Lactones
Medchemexpress LLC Interleukin-36 gamma | 50 UG
Recombinant human interleukin-36 gamma (IL-36γ, IL-1F9) is an animal-free, E. coli-expressed cytokine supplied as a lyophilized His-tagged protein. It activates NF-κB and MAPK signaling and induces chemokine expression; biological activity in A431 cells shows an ED50 <5 ng/mL. The product is formulated in PBS with trehalose, has low endotoxin, and is intended for cell-culture research use.
- Lyophilized His-tagged recombinant human IL-36γ.
- Expressed in Escherichia coli to provide animal-free material.
- Approximate molecular weight ~19 kDa by SDS-PAGE.
- Low endotoxin level (<0.1 EU per μg).
- Demonstrated biological activity: ED50 <5 ng/mL (IL-8 induction in A431 cells).
- Formulated in PBS, pH 8.0, with trehalose for stability.
- Reconstitute to 100-200 μg/mL and aliquot to avoid freeze-thaw cycles.
- For research use only; not for therapeutic or human use.
Medchemexpress LLC IFN-gamma Sheep Hi 20ug
IFN-gamma (interferon-gamma) is a type II interferon produced by T cells and NK cells which can significantly activate antibacterial antiviral and antitumor responses It acts through the JAK-STAT pathway and its receptor IFNGR1 to affect gene regulation IFN-gamma Protein Sheep (His) is the recombinant sheep-derived IFN-gamma protein expressed by E coli with N-6 His labeled tag
eMolecules AstaTech / TERT-BUTYL 2-(HYDROXYMETHYL)-1H-INDOLE-1-CARBOXYLATE / 0.25g / 261441238 / AB8707 / 95.000 / 174180-53-1 / MFCD09032312 / 247.294 / C14H17NO3
AstaTech / TERT-BUTYL 2-(HYDROXYMETHYL)-1H-INDOLE-1-CARBOXYLATE / 0.25g / 261441238 / AB8707 / 95.000 / 174180-53-1 / MFCD09032312 / 247.294 / C14H17NO3
Medchemexpress LLC NH2 DOTA-GA | 1639843-65-4 | 518.56 | C21H38N6O9 | 50 MG
NH2 DOTA-GA is a DOTA-based bifunctional metal chelator used to prepare radionuclide drug conjugates (RDCs), with carboxylic acid groups capable of complexing metal ions such as Gd(III).
- Bifunctional DOTA chelator for radiolabeling of biomolecules.
- Suitable for preparation of radionuclide-drug conjugates.
- Molecular formula C21H38N6O9; molecular weight 518.56.
- Available as a 50 mg powder; stable for 3 years at -20°C when stored as recommended.
- Listed CAS number 1639843-65-4 for unambiguous identification.
Medchemexpress LLC TC-G-1008 | 1621175-65-2 | 99.4% | 418.90 | C18H19ClN6O2S | 10 MG
TC-G-1008 (GPR39-C3) is a small-molecule, orally available agonist of the G protein-coupled receptor GPR39, supplied as a high-purity solid for in vitro and in vivo pharmacology. It exhibits sub-nanomolar potency (EC50 0.4 nM in rat, 0.8 nM in human) and is suitable for receptor pharmacology, target validation, and pharmacodynamic studies.
- Molecular formula: C18H19ClN6O2S
- Molecular weight: 418.90
- Purity: 99.4%
- Physical form: solid (powder)
- Solubility: DMSO ≥100 mg/mL; in vivo formulations ≥2.5 mg/mL
- Suggested storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years)
- Available pack sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
Medchemexpress LLC Gamma tubulin antibody (YA419) (PBS only) | affinity purified | 51 kDa | 10 UL
Gamma Tubulin Antibody is a non-conjugated, rabbit-originated IgG monoclonal antibody, targeting gamma Tubulin. It can be used as a loading control antibody. This gene encodes a member of the tubulin superfamily, with the encoded protein localizing to the centrosome where it binds to microtubules as part of the gamma-tubulin ring complex. This protein mediates microtubule nucleation and is essential for microtubule formation and cell cycle progression.
- Host: Rabbit
- Reactivity: Human, Mouse, Rat, Hamster
- Conjugation: Non-conjugated
- SwissProt ID: P23258
- Research field: Signal transduction
- Application: WB, ICC/IF, IP
- Purity: Affinity purified
- Formulation: Supplied in PBS, pH 7.4
Medchemexpress LLC Fc gamma RIIA/CD32a 500ug
Recombinant human Fc gamma RIIA (CD32a) extracellular domain (H167R allotype), expressed in HEK293 cells with a C-terminal His tag. Supplied lyophilized, the 183 amino-acid protein is provided with low endotoxin and a buffered formulation to support stability; it is suitable for binding studies, surface plasmon resonance, and other biochemical assays when reconstituted and handled according to storage recommendations.
- Recombinant extracellular domain (183 a.a.) for receptor binding studies.
- HEK293 expression ensures mammalian post-translational modifications.
- C-terminal His tag enables affinity purification and detection.
- Low endotoxin (<1 EU/μg) for sensitive bioassays.
- Lyophilized formulation for extended shelf life and transport.
- Stable under recommended storage and aliquoting conditions.
Medchemexpress LLC Fc gamma RIII/CD16 10ug | 10ug
The Fc RIIIA/CD16a protein is a receptor for IgG and is optimally activated upon binding of aggregated antigen-IgG complexes inducing antibody-dependent cellular cytotoxicity (ADCC) It mediates IgG effector function on natural killer cells limiting viral load Fc gamma RIII/CD16 Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived Fc gamma RIII/CD16 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC AMP-activated protein kinase gamma-1/beta-2/alpha-1 heterotrimer, human recombinant (His-GST) | 96.3% | 5 UG
Recombinant human AMPK heterotrimer containing γ1, β2, and α1 subunits, expressed in Sf9 insect cells and affinity-tagged with His-GST. This purified complex is provided for biochemical and cell-free assays requiring the intact AMPK enzyme complex.
- Purity 96.3% by supplier analysis.
- Expressed in Sf9 insect cells (baculovirus expression).
- His-GST tag enables affinity purification and detection.
- Approximate subunit molecular weights: ~35 kDa, ~37 kDa, ~95 kDa.
- Supplied as a 5 μg quantity suitable for assay development.
- Intended for biochemical and in vitro functional assays.
Medchemexpress LLC Fc gamma RIIB/CD32b protein, rat (HEK293-expressed, C-terminal His-tag) | 95.0% | 500 UG
Recombinant rat Fc gamma RIIB (CD32b) protein expressed in HEK293 cells with a C-terminal His tag, supplied as a purified reagent for immunology and Fc receptor-binding studies (500 μg format).
- Expressed in HEK293 cells for mammalian post-translational modifications.
- C-terminal His tag enables detection and purification.
- High purity (>95.0%) suitable for binding assays and biochemical analysis.
- Supplied in research-friendly formats including 500 μg.
- Useful for studies of IgG binding, Fc receptor signaling, and receptor-ligand interactions.
Medchemexpress LLC Fc gamma RIIA (CD32a) protein, rhesus macaque (HEK293), C-His tag | >95.0% | 10 UG
Recombinant Fc gamma RIIA (CD32a) extracellular domain from rhesus macaque, expressed in HEK293 cells and supplied as a lyophilized His-tagged protein. Designed for binding assays, protein-protein interaction studies, and functional assays involving Fc receptor signaling. Purified to high purity with low endotoxin; recommended storage at -20°C and reconstitution at ≥100 μg/mL with carrier protein for long-term stability.
- Recombinant extracellular domain of Fc gamma RIIA (CD32a) from rhesus macaque.
- Expressed in HEK293 cells with a C-terminal His tag.
- Lyophilized powder formulation for long-term storage.
- Purity greater than 95% as indicated by reducing SDS-PAGE.
- Endotoxin level below 1 EU/μg by LAL method.
- Molecular weight approximately 25-35 kDa under reducing conditions.
- Suitable for binding assays and receptor interaction studies.
Sigma Aldrich Fine Chemicals Biosciences epsilon-Decalactone >=99% | 5579-78-2 | MFCD00209538 | 100G
epsilon-Decalactone >=99% | Purity: >=99% | Mol Wt: 170.25 | 5579-78-2 | MFCD00209538 | 100G
Medchemexpress LLC IFN-gamma R1/CD119 100ug
IFN-gamma R1 (CD119) one of the subunit of IFN-gamma receptor is a receptor for IFN-gamma IFN-gamma R1 forms the functional receptor with IFN-gamma R2 Upon binding with IFN-gamma IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1] Then JAK1 and JAK2 are phosphorylated and activated and STAT1 is recruited to the receptor complex Phosphorylated STAT1 translocates to the nucleus where it regulates the expression of IFN-responsive genes (e g CD54)[2] IFN-gamma R1/CD119 Protein Mouse (HEK293 His) is a recombinant mouse IFN-gamma R1 with C-terminal 6 His tag which is produced in HEK293 cells
Medchemexpress LLC gamma-secretase modulator 6 | 1255700-88-9 | 99.7% | 442.51 | 5 MG
gamma-secretase modulator 6 is a gamma-secretase modulator that inhibits Aβ42 secretion in HEK cell lines stably expressing APP (Aβ amyloid precursor protein) with a pIC50 of 8.1. It can be used for Alzheimer's disease research.
- Inhibits Aβ42 secretion in HEK cell line stably expressing APP (Aβ amyloid precursor protein) (pIC50: 8.1)
- Can be used for research of Alzheimer's disease
- Appearance: solid
- Color: light yellow to yellow