Lactams
Medchemexpress LLC Thalidomide | 50-35-1 | MFCD00153873 | 99.96% | 258.23 | 100 MG
Thalidomide (Standard) is an analytical standard intended for research and analytical applications. It inhibits cereblon (CRBN), part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, and possesses immunomodulatory, anti-inflammatory, and anti-angiogenic cancer properties. It can also act as a molecular glue to potentiate substrate. This analytical standard is suitable for various assays and commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Inhibits cereblon (CRBN)
- Possesses immunomodulatory, anti-inflammatory, and anti-angiogenic cancer properties
- Can act as a molecular glue to potentiate substrate
- Suitable for assays
- Used in HPLC, GC, and MS experiments
Medchemexpress LLC Thalidomide (Standard) | 50-35-1 | 100.0% | 258.23 | 50 MG
Thalidomide (Standard) | 50-35-1 | 100.0% | 258.23 | 50 MG
Medchemexpress LLC Acy-957 | 1609389-52-7 | 99.6% | 429.54 g/mol | C24H23N5OS | 50 MG
ACY-957 is an orally active, selective small-molecule inhibitor of histone deacetylase isoforms HDAC1 and HDAC2, used for research into epigenetic regulation. It shows potent activity against HDAC1 and HDAC2, reduced activity against HDAC3, and no measurable inhibition of several class II HDACs. The compound is supplied as a high-purity solid and is available in solution formats for assay use.
- Potent inhibition of HDAC1 and HDAC2.
- High selectivity over HDAC3 and class II HDACs.
- Suitable for in vitro and in vivo formulation protocols.
- High reported purity for reliable experimental results.
- Provided as a solid and as ready-to-use DMSO solutions.
- Documented storage and stability conditions for sample handling.
Medchemexpress LLC Thalidomide-4-O-C14-NH2 hydrochloride | 99.9% | 522.08 | C27H40ClN3O5 | 10 MG
Thalidomide-4-O-C14-NH2 hydrochloride is a carbon-14 radiolabeled thalidomide derivative used as a cereblon (CRBN) ligand in research applications, including PROTAC assembly. The product is supplied as the hydrochloride salt with high purity and characterized molecular properties for use in biochemical and pharmacokinetic studies.
Selleck Chemical LLC Brucine sulfate heptahydrate
Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons
Selleck Chemical LLC Brucine sulfate heptahydrate
Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons
eMolecules 68373-14-8 | Medchem Express | Sulbactam | 100mg | 446272524 | HY-B0334 | 233.24 | C8H11NO5S
Medchem Express | Sulbactam | 100mg | 446272524 | HY-B0334 | 68373-14-8 | 233.240 | C8H11NO5S
Medchemexpress LLC (R)-Thalidomide | 2614-06-4 | 99.8% | 258.23 | 1 MG
(R)-Thalidomide, also known as (R)-(+)-Thalidomide, is the R-enantiomer of Thalidomide, possessing psychomotor stabilizing properties. It is intended for research use only and is not sold to patients.
- (R)-Thalidomide binds more strongly to the selective sites of MIP (molecularly imprinted polymer) compared to other forms, indicating distinct biological entities.
- In vivo studies in F344 rats with 9L gliosarcoma tumors showed that serum and tissue concentrations of (R)-thalidomide were 40-50% greater than those of (S)-thalidomide.
- Co-administration of BCNU or cisplatin with thalidomide did not alter the concentration enantioselectivity in rats.
Selleck Chemical LLC Sulbactam S1958-10mg
Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0 8 M
TARGETMOL CHEMICALS INC TIGEMONAM 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Tigemonam is a monobactam. Tigemonam has potent activity against Gram-negative aerobic bacterial pathogens. purity: 99%
Medchemexpress LLC N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide TFA salt | 1799711-25-3 | MFCD31560484 | 99.9% | 516.42 g·mol⁻¹ | C21H23F3N4O8 | 2 G
Thalidomide-O-amido-C4-NH2 TFA is a thalidomide-derived cereblon ligand-linker conjugate provided as the trifluoroacetate (TFA) salt for use in PROTAC design and other chemical biology applications. It is supplied as a white to off-white solid with high analytical purity and a molecular weight of 516.42 g·mol⁻¹.
- Thalidomide-derived cereblon ligand-linker conjugate.
- Provided as the trifluoroacetate (TFA) salt.
- High purity by LCMS (reported 99.92%).
- White to off-white solid appearance.
- Molecular formula C21H23F3N4O8; molecular weight 516.42 g·mol⁻¹.
- Intended for research use only; not for human or diagnostic use.
Medchemexpress LLC Thalidomide-4-O-C9-NH2 (hydrochloride) | 99.3% | 451.94 | 25 MG
Thalidomide-4-O-C9-NH2 hydrochloride is a chemical compound for laboratory research and the manufacture of substances. This compound is stable under recommended storage conditions, which include sealed storage at -20°C, away from moisture and light. If in solvent, it can be stored at -80°C for 6 months or -20°C for 1 month.
- Intended for laboratory research and substance manufacturing
- Molecular weight of 451.94
- Purity of 99.26%
- Stable under recommended storage conditions
- Store at -20°C, sealed, away from moisture and light
- In solvent, store at -80°C for 6 months or -20°C for 1 month
- Can be shipped at room temperature if transit is less than 2 weeks
![Medchemexpress LLC 5-[(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-isoindole-1,3-dione | 2357110-24-6 | MFCD34563706 | 98.0% | 311.29 g/mol | C16H13N3O4 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000284650.png-250.jpg)
Medchemexpress LLC 5-[(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-isoindole-1,3-dione | 2357110-24-6 | MFCD34563706 | 98.0% | 311.29 g/mol | C16H13N3O4 | 50 MG
Thalidomide-5-NH-C-alkyne is an E3 ligase ligand-linker conjugate that contains a terminal alkyne for bioorthogonal conjugation. It is provided as a small-quantity research reagent intended for PROTAC development and target protein conjugation. Reported properties include a molecular formula of C16H13N3O4, a molecular weight of 311.29 g/mol, and a reported purity of 98.0%.
- Contains an E3 ligase ligand with a terminal alkyne for conjugation.
- Designed for PROTAC development and target protein degradation studies.
- Reported purity 98.0% suitable for research applications.
- Provided as a small-quantity reagent (50 mg) for synthetic chemistry workflows.
- Molecular formula C16H13N3O4; molecular weight 311.29 g/mol.
- Store and handle according to supplier safety data sheet recommendations.
Medchemexpress LLC 6h-Thieno[3,2-f]triazolo[4,3-a]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, cyclopropyl ester, (6s)- | 3077900-08-1 | 98.31% | 440.95 | 1 ML
DDL-357 is a potent secreted clusterin enhancer. It reduces phospho-tau in the brain and improves memory in the murine 3xTg-AD model.
- Potent secreted clusterin enhancer.
- Reduces phospho-tau in brain.
- Improves memory in the murine 3xTg-AD model.