Lactones
eMolecules 720679-54-9 | 3,5-Dichloro-4-(hydroxymethyl)phenol | MFCD06797936 | 1g
Ambeed | 3,5-Dichloro-4-(hydroxymethyl)phenol | 1g | 602850251 | A500317 | 720679-54-9 | MFCD06797936 | 193.020 | C7H6Cl2O2
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Medchemexpress LLC Gamma-Mangostin | 31271-07-5 | 396.43 | 1 ML
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and a potent cyclooxygenase-2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. It functions by binding to the thyroxine (T4)-binding sites, which stabilizes the TTR tetramer. This compound exhibits anti-inflammatory, antibacterial, antioxidant, and anticancer activities, making it suitable for studies related to metabolic disorders such as diabetes.
- Inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM).
- Reduces the perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM).
- Possesses anti-inflammatory, antibacterial, antioxidant, and anticancer activities.
- Can be utilized in the study of metabolic disorders such as diabetes.
Medchemexpress LLC Interferon gamma receptor 1 (rat) Fc fusion protein | >95.0% | 50 UG
Recombinant rat interferon gamma receptor 1 extracellular domain Fc fusion protein expressed in HEK293 cells. Supplied lyophilized in a buffered formulation, it is intended for binding assays, receptor/ligand studies, and assay development that require the rat IFN-gamma receptor extracellular domain.
- Expressed in HEK293 cells for mammalian glycosylation.
- C-terminal human Fc fusion to facilitate detection and purification.
- High purity (>95%) as verified by reducing SDS-PAGE.
- Lyophilized formulation for extended shelf life.
- Recommended reconstitution ≥100 μg/mL in ddH2O; store aliquots at -20°C or -80°C for long-term.
Medchemexpress LLC HY-17502 500mg , Simvastatin MK 733 CAS:79902-63-9 Purity:98%
Medchemexpress, HY-17502 500mg Simvastatin MK 733 CAS:79902-63-9 Formula:C25H38O5 Ki: 0.2 nM (HMG-CoA reductase) Purity:98% Simvastatin is a competitive inhibitor of HMG-CoA reductase with a K i of 0.2 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Gibberellin A1 | 545-97-1 | 5 MG
Gibberellin A1 is a plant hormone and a growth-promoting acid, isolated from immature seeds of *Phaseolus multiflorus*. It is the primary endogenous hormone controlling stem elongation in plants and can reverse stem growth inhibition. This product is intended for research use only, not for patient or medical applications.
- Growth-promoting acid
- Isolated from immature seeds of *Phaseolus multiflorus*
- Primary endogenous hormone controlling stem elongation
- Reverses stem growth inhibition
- Molecular Weight: 348.39
- Molecular Formula: C19H24O6
- Purity: 98.66%
Medchemexpress LLC Gamma-Mangostin | 31271-07-5 | 396.43 | 20 MG
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. It binds to thyroxine (T4)-binding sites and stabilizes the TTR tetramer. It possesses anti-inflammatory, antibacterial, antioxidant, and anticancer activities, and can be used in the study of metabolic disorders such as diabetes.
- Novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist
- Potent epoxidase 2 (COX-2) inhibitor
- Transthyroxin protein (TTR) profibrosis inhibitor
- Binds to thyroxine (T4)-binding sites and stabilizes the TTR tetramer
- Anti-inflammatory activity
- Antibacterial activity
- Antioxidant activity
- Anticancer activities
- Used in the study of metabolic disorders such as diabetes
Medchemexpress LLC Gamma-mangostin | 31271-07-5 | MFCD00951752 | 99.9% | 396.43 | C23H24O6 | 10 MG
Gamma-mangostin is a natural xanthone research compound with demonstrated activity as a competitive 5-HT2A receptor antagonist and a potent COX-2 inhibitor. It is used in studies of inflammation, receptor pharmacology, and transthyretin (TTR) stabilization. Supplied as a high-purity solid with recommended DMSO solubility and established in vivo formulation protocols.
- High purity suitable for biochemical and pharmacology assays.
- Chemical formula C23H24O6; molecular weight 396.43.
- Reported activities include 5-HT2A antagonism, COX-2 inhibition, and TTR stabilization.
- Available in small milligram quantities (including 10 MG) for screening and dose-response studies.
- Soluble in DMSO with manufacturer-recommended in vivo formulation options.
eMolecules 228421-83-8 | 3,5-Difluoro-4-(hydroxymethyl)benzonitrile | MFCD11847159 | 1g
Ambeed | (2S)-2-(4-Fluorophenyl)-2-hydroxyacetic acid | 100mg | 596330062 | A1020684 | 52923-25-8 | MFCD20643876 | 170.139 | C8H7FO3
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Apexbio Technology LLC L-161,982(Synonyms: L-161982, L161982, EP4 Receptor Antagonist L-161982, EP4 antagonist L-161982), 1mg, CAS: 147776-06-5.
L-161 982 (CAS 147776-06-5) is a selective antagonist of the prostaglandin E2 receptor subtype EP4 By specifically blocking EP4 signaling this compound modulates downstream pathways associated with inflammation and cell proliferation In vitro studies indicate that inhibition of EP4 by L-161 982 reduces ERK phosphorylation and consequently suppresses proliferation of the HCA-7 cell line Additionally rodent studies demonstrate that L-161 982 alleviates collagen-induced arthritis underscoring its utility in investigating EP4-related inflammatory processes and disease mechanisms
Medchemexpress LLC NH2 DOTA-GA | 1639843-65-4 | 100.0% | 518.56 g·mol⁻¹ | C21H38N6O9 | 25 MG
NH2 DOTA-GA is a DOTA-based bifunctional metal chelator used to prepare radionuclide drug conjugates. It is supplied as a solid powder and contains carboxylic acid groups capable of complexing metal ions, such as Gd(III).
- DOTA-based bifunctional chelator for radionuclide conjugates.
- Useful for metal ion complexation, including Gd(III).
- CAS number 1639843-65-4 for unambiguous identification.
- Molecular formula C21H38N6O9 and molecular weight 518.56 g·mol⁻¹.
- High chemical purity suitable for research applications.
- Solid powder with recommended storage at -20°C (powder) or -80°C/-20°C in solvent.
Medchemexpress LLC Recombinant rat Fc gamma RIIB (CD32b) protein, His-tag | >95.0% | 10 UG
Recombinant rat Fc gamma RIIB (CD32b) extracellular domain expressed in HEK293 cells with a C-terminal 6xHis tag. Supplied for research use in protein-protein interaction studies, this product is suitable for ELISA, SPR, and other receptor-ligand assays and is provided with guidance for storage and handling.
Sigma Aldrich Fine Chemicals Biosciences (3aR)-(+)-Sclareolide natural, 97%, FG | 564-20-5 | MFCD00134168 |
(3aR)-(+)-Sclareolide natural, 97%, FG | Purity: 97% | Mol Wt: 250.38 | 564-20-5 | MFCD00134168 |
Sigma Aldrich Fine Chemicals Biosciences gamma Valerolactone BioRen
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. gamma-ValerolactoneA(GVL) is a bio-based fully degradable non-toxic green solvent and has been aligned with Safer Solvent and Auxiliaries Use of Renewable feedstocks and Design for Degradation. Click here for more information.