Lactams
Medchemexpress LLC Thalidomide-O-COOH | 1061605-21-7 | MFCD31560477 | 99.9% | 332.27 g·mol⁻¹ | C15H12N2O7 | 10 MG
Thalidomide-O-COOH is a carboxylic acid-functionalized thalidomide derivative that serves as a cereblon (CRBN) ligand for targeted protein recruitment. It is used as an E3 ligase recruiter in PROTAC design and related chemical biology research.
- Carboxylic acid-functionalized thalidomide cereblon ligand.
- Used as an E3 ligase recruiter in PROTAC design and degrader development.
- Molecular formula C15H12N2O7, molecular weight 332.27 g·mol⁻¹.
- CAS number 1061605-21-7.
- For research use only; not for human or diagnostic applications.
Medchemexpress LLC Thalidomide-O-COOH | 1061605-21-7 | MFCD31560477 | 99.9% | 332.27 | C15H12N2O7 | 25 G
Thalidomide-O-COOH is a thalidomide-derived cereblon (CRBN) ligand used as an E3 ligase recruiter in PROTAC and chemical biology research. It is supplied as a solid research reagent with high purity and characterized molecular properties for use in biochemical and cellular assays.
- High purity: 99.85%.
- Molecular formula: C15H12N2O7.
- Molecular weight: 332.27 g/mol.
- Appearance: solid, white to off-white.
- Available package sizes include 25 G for bulk research use.
- Intended use: cereblon recruitment and PROTAC design in research applications.
Medchemexpress LLC Thalidomide-CH2NH2 hydrochloride | 444287-40-5 | MFCD32183715 | 98.0% | 323.73 g/mol | C14H14ClN3O4 | 10 MG
Thalidomide-CH2NH2 hydrochloride is a thalidomide analogue supplied as the hydrochloride salt for research use. It features a primary aminomethyl substituent that enables further functionalization and utility as a ligand-like scaffold in biochemical studies. The compound is provided as a high-purity solid suitable for synthetic chemistry and assay development.
- Contains a primary aminomethyl group for synthetic functionalization.
- Supplied as the hydrochloride salt for improved stability and handling.
- High purity suitable for research and assay development.
- Serves as a ligand scaffold for E3 ligase-related studies.
- Available in small-scale quantities for discovery workflows.
Medchemexpress LLC Thalidomide-5-O-C3-NH2 hydrochloride | 2694727-94-9 | MFCD34475114 | 99.1% | 367.78 g/mol | C16H18ClN3O5 | 10 MG
Thalidomide-5-O-C3-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied as the hydrochloride salt for use as a building block in targeted protein degradation research and PROTAC design. It is provided as a solid with supporting analytical data for research use.
- Acts as a cereblon-binding ligand for CRBN recruitment.
- Enables linker conjugation for PROTAC assembly.
- Supplied with high purity (99.08%).
- Provided as a solid suitable for long-term storage under recommended conditions.
- Analytical data and COA available to support research use.
Cayman Chemical AzIdo-ThalIdomIde 5mg
A PROTAC building block; contains thalidomide, which is a ligand for the E3 ubiquitin ligase cereblon, and can be conjugated to alkynylated ligands for target proteins via click chemistry; has been used in the synthesis of a SirReal-based PROTAC for the degradation of Sirt2 in cells
Medchemexpress LLC Thalidomide-5-PEG7-NH2 hydrochloride | 618.07 g/mol | C27H40ClN3O11 | 10 MG
Thalidomide-5-PEG7-NH2 hydrochloride is a thalidomide-derived cereblon ligand with a PEG7 spacer provided as the hydrochloride salt. It is designed for use as an E3 ligase ligand in PROTAC and ligand-linker conjugate synthesis and is supplied as a solid for research applications.
- Thalidomide-derived cereblon ligand for recruitment of CRBN.
- PEG7 spacer offers a flexible linker for conjugation to target ligands.
- Provided as the hydrochloride salt to aid handling and solubility.
- White to off-white solid physical form.
- Molecular formula C27H40ClN3O11 and molecular weight 618.07 g/mol.
- Store sealed at -20°C; in solution store at -80°C for up to 6 months or at -20°C for up to 1 month.
- Available in small mg quantities for laboratory research use.
eMolecules (R)-1-(3-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYL)-3-(3,4-DIMETHOXYPHENYL)PROPAN-1-OL | 1013621-67-4 | MFCD17170917 | 1g
AstaTech | (R)-1-(3-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYL)-3-(3,4-DIMETHOXYPHENYL)PROPAN-1-OL | 1g | 248480807 | 32403 | 97.000 | 1013621-67-4 | MFCD17170917 | 402.606 | C23H34O4Si
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Medchemexpress LLC Thalidomide-O-amido-PEG-C2-NH2 hydrochloride | 2204226-02-6 | 98.1% | 5MG
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride | 2204226-02-6 | 98.1% | 5MG
![eMolecules 2-[3-[tert-Butyl(dimethyl)silyl]oxypropoxy]acetonitrile | 1430412-80-8 | | 500mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502168186.JPG-250.jpg)
eMolecules 2-[3-[tert-Butyl(dimethyl)silyl]oxypropoxy]acetonitrile | 1430412-80-8 | | 500mg
Synthonix - Stock | 2-[3-[tert-Butyl(dimethyl)silyl]oxypropoxy]acetonitrile | 500mg | 525932268 | T10078 | | 1430412-80-8 | | 229.395 | C11H23NO2Si
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