Lactams

7-Aminocephalosporanic acid, 95-102%

CAS: 957-68-6 Molecular Formula: C₁₀H₁₂N₂O₅S Molecular Weight (g/mol): 272.27 MDL Number: MFCD00005177 InChI Key: HSHGZXNAXBPPDL-HZGVNTEJSA-N Synonym: 7-aminocephalosporanic acid,7-aca,7-aminocephalosporinic acid,7beta-aminocephalosporanic acid,7-acs,unii-9xi67897rg,7r-7-aminocephalosporanic acid,7r-7-aminocephalosporanate,cephalosporanic acid, 7-amino,6r,7r-3-acetoxymethyl-7-amino-8-oxo-5-thia-1-azabicyclo 4.2.0 oct-2-ene-2-carboxylic acid PubChem CID: 441328 ChEBI: CHEBI:2255 IUPAC Name: (6R,7R)-3-(acetyloxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid SMILES: CC(=O)OCC1=C(N2C(C(C2=O)N)SC1)C(=O)O

7-Aminodesacetoxycephalosporanic Acid 98.0+%, TCI America™

CAS: 22252-43-3 Molecular Formula: C8H10N2O3S Molecular Weight (g/mol): 214.239 MDL Number: MFCD00151456 InChI Key: NVIAYEIXYQCDAN-CLZZGJSISA-N Synonym: 7-aminodesacetoxycephalosporanic acid,6r,7r-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo 4.2.0 oct-2-ene-2-carboxylic acid,7-aminodeacetoxycephalosporanic acid,7-adca,unii-anm3msm8tn,anm3msm8tn,7beta-amino-3-methyl-3-cephem-4-carboxylic acid,7beta-amino-3-methylceph-3-em-4-carboxylic acid,7-amino desacetoxy cephalosporanic acid,7beta-aminodeacetoxycephalosporanic acid PubChem CID: 33498 ChEBI: CHEBI:64984 IUPAC Name: (6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid SMILES: CC1=C(N2C(C(C2=O)N)SC1)C(=O)O

7-Aminocephalosporanic Acid 97.0+%, TCI America™

CAS: 957-68-6 Molecular Formula: C10H12N2O5S Molecular Weight (g/mol): 272.275 MDL Number: MFCD00005177 InChI Key: HSHGZXNAXBPPDL-HZGVNTEJSA-N Synonym: 7-aminocephalosporanic acid,7-aca,7-aminocephalosporinic acid,7beta-aminocephalosporanic acid,7-acs,unii-9xi67897rg,7r-7-aminocephalosporanic acid,7r-7-aminocephalosporanate,cephalosporanic acid, 7-amino,6r,7r-3-acetoxymethyl-7-amino-8-oxo-5-thia-1-azabicyclo 4.2.0 oct-2-ene-2-carboxylic acid PubChem CID: 441328 ChEBI: CHEBI:2255 IUPAC Name: (6R,7R)-3-(acetyloxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid SMILES: CC(=O)OCC1=C(N2C(C(C2=O)N)SC1)C(=O)O

7-Aminodesacetoxycephalosporanic Acid, British Pharmacopoeia (BP) Reference Standard, MilliporeSigma™ Supelco™

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

Sigma Aldrich 2-Chloro-6-methylbenzoic acid

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

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Sulbactam 98.0+%, TCI America™

CAS: 68373-14-8 Molecular Formula: C8H11NO5S Molecular Weight (g/mol): 233.24 MDL Number: MFCD00867005 InChI Key: FKENQMMABCRJMK-RITPCOANSA-N Synonym: sulbactam,sulbactam acid,penicillanic acid sulfone,sulbactamum,betamaze,2s,5r-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo 3.2.0 heptane-2-carboxylic acid 4,4-dioxide,penicillanic acid 1,1-dioxide,unii-s4tf6i2330,penicillanic acid dioxide,chembl403 PubChem CID: 130313 ChEBI: CHEBI:9321 IUPAC Name: (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ⁶-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid SMILES: CC1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O

Aztreonam 98.0+%, TCI America™

CAS: 78110-38-0 Molecular Formula: C13H17N5O8S2 Molecular Weight (g/mol): 435.426 MDL Number: MFCD00072145 InChI Key: WZPBZJONDBGPKJ-PSGLRMFWSA-N Synonym: trans-2-1-2-aminothiazol-4-yl-2-2-methyl-4-oxo-1-sulphoazetidin-3-yl amino-2-oxoethylidene amino oxy-2-methylpropionic acid,2-1-2-amino-4-thiazolyl-2-2r-2alpha-methyl-4-oxo-1-sulfo-3beta-azetidinyl amino-2-oxoethylidene amino oxy-2-methylpropanoic acid PubChem CID: 56842327 IUPAC Name: 2-[(E)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2R,3R)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid SMILES: CC1C(C(=O)N1S(=O)(=O)O)NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)N

Medchemexpress LLC Thalidomide-NH-PEG3-propionic acid | 2138440-82-9 | 99.7% | 477.46 | 100 MG

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Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a 3-unit PEG linker used in PROTAC technology. This product is for research use only, intended for experienced personnel in appropriately equipped and authorized facilities.

