Lactones
Medchemexpress LLC IFN-gamma Human HE 2ug
Recombinant human interferon-gamma expressed in HEK293 cells and supplied lyophilized for research use. The protein is characterized for purity, molecular mass, formulation, storage stability, and biological activity, making it suitable for cell-based assays and immunological studies.
- Produced in HEK293 mammalian expression system.
- Lyophilized formulation for long-term storage and transport.
- High purity, >95% by reducing SDS-PAGE.
- Characterized biological activity with low ED50 and high specific activity.
- Includes recommended reconstitution, aliquoting, and storage instructions.
- Sequence corresponds to the human IFN-γ mature form (UniProt P01579).
Medchemexpress LLC Gamma-glutamylcysteine TFA | 283159-88-6 | 95.2% | 364.30 | 10 MG
Gamma-glutamylcysteine TFA is an orally active, blood-brain barrier permeable dipeptide involved in regulating macrophage polarization, inducing glutathione synthesis, and improving metabolic dysfunction. It is relevant for research in various diseases.
- Orally active and blood-brain barrier permeable dipeptide.
- Activates AMPK, SIRT1, IL-4/STAT6, AC/cAMP/PI3K, IGF-1R/IRS1/PI3K, and Nrf2 signaling pathways.
- Inhibits NF-κB, JAK1/STAT1/3, MAPKs, and PI3K/Akt signaling pathways.
- Regulates macrophage polarization and modulates CD36 and GLUT4 trafficking.
- Induces glutathione synthesis, improves metabolic dysfunction, and ameliorates glucose homeostasis.
- Reduces lipid deposition, inhibits apoptosis, stabilizes mitochondria, and suppresses ferroptosis.
- Relevant for research in inflammatory bowel disease, type 2 diabetes, Alzheimer's disease, and alcoholic liver disease.
Medchemexpress LLC Fc gamma RIIB/CD32b 10ug | 10ug
Fc RIIB/CD32b proteins exhibit low affinity as complexes or receptors that aggregate the immunoglobulin Fc region ITIM phosphorylated by Fc RIIB/CD32b recruits inositol phosphatases SHIP1 and SHIP2 inhibits Ras activation down-regulates MAPK activity reduces PLC- function and results in PKC activation Inhibition of MAP kinase pathway and anti-apoptotic kinase Akt inhibit cell proliferation and survival Fc gamma RIIB/CD32b Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived Fc gamma RIIB/CD32b protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC AMPK gamma 1/beta 2/alpha 2 heterotrimer protein, human (Sf9, His-GST) | >90.0% | 50 UG
Recombinant human AMPK heterotrimer (α2, β2, γ1) expressed in Sf9 insect cells, supplied as a filtered solution with N-terminal His and GST tags for biochemical and structural studies. The preparation is formulated in a stabilizing buffer and provided for research use only.
- Source organism: human.
- Expression system: Sf9 insect cells.
- Tags: N-terminal His and GST.
- Purity: >90.0% by reducing SDS-PAGE.
- Formulation: filtered solution in 50 mM Tris, 200 mM NaCl, 1 mM EDTA, 1 mM DTT, 10% glycerol, pH 7.4.
- Storage: store at -80 °C for long-term and avoid repeated freeze-thaw cycles.
- Intended use: for research use only.
Medchemexpress LLC L-Cysteine, L-γ-glutamyl-, 2,2,2-trifluoroacetate (1:1) | 283159-88-6 | 95.2% | 364.30 | 1 ML
Gamma-glutamylcysteine TFA (γ-Glutamylcysteine TFA) is an orally active, blood-brain barrier permeable dipeptide. It activates various signaling pathways like AMPK and Nrf2, while inhibiting others such as NF-κB and MAPKs. This compound regulates macrophage polarization, induces glutathione synthesis, improves metabolic dysfunction, and alleviates hepatic lipid droplet formation.
- Applicable to research related to inflammatory bowel disease.
- Applicable to research related to type 2 diabetes.
- Applicable to research related to cadmium-induced neurotoxicity.
- Applicable to research related to Alzheimer's disease.
- Applicable to research related to cerebral ischemia/reperfusion injury.
- Applicable to research related to neuropathy.
- Applicable to research related to alcoholic liver disease.
eMolecules 174180-53-1 | TERT-BUTYL 2-(HYDROXYMETHYL)-1H-INDOLE-1-CARBOXYLATE | AstaTech | MFCD09032312 | 247.294 | C14H17NO3 | 95.000 | CC(C)(C)OC(=O)n1c(CO)cc2ccccc12 | 0.25g | 261441238
TERT-BUTYL 2-(HYDROXYMETHYL)-1H-INDOLE-1-CARBOXYLATE | AstaTech | 174180-53-1 | MFCD09032312 | 247.294 | C14H17NO3 | 95.000 | CC(C)(C)OC(=O)n1c(CO)cc2ccccc12 | 0.25g | 261441238
Medchemexpress LLC AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) | ≥98.0% | 160 kDa | 10 UG
AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) | ≥98.0% | 160 kDa | 10 UG
![eMolecules 442877-23-8 | REL-(3AR,5S,6AS)-2-[(TERT-BUTOXY)CARBONYL]-OCTAHYDROCYCLOPENTA[C]PYRROLE-5-CARBOXYLIC ACID | AstaTech255.314 | C13H21NO4 | 95.000 | CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H](C[C@@H]2C1)C(O)=O | 0.25g | 388699851](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502172194.JPG-250.jpg)
eMolecules 442877-23-8 | REL-(3AR,5S,6AS)-2-[(TERT-BUTOXY)CARBONYL]-OCTAHYDROCYCLOPENTA[C]PYRROLE-5-CARBOXYLIC ACID | AstaTech255.314 | C13H21NO4 | 95.000 | CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H](C[C@@H]2C1)C(O)=O | 0.25g | 388699851
REL-(3AR,5S,6AS)-2-[(TERT-BUTOXY)CARBONYL]-OCTAHYDROCYCLOPENTA[C]PYRROLE-5-CARBOXYLIC ACID | AstaTech | 442877-23-8255.314 | C13H21NO4 | 95.000 | CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H](C[C@@H]2C1)C(O)=O | 0.25g | 388699851
