Lactams
eMolecules 28562-53-0 | 4-Acetoxy-2-azetidinone | Ambeed | MFCD00010593 | 129.115 | C5H7NO3 | 97.000 | CC(=O)OC1CC(=O)N1 | 100g | 600833386
4-Acetoxy-2-azetidinone | Ambeed | 28562-53-0 | MFCD00010593 | 129.115 | C5H7NO3 | 97.000 | CC(=O)OC1CC(=O)N1 | 100g | 600833386
Medchemexpress LLC Thalidomide-5-PEG4-NH2 hydrochloride | 2743434-24-2 | 95.2% | C21H28ClN3O8 | 10MG
Thalidomide-5-PEG4-NH2 hydrochloride is a thalidomide-derived cereblon ligand conjugated to a PEG4 linker and supplied as the hydrochloride salt. It serves as an E3 ligase ligand-linker building block for PROTAC design and related chemical biology research.
- Incorporates thalidomide-based cereblon ligand for E3 ligase recruitment.
- PEG4 linker provides a flexible spacer for bifunctional molecule design.
- Hydrochloride salt form improves handling and solubility properties.
- Intended for use in proteolysis-targeting chimera (PROTAC) synthesis.
- Molecular weight 485.92 g/mol; chemical formula C21H28ClN3O8.
- Manufacturer-reported purity 95.2% suitable for research applications.
Medchemexpress LLC Thalidomide-O-C8-Boc | 2225148-52-5 | 95.1% | 100 MG
Thalidomide-O-C8-Boc is a Thalidomide-based Cereblon ligand designed for recruiting CRBN protein. It can be linked to a target protein ligand via a linker to form PROTACs, making it suitable for research use in laboratory chemical manufacturing. This substance is stable under recommended storage conditions and is not classified as a hazardous substance or mixture.
- Used to recruit CRBN protein
- Can be linked to a target protein ligand via a linker to form PROTACs
- Suitable for laboratory chemical manufacturing
- Stable under recommended storage conditions
- Not classified as a hazardous substance or mixture
- Recommended storage temperature: -20°C, stored under nitrogen
- Molecular formula: C26H34N2O7
- Molecular weight: 486.56
- Appearance: Solid, white to off-white
Medchemexpress LLC Thalidomide-4,5-f | 2222115-19-5 | 98.0% | 294.21 g·mol⁻1 | C13H8F2N2O4 | 25 MG
Thalidomide-4,5-F is a fluorinated analogue of thalidomide used as a cereblon (E3 ligase) ligand in research. It is intended for use in PROTAC design and structure-activity studies, and the fluorine substituents allow further chemical derivatization.
- Fluorinated thalidomide analogue that binds cereblon.
- Suitable as an E3 ligase ligand for PROTAC research.
- Enables further derivatization at fluorine positions.
- High purity (≈98.0%) solid, white to off-white.
- Molecular formula C13H8F2N2O4; molecular weight 294.21 g·mol⁻1.
- Available in small research quantities, including 25 mg.
- Store powder at -20 °C for long-term storage or 4 °C for short-term storage.
Medchemexpress LLC Biotin-thalidomide | 2230857-87-9 | MFCD32851674 | 99.7% | C44H64N8O13S | 10MG
Biotin-thalidomide is a biotin-conjugated thalidomide derivative that binds the cereblon (CRBN) E3 ligase and is supplied as a high-purity reagent for use in PROTAC synthesis and biochemical assays.
- Binds cereblon (CRBN) E3 ligase
- Suitable for PROTAC synthesis and biochemical binding studies
- Facilitates affinity capture and pull-down assays via biotin tag
- Provided as a high-purity reagent for research use
- Characterized by molecular formula and SMILES for cheminformatics
Medchemexpress LLC Thalidomide-5-NH2-C8-NH2 (TFA) | 2097509-49-2 | 514.49 g/mol | C23H29F3N4O6 | 10 MG
Thalidomide-5-NH2-C8-NH2 (TFA) is a thalidomide-derived intermediate provided as the trifluoroacetic acid salt for research use and compound synthesis. It is intended for laboratory applications only and should be handled using appropriate safety procedures; store sealed at -20°C away from moisture and light. In solvent, recommended storage is -80°C for up to 6 months or -20°C for up to 1 month.
- Salt form: trifluoroacetic acid (TFA) salt.
- Suitable for compound synthesis and as a building block.
- Molecular formula: C23H29F3N4O6.
- Molecular weight: 514.49 g/mol.
- Storage: sealed at -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Thalidomide-NH-PEG1-NH2 hydrochloride | 2154342-56-8 | 99.2% | C17H21ClN4O5 | 10MG
Thalidomide-NH-PEG1-NH2 hydrochloride is a thalidomide-derived cereblon E3 ligase ligand-linker conjugate supplied as the hydrochloride salt and intended as a building block for PROTAC design and small-molecule degradation strategies. It couples a cereblon-recruiting moiety with a short PEG1 diamine linker to facilitate conjugation to target-binding ligands and streamline synthesis workflows.
- Provides thalidomide-based cereblon recruiting moiety.
- Includes a short PEG1 diamine linker for flexibility in conjugation.
- Supplied as hydrochloride salt for improved stability and handling.
- High purity suitable for synthetic applications (99.2%).
- Available in small milligram quantities for early-stage research.
eMolecules 2743434-24-2 | Medchem Express | Thalidomide-5-PEG4-NH2 (hydrochloride) | 5mg | 778475789 | HY-138785A | 485.92 | C21H28ClN3O8
AstaTech | 1-(4-BROMOPHENYL)PIPERAZINE | 1g | 302795728 | 28586 | 97.000 | 66698-28-0 | MFCD00130198 | 241.132 | C10H13BrN2
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