• Synthesized E3 ligase ligand-linker conjugate
• Incorporates Thalidomide based cereblon ligand
• Uses a 3-unit PEG linker
• Utilized in PROTAC technology
• Exploits intracellular ubiquitin-proteasome system for selective protein degradation

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Medchemexpress LLC Thalidomide-NH-PEG3-propionic acid | 2138440-82-9 | 99.72% | 477.46 | 25 MG

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Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate used in PROTAC technology. It incorporates a thalidomide-based cereblon ligand and a 3-unit PEG linker.

• PROTACs contain two different ligands connected by a linker.
• One ligand is for an E3 ubiquitin ligase and the other is for the target protein.
• PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
• Stable under recommended storage conditions.
• Recommended storage temperature: 4°C, protect from light.

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Medchemexpress LLC Thalidomide-O-C2-acid | 2369068-42-6 | 95.0% | 346.29 g/mol | C16H14N2O7 | 5 MG

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Thalidomide-O-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates a thalidomide-based cereblon ligand with a two-carbon linker. It is intended as a research-grade building block for PROTAC synthesis and related chemical biology applications, and is supplied with reported analytical data suitable for experimental use.

• E3 ligase ligand-linker conjugate for PROTAC design.
• Molecular formula C16H14N2O7.
• Molecular weight 346.29 g/mol.
• CAS number 2369068-42-6.
• Reported purity 95.0%.
• Available in small milligram pack sizes for research use.

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Medchemexpress LLC 11-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}undecanoic acid | 2379870-45-6 | MFCD03424822 | 99.1% | C24H30N2O7 | 10MG

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Thalidomide-4-O-C10-COOH is a thalidomide-derived cereblon (CRBN) E3 ligase ligand-linker conjugate provided for research use as a synthetic intermediate in the preparation of proteolysis-targeting chimeras (PROTACs). The molecule features a ten-carbon linker terminating in a carboxylic acid, and is supplied as a solid with formula C24H30N2O7 and molecular weight 458.50 g·mol⁻¹.

• Thalidomide-based cereblon (CRBN) ligand-linker conjugate.
• Suitable for PROTAC synthesis and E3 ligase recruitment studies.
• Contains a C10 linker with a terminal carboxylic acid for conjugation.
• High reported purity (99.1%).
• Supplied as a solid; molecular formula C24H30N2O7, molecular weight 458.50 g·mol⁻¹.
• For research use only; not for human therapeutic use.

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Medchemexpress LLC 7-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}heptanoic acid | 2169266-69-5 | MFCD32063464 | 99.3% | C20H22N2O7 | 10MG

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Thalidomide-O-C6-COOH is a thalidomide-based cereblon (CRBN) E3 ligase ligand-linker conjugate terminating in a six-carbon carboxylic acid. It is used as a building block in PROTAC synthesis and chemical biology research, providing a convenient carboxylic acid handle for linker attachment and efficient recruitment of CRBN.

• Used in PROTAC design to recruit cereblon (CRBN) E3 ligase.
• Thalidomide-based ligand with a six-carbon carboxylic acid linker.
• High purity, 99.3% (reported).
• Soluble ≥100 mg/mL in DMSO.
• Off-white to light yellow solid suitable for synthesis.
• Molecular formula C20H22N2O7; molecular weight 402.40 g·mol⁻1.
• Storage recommendations provided for powder and solutions to maintain stability.

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eMolecules​ Thalidomide-Acid | 1061605-21-7 | | 1g

Broadpharm | Thalidomide-Acid | 1g | 550804650 | BP-24447 | 98.000 | 1061605-21-7 | | 332.268 | C15H12N2O7

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eMolecules​ Broadpharm / D-acid-PEG4-Thalidomide-5-(PEG4-acid) / 100mg / 779524498 / BP-29724 / 98.000 / / [null] / 770.782 / C35H50N2O17

Broadpharm / D-acid-PEG4-Thalidomide-5-(PEG4-acid) / 100mg / 779524498 / BP-29724 / 98.000 / / [null] / 770.782 / C35H50N2O17

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Sigma Aldrich Fine Chemicals Biosciences 7-Aminodesacetoxycephalosporanic acid | 22252-43-3 | MFCD09750368 | 250MG

7-Aminodesacetoxycephalosporanic acid | Mol Wt: 214.24 | 22252-43-3 | MFCD09750368 | 250MG

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