C14H12N2O4 and molecular weight 272.26 g·mol-1.
- Supplied in milligram-scale quantities for synthesis and assay development.
- Useful as a modular CRBN-binding building block in chemical biology experiments.
Medchemexpress LLC Thalidomide-4-O-C4-NH2 hydrochloride | 2376990-29-1 | MFCD32705123 | 99.4% | 381.81 | C17H20ClN3O5 | 5 MG
Thalidomide-4-O-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate supplied as the hydrochloride salt for use in PROTAC research. It couples a thalidomide-derived cereblon ligand to a four-carbon alkyl linker terminating in a primary amine, enabling conjugation to target-binding moieties. The material is intended for laboratory research use only.
- High purity (99.35%).
- Hydrochloride salt form for handling and stability.
- Molecular weight 381.81.
- Molecular formula C17H20ClN3O5.
- Available in small research quantities (5 mg and up).
- Intended for use in PROTAC design and cereblon-based degrader development.
Medchemexpress LLC Thalidomide-5-PEG7-NH2 hydrochloride | 618.07 g/mol | C27H40ClN3O11 | 10 MG
Thalidomide-5-PEG7-NH2 hydrochloride is a thalidomide-derived cereblon ligand with a PEG7 spacer provided as the hydrochloride salt. It is designed for use as an E3 ligase ligand in PROTAC and ligand-linker conjugate synthesis and is supplied as a solid for research applications.
- Thalidomide-derived cereblon ligand for recruitment of CRBN.
- PEG7 spacer offers a flexible linker for conjugation to target ligands.
- Provided as the hydrochloride salt to aid handling and solubility.
- White to off-white solid physical form.
- Molecular formula C27H40ClN3O11 and molecular weight 618.07 g/mol.
- Store sealed at -20°C; in solution store at -80°C for up to 6 months or at -20°C for up to 1 month.
- Available in small mg quantities for laboratory research use.
Medchemexpress LLC Tz-thalidomide | 2087490-42-2 | 98.6% | 571.58 | C29H29N7O6 | 10 MG
Tz-Thalidomide is a tetrazine-tagged derivative of thalidomide used in degrader and click-chemistry research. It serves as an E3 ligase ligand and contains a tetrazine group capable of undergoing inverse electron-demand Diels-Alder (iEDDA) reactions with trans-cyclooctene (TCO) partners. Reported biochemical data indicate binding affinity for BRD4. Typical purity is 98.6% and the compound is supplied as a solid and as a 10 mM solution in DMSO.
Medchemexpress LLC Thalidomide 5-fluoride | 835616-61-0 | 100.0% | 276.22 | C13H9FN2O4 | 1 ML
Thalidomide 5-fluoride is a thalidomide-derived cereblon ligand used as a building block in targeted protein degradation (PROTAC) research and related chemical biology applications. It is supplied as both solid material and pre-formulated DMSO solutions to facilitate linker conjugation and assay use.
- Thalidomide-based cereblon ligand for CRBN recruitment.
- Cas number: 835616-61-0.
- Molecular formula C13H9FN2O4; molecular weight 276.22 g/mol.
- Purity reported at 99.96% (analytical).
- Available as 10 mM solution in DMSO (1 mL) and as solid in multiple package sizes.
- Storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
Medchemexpress LLC Thalidomide-pyrrolidine hydrochloride | 2616553-35-4 | 98.0% | 335.74 g/mol | C15H14ClN3O4 | 25 MG
Thalidomide-pyrrolidine hydrochloride is an E3 ligase ligand (compound 18) used as a cereblon (CRBN) ligand in the synthesis of PROTAC degraders and other bifunctional molecules. It is supplied as an off-white to gray solid with high purity for research use.
- High purity: 98.0%.
- Molecular weight: 335.74 g/mol.
- Molecular formula: C15H14ClN3O4.
- CAS number: 2616553-35-4.
- Physical form: off-white to gray solid.
- Storage: store dry and keep cool; in solution store at -80°C (2 years) or -20°C (1 year).
- Applications: used as an E3 ligase ligand for PROTAC synthesis